DcR2 (TNFRSF10D) (NM_003840) Human Untagged Clone

CAT#: SC117708

TNFRSF10D (untagged)-Human tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain (TNFRSF10D)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DcR2
• Synonyms: CD264; DCR2; TRAIL-R4; TRAILR4; TRUNDD
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117708 sequence for NM_003840 edited (data generated by NextGen Sequencing)
  ATGGGACTTTGGGGACAAAGCGTCCCGACCGCCTCGAGCGCTCGAGCAGGGCGCTATCCA
  GGAGCCAGGACAGCGTCGGGAACCAGACCATGGCTCCTGGACTCCAAGATCCTTAAGTTC
  GTCGTCTTCATCGTCGCGGTTCTGCTGCCGGTCCGGGTTGACTCTGCCACCATCCCCCGG
  CAGGACGAAGTTCCCCAGCAGACAGTGGCCCCACAGCAACAGAGGCGCAGCCTCAAGGAG
  GAGGAGTGTCCAGCAGGATCTCATAGATCAGAATATACTGGAGCCTGTAACCCGTGCACA
  GAGGGTGTGGATTACACCATTGCTTCCAACAATTTGCCTTCTTGCCTGCTATGTACAGTT
  TGTAAATCAGGTCAAACAAATAAAAGTTCCTGTACCACGACCAGAGACACCGTGTGTCAG
  TGTGAAAAAGGAAGCTTCCAGGATAAAAACTCCCCTGAGATGTGCCGGACGTGTAGAACA
  GGGTGTCCCAGAGGGATGGTCAAGGTCAGTAATTGTACGCCCCGGAGTGACATCAAGTGC
  AAAAATGAATCAGCTGCCAGTTCCACTGGGAAAACCCCAGCAGCGGAGGAGACAGTGACC
  ACCATCCTGGGGATGCTTGCCTCTCCCTATCACTACCTTATCATCATAGTGGTTTTAGTC
  ATCATTTTAGCTGTGGTTGTGGTTGGCTTTTCATGTCGGAAGAAATTCATTTCTTACCTC
  AAAGGCATCTGCTCAGGTGGTGGAGGAGGTCCCGAACGTGTGCACAGAGTCCTTTTCCGG
  CGGCGTTCATGTCCTTCACGAGTTCCTGGGGCGGAGGACAATGCCCGCAACGAGACCCTG
  AGTAACAGATACTTGCAGCCCACCCAGGTCTCTGAGCAGGAAATCCAAGGTCAGGAGCTG
  GCAGAGCTAACAGGTGTGACTGTAGAGTCGCCAGAGGAGCCACAGCGTCTGCTGGAACAG
  GCAGAAGCTGAAGGGTGTCAGAGGAGGAGGCTGCTGGTTCCAGTGAATGACGCTGACTCC
  GCTGACATCAGCACCTTGCTGGATGCCTCGGCAACACTGGAAGAAGGACATGCAAAGGAA
  ACAATTCAGGACCAACTGGTGGGCTCCGAAAAGCTCTTTTATGAAGAAGATGAGGCAGGC
  TCTGCTACGTCCTGCCTGTGA
  
  Clone variation with respect to NM_003840.3
  103 c=>t;929 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003840 unedited
  TATACCCCGCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGC
  AGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCG
  AATTCGGCACGAGGGAGAACCTTTGCACGCGCACAAACTACGGGGACGATTTCTGATTGA
  TTTTTGGCGCTTTCGATCCACCCTCCTCCCTTCTCATGGGACTTTGGGGACAAAGCGTCC
  CGACCGCCTCGAGCGCTCGAGCAGGGCGCTATCCAGGAGCCAGGACAGCGTCGGGAACCA
  GACCATGGCTCCTGGACTCCAAGATCCTTAAGTTCGTCGTCTTCATCGTCGCGGTTCTGC
  TGCCGGTCCGGGTTGACTCTGCCACCATCCCCCGGCAGGACGAAGTTCCCCAGCAGACAG
  TGGCCCCACAGCAACAGAGGCGCAGCCTCAAGGAGGAGGAGTGTCCAGCAGGATCTCATA
  GATCAGAATATACTGGAGCCTGTAACCCGTGCACAGAGGGTGTGGATTACACCATTGCTT
  CCAACAATTTGCCTTCTTGCCTGCTATGTACAGTTTGTAAATCAGGTCAAACAAATAAAA
  GTTCCTGTACCACGACCAGAGACACCGTGTGTCAGTGTGAAAAAGGAAGCTTCCAGGATA
  AAAACTCCCCTGAGATGTGCCGGACGTGTAGAACAGGGTGTCCCANGAGGATGGTCAAGG
  TCAGTAATTGTACGCCCCGGAGTGACATCAAGTGCAAAAATGAATCAGCTGCCAGTTCCA
  CTGGGAAAACCCCAGCAGCGGGAGAGACAGTGACCACCATCCCTGGGGATGCTTTGCCTC
  TCCCTATCACTACCTTATCATCATAGTGGGTTTTAGTCATCATTTTAGCTGTGGNTGTGG
  GTGGCTTTTCATGTCGGNAAGAAATTCATTTCTTTACTCAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003840 unedited
  GGTATTACTATGTACGCGGCCGCTTTCTANATCGAGTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTAATATGAGGGTTCATATTTATTTTGGTCATAAACATATGAG
  TATTTCATATATAACCAGGTGTTATGTGCTATTTGGCCCGGGTATAAAGCAAAACCTAAA
  CAAATCAACCAACGCCAAAAAACCCCAACAATTTCATTTTTTTTGGAAGCTTATGTTAAA
  GGAATAAGCTTAAACACTGATAAGGCTGGTAGTCTAAATGCATCTTCAAGGAAGGCCTCT
  GAGGAAGGGACAAAGGAGCTGGGACCGGACTGGCTCTTTCCGAGCTTTGAAACCAAGTCT
  CCTGCACAGAAGGCCCAGCAAAGGCAAAGACTAGGAGGCAGCAGCCCCCTGTGTCATCCA
  AAAGTGCAGGGGACAAGGTGTGGGACCCCAAATGGAAATGGGAAAAGATGGAAATGCGAA
  AACCCGAAAGGCCATCCCCTCCTAAAACTCCCTGGGCACAACAATTTGAATGTGCGAACT
  TCAGGCAGTTTTTACTTTGGCCCAACCAAACCAGTCCCGGAACAAAACACACCATGCCTT
  GAGATGGAAAAAAATGAAACCCCTAAGAGGACTATTTCCCGCAATTTATCCTACCACCAA
  TGGGGTACTTGGGGGAAAAAATTTTGTGGGAAAAAAACTAAACCATTACTGGAGGTTTTT
  AAATAAAAAAAAGGGAACGTGGCCCAAGGCTCAAATGGGTACGCCCTTTTTAAAACCCCT
  TGGCCCAGGGGTTAAAAAATTAATTTTTTTTAGAAAAAGCAAAAACCTTTCCCAAGGGGG
  CCAGGTTCTCCAAAAAGGGGATATTTGCCCTTAAAAAACACTCCAGGAATTCTTTGCCTC
  AAAAGGAATCCCAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003840
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003840.3, NP_003831.2
• RefSeq Size: 3561 bp
• RefSeq ORF: 1161 bp
• Locus ID: 8793
• UniProt ID: Q9UBN6
• Cytogenetics: 8p21.3
• Domains: TNFR
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity
• Gene Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]