Uridine Phosphorylase 1 (UPP1) (NM_003364) Human Untagged Clone

CAT#: SC118012

UPP1 (untagged)-Human uridine phosphorylase 1 (UPP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Uridine Phosphorylase 1
• Synonyms: UDRPASE; UP; UPASE; UPP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118012 sequence for NM_003364 edited (data generated by NextGen Sequencing)
  ATGGCGGCCACGGGAGCCAATGCAGAGAAAGCTGAAAGTCACAATGATTGCCCCGTCAGA
  CTTTTAAATCCAAACATAGCAAAAATGAAAGAAGATATTCTCTATCATTTCAATCTCACC
  ACTAGCAGACACAATTTCCCAGCCTTGTTTGGAGATGTGAAGTTTGTGTGTGTTGGTGGA
  AGCCCCTCCCGGATGAAAGCCTTCATCAGGTGCGTTGGTGCAGAGCTGGGCCTTGACTGC
  CCAGGTAGAGACTATCCCAACATCTGTGCGGGAACTGACCGCTATGCCATGTATAAAGTA
  GGACCGGTGCTGTCTGTCAGTCATGGTATGGGCATTCCTTCTATCTCAATCATGTTGCAT
  GAGCTCATAAAGCTGCTGTACTATGCCCGGTGCTCCAACGTCACTATCATCCGCATTGGC
  ACTTCTGGTGGGATAGGTCTGGAGCCCGGCACTGTGGTCATAACAGAGCAGGCAGTGGAT
  ACCTGCTTCAAGGCAGAGTTTGAGCAGATTGTCCTGGGGAAGCGGGTCATCCGGAAAACG
  GACCTTAACAAGAAGCTGGTGCAGGAGCTGTTGCTGTGTTCTGCAGAGCTGAGCGAGTTC
  ACCACAGTGGTGGGGAACACCATGTGCACCTTGGACTTCTATGAAGGGCAAGGCCGTCTG
  GATGGGGCTCTCTGCTCCTACACGGAGAAGGACAAGCAGGCGTATCTGGAGGCAGCCTAT
  GCAGCCGGCGTCCGCAATATCGAGATGGAGTCCTCGGTGTTTGCCGCCATGTGCAGCGCC
  TGCGGCCTCCAAGCGGCCGTGGTGTGTGTCACCCTCCTGAACCGCCTGGAAGGGGACCAG
  ATCAGCAGCCCTCGCAATGTGCTCAGCGAGTACCAGCAGAGGCCGCAGCGGCTGGTGAGC
  TACTTCATCAAGAAGAAACTGAGCAAGGCCTGA
  
  Clone variation with respect to NM_003364.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003364 unedited
  GGGGGCCCCCCANNNCCTTCCNCNCCCCCTGTTCAAATTTGTNATACGACTCACTATAGG
  CGGCCGCGAATTCGCACGAGGTTCCCTCATTCGAGTGCTCCGGCGCACAGACCCGCGCCC
  CGCCGTCCGCGAGCCTCCCGAGAGCCGTCCCTTCGTCCGGCCCTGGAGCATTGCGTTTGT
  CGCCGGTGTCGCAGTGCGAGGATGGCGCCGCGGGTGTAGCGGCTCTCTGCGCAGGCCGAG
  TGGGCCCAGAGAAGCGAGGAACTCCGCAGCTCGTCGACACGTCTCGTCTCCTGTCCCAAT
  TCAGGGCTTGGTGAGGTGACTCGCGGTCGCGGGTGACTCGCCGGCAGGACACTGCCTGGA
  ACGCCTGGAGCGCCTCCCACTGCAGACGTCTGTCCGCCTCCAGCCGCTCTCCTCTGACGG
  GTCCTGCCTCAGTTGGCGGAATGGCGGCCACGGGAGCCAATGCAGAGAAAGCTGAAAGTC
  ACAATGATTGCCCCGTCAGACTTTTAAATCCAAACATAGCAAAAATGAAAGAAGATATTC
  TCTATCATTTCAATCTCACCACTAGCAGACACAATTTCCCAGCCTTGTTTGGAGATGTGA
  AGTTTGTGTGTGTTGGTGGAAGCCCCTCCCGGATGAAAGCCTTCATCANGTGCGTTGGTG
  CAGAGCTGGGCCTTGACTGCCCAGNTAGAGACTATCCCAACATCTGTGCGGGAACTGACC
  GCTATGCCATGTANTAAGTANGACCCGGTGCTGTCTGTCAGTCATGGTATGGGCATTCCT
  TCTATCTCAATCATGGTGCATGAGCTCATAAAGCTGCTGTACTATGCCCNGGTGCTCCAC
  GTCACTATCATCCCGCATTGGCACTTCTGGTGGGATAAGGNCTGAAGCCCGGCACTGTGG
  TCATTACAGAGCAGGCAGTGGAATACCTGCTCAGGNCAAAGTTTGAGCANAATTGTCCTG
  GGNAAGCGGGTCATCCCGGAAAACGGACCTTACAAGAAGCTGGTGCAGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003364 unedited
  NGGGCCTTCTATGNACCGCGCCGCTTTCTAAGATCGATTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGACAAAGCTTTTAATGGGAAGTCA
  TCACAACAAGTCTGCGGAGGGGCAAGGGAACGCTCAAGCCCTGGTCAATTTTTTTTTGAA
  GAAATAACTCACCAACCCCTGGGGCCCCTGGTGGGACCCGCTGAACACATTGGGAGGGCT
  GGTGATTTGGTCCCCTTTCAAGCGGGTTAAGAGGGGGACACACACCCCCGCCCCTTGGAG
  GCCCCAAGCCCCTCACATGGGGGGAAAAACCCAGGACCCCCTCTTGATTTTGGGGACCCC
  CGCTGGATAAGCTGCCCCCAAAAACCCCCGGTTGTCCTTTTCCCGGTAGGAACAAAAAGC
  CCCATTCAAAAAGGCTTGGCCTTTATAAAAATCCAAAGGGCCCATGGGGGTCCCCACCCC
  TGGGGGGAAATCGCTCAACTTTGGAAAACAAAAAAACAACTTCTGGACCAACTTTTTGTT
  AAAGGCCCTTTTCCGGATGAACCCCTTTCCCAAGACAAACTGGTCAAACTCTGCCCTGAA
  ACAAGGATCCCCCGGCCGCTCTGGTATGAACACAATGGCCGGGTTCAGACCATCCCACCC
  AAAATGCCCATGCCGATTATAATGACCTTTGAACACCCGGCATTATACCACAACTTTTTG
  AACCCTGCCACATGGTTGGGAAAAAAAGAATGCCCCTTCCCTTGGTGGAAGAAAAAACCC
  GGGCCCATTTTTTACATGGGATAACGGGCAATTTCCCCACAGATGGTGGGGAAATCCCTA
  CCCGGGCAGATAAGGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003364
• Insert Size: 1250 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003364.2, NP_003355.1
• RefSeq Size: 1796 bp
• RefSeq ORF: 933 bp
• Locus ID: 7378
• UniProt ID: Q16831
• Cytogenetics: 7p12.3
• Domains: PNP_UDP_1
• Protein Pathways: Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism
• Gene Summary: This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides. [provided by RefSeq, Oct 2016]
  Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 8. Variants 1, 3 and 8 encode the same isoform (a).