ADH1C (NM_000669) Human Untagged Clone

CAT#: SC119752

ADH1C (untagged)-Human alcohol dehydrogenase 1C (class I), gamma polypeptide (ADH1C)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADH1C
• Synonyms: ADH3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000669, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCACAGCAGGAAAAGTAATCAAATGCAAAGCAGCTGTGCTATGGGAGTTAAAGAAACCCTTTTCCA
  TTGAGGAGGTAGAGGTTGCACCTCCTAAGGCTCATGAAGTTCGCATTAAGATGGTGGCTGCAGGAATCTG
  TCGTTCAGATGAGCATGTGGTTAGTGGCAACCTGGTGACCCCCCTTCCTGTGATTTTAGGCCATGAGGCA
  GCCGGCATCGTGGAAAGTGTTGGAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCT
  TTACTCCTCAGTGTGGAAAATGCAGAATTTGTAAAAACCCAGAAAGCAACTACTGCTTGAAAAATGATCT
  AGGCAATCCTCGGGGGACCCTGCAGGATGGCACCAGGAGGTTCACCTGCAGCGGGAAGCCCATCCACCAC
  TTCGTCGGCGTCAGCACCTTCTCCCAGTACACAGTGGTGGATGAGAATGCAGTGGCCAAAATTGATGCAG
  CCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTTTCGACTGGTTATGGGTCTGCAGTCAAAGT
  TGCCAAGGTCACCCCAGGGTCTACCTGTGCTGTGTTTGGCCTGGGAGGGGTCGGCCTATCTGTTGTTATG
  GGCTGTAAAGCAGCTGGAGCAGCCAGAATCATTGCTGTGGACATCAACAAGGACAAATTTGCAAAGGCTA
  AAGAGTTGGGTGCCACTGAATGCATCAACCCTCAAGACTACAAGAAACCCATTCAGGAAGTGCTAAAGGA
  AATGACTGATGGAGGTGTGGATTTTTCGTTTGAAGTCATCGGTCGGCTTGACACCATGATGGCTTCCCTG
  TTATGTTGTCATGAGGCATGTGGCACAAGTGTCATTGTAGGGGTACCTCCTGATTCCCAGAACCTCTCAA
  TAAACCCTATGCTGCTACTGACTGGACGCACGTGGAAAGGAGCTATTTTTGGAGGCTTTAAGAGTAAAGA
  ATCTGTCCCCAAACTTGTGGCTGACTTTATGGCTAAGAAGTTTTCACTGGATGCATTAATAACAAATATT
  TTACCTTTTGAAAAAATAAATGAAGGATTTGACCTGCTTCGCTCTGGAAAGAGTATCCGTACCGTCCTGA
  CGTTTTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000669 unedited
  GGAATTTGTATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGCCCATTTCTTTATG
  ATTTGATAGTCTGAGAAGAAACGACGGGTGTGGCTTAAAAACCTAGATCACGTGTGTAGT
  TGGAATTGGGTGTTATATGAGCAAACAAAATAAATACCTGTGCAACATACCTGCTTTATG
  CACTCAAGCAGAGAAGAAATCCACAAGTACTCACCAGCCTCCTGGTCTGCAGAGAAGACA
  GAATCAATATGAGCACAGCAGGAAAAGTAATCAAATGCAAAGCAGCTGTGCTATGGGAGT
  TAAAGAAACCCTTTTCCATTGAGGAGGTAGAGGTTGCACCTCCTAAGGCTCATGAAGTTC
  GCATTAAGATGGTGGCTGCAGGAATCTGTCGTTCAGATGAGCATGTGGTTAGTGGCAACC
  TGGTGACCCCCCTTCCTGTGATTTTAGGCCATGAGGCAGCCGGCATCGTGGAAAGTGTTG
  GAGAAGGGGTGACTACAGTCAAACCAGGTGATAAAGTCATCCCGCTCTTTACTCCTCAGT
  GTGGAAAATGCAGAATTTGTAAAAACCCAGAAAGCAACTACTGCTTGAAAAATGATCTAG
  GCAATCCTCGGGGGACCCTGCAGGATGGCACCAGGAGGTTCACCTGCAGCGGGAAGCCCA
  TCCACCACTTCGTCGGCGTCAGCACCTTCTCCCATACACGGTGGTGGATGAGAATGCAGT
  GGCCAAAATTGATGCAGCCTCGCCCCTGGAGAAAGTCTGCCTCATTGGCTGTGGATTNTC
  GACTGGNTATGGGTCTGCAGTCAAAGTTGCCAAGGTCACCCCAGGNTCTACCTGTGCTGT
  NGTTGGCCCTGGAGGNNGTCGNCTATCTGNTGTTATGGGCTGTAAGCAGCTGNAGCANCA
  NAATCATGCTGTGGACTCACAAGGACAATTGCAANGCTAAGAGTGGNTGCACTGATGCTC
  ACCTNAGACTACAGAACATTCAGATGCTAAGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000669 unedited
  CTTACTTGNACCGCGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTTTTAATGGT
  TAAGAAGGAAGGTTTATTGGCTTCAATTCCCCAGTTGATGTTCAACACTTTATTTAGTTC
  TCATTTGGATTTTAAACATTTGCTTGACAAATAATTTCCCATCAATTTCCATTTCTTTGG
  AAAGCTCCCACGTGTAATTTATTTTTAACATCTCTGAAGAGCAGAATTAATGATATTTCC
  TAGCTGTTGCTCCAGATCATGTAGGGTAGAGGAGGCTGAAAACTGCTACAAGGGAAGGCA
  TCTGTATTGTTTCAAAACGTCAGGACGGTACGGATACTCTTTCCAGAGCGAAGCAGGTCA
  AATCCTTCATTTATTTTTTCAAAAGGTAAAATATTTGTTATTAATGCATCCAGTGAAAAC
  TTCTTAGCCATAAAGTCAGCCACAAGTTTGGGGACAGATTCTTTACTCTTAAAGCCTCCA
  AAAATAGCTCCTTTCCACGTGCGTCCAGTCAGTAGCAGCATAGGGTTTATTGAGAGGTTC
  TGGGAATCAGGAGGTACCCCTACAATGACACTTGTGCCACATGCCTCATGACAACATAAC
  AGGGAAGCCATCATGGTGTCAAGCCGACCGATGACTTCAAACGAAAAATCCACACCTCCA
  TCAGTCATTTCCTTTAGCACTTCCTGAATGGGTTTCTTGTAGTCTTGAGGGGTGATGCAT
  TCAGTGGCACCCAACTCTNTAGCCNNTTGCAATTTGTCCTTGNTGATGTCCACAGCAATG
  ATNCTGGCTGCTTCAGCTGCTTTACAGCCCCATACAACAGATAAGCCGACCCCTCCCAGC
  CAAACCAGNACAAGTAGACCCTGGGGTGACCTNGNCACTTNGACTGCNGACCCATACCCG
  TCGAAATCCCCAGCCCATGAGCAGACTTTCTCCAGGGGCGAGGCTGCATCATTTTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000669
• Insert Size: 1650 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000669.3, NP_000660.1
• RefSeq Size: 1497 bp
• RefSeq ORF: 1128 bp
• Locus ID: 126
• UniProt ID: P00326
• Cytogenetics: 4q23
• Domains: ADH_zinc_N
• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism
• Gene Summary: This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation to acetaldehyde, thus playing a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. An association between ADH1C polymorphism and alcohol dependence has not been established. [provided by RefSeq, Sep 2019]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.