beta 2 Adrenergic Receptor(ADRB2) (NM_000024) Human Untagged Clone

CAT#: SC116997

ADRB2 (untagged)-Human adrenergic, beta-2-, receptor, surface (ADRB2)

USD 196.00


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Size
    • 10 ug

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Specifications

Product Data
Product Name beta 2 Adrenergic Receptor(ADRB2) (NM_000024) Human Untagged Clone
Symbol ADRB2
Synonyms ADRB2R; ADRBR; B2AR; BAR; BETA2AR
Vector pCMV6-XL5
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_000024 edited
GAATTCGGCACGAGGCAGGCACCGCGAGCCCCTAGCACCCGACAAGCTGAGTGTGCAGGA
CGAGTCCCCACCACACCCACACCACAGCCGCTGAATGAGGCTTCCAGGCGTCCGCTCGCG
GCCCGCAGAGCCCCGCCGTGGGTCCGCCTGCTGAGGCGCCCCCAGCCAGTGCGCTTACCT
GCCAGACTGCGCGCCATGGGGCAACCCGGGAACGGCAGCGCCTTCTTGCTGGCACCCAAT
GGAAGCCATGCGCCGGACCACGACGTCACGCAGCAAAGGGACGAGGTGTGGGTGGTGGGC
ATGGGCATCGTCATGTCTCTCATCGTCCTGGCCATCGTGTTTGGCAATGTGCTGGTCATC
ACAGCCATTGCCAAGTTCGAGCGTCTGCAGACGGTCACCAACTACTTCATCACTTCACTG
GCCTGTGCTGATCTGGTCATGGGCCTAGCAGTGGTGCCCTTTGGGGCCGCCCATATTCTT
ATGAAAATGTGGACTTTTGGCAACTTCTGGTGCGAGTTTTGGACTTCCATTGATGTGCTG
TGCGTCACGGCCAGCATTGAGACCCTGTGCGTGATCGCAGTGGATCGCTACTTTGCCATT
ACTTCACCTTTCAAGTACCAGAGCCTGCTGACCAAGAATAAGGCCCGGGTGATCATTCTG
ATGGTGTGGATTGTGTCAGGCCTTACCTCCTTCTTGCCCATTCAGATGCACTGGTACAGG
GCCACCCACCAGGAAGCCATCAACTGCTATGCCAATGAGACCTGCTGTGACTTCTTCACG
AACCAAGCCTATGCCATTGCCTCTTCCATCGTGTCCTTCTACGTTCCCCTGGTGATCATG
GTCTTCGTCTACTCCAGGGTCTTTCAGGAGGCCAAAAGGCAGCTCCAGAAGATTGACAAA
TCTGAGGGCCGCTTCCATGTCCAGAACCTTAGCCAGGTGGAGCAGGATGGGCGGACGGGG
CATGGACTCCGCAGATCTTCCAAGTTCTGCTTGAAGGAGCACAAAGCCCTCAAGACGTTA
GGCATCATCATGGGCACTTTCACCCTCTGCTGGCTGCCCTTCTTCATCGTTAACATTGTG
CATGTGATCCAGGATAACCTCATCCGTAAGGAAGTTTACATCCTCCTAAATTGGATAGGC
TATGTCAATTCTGGTTTCAATCCCCTTATCTACTGCCGGAGCCCAGATTTCAGGATTGCC
TTCCAGGAGCTTCTGTGCCTGCGCAGGTCTTCTTTGAAGGCCTATGGCAATGGCTACTCC
AGCAACGGCAACACAGGGGAGCAGAGTGGATATCACGTGGAACAGGAGAAAGAAAATAAA
CTGCTGTGTGAAGACCTCCCAGGCACGGAAGACTTTGTGGGCCATCAAGGTACTGTGCCT
AGCGATAACATTGATTCACAAGGGAGGAATTGTAGTACAAATGACTCACTGCTATAAAGC
AGTTTTTCTACTTTTAAAGACCCCCCCCCGCCCAACAGAACACTAAACAGACTATTTAAC
TTGAGGGTAATAAACTTAGAATAAAATTGTAAAATTGTATAGAGATATGCAGAAGGAAGG
GCATCCTTCTGCCTTTTTTATTTTTTTAAGCTGTAAAAAGAGAGAAAACTTATTTGAGTG
ATTATTTGTTATTTGTACAGTTCAGTTCCTCTTTGCATGGAATTTGTAAGTTTATGTCTA
AAGAGCTTTAGTCCTAGAGGACCTGAGTCTGCTATATTTTCATGACTTTTCCATGTATCT
ACCTCACTATTCAAGTATTAGGGGTAATATATTGCTGCTGGTAATTTGTATCTGAAGGAG
ATTTTCCTTCCTACACCCTTGGACTTGAGGATTTTGAGTATCTCGGACCTTTCAGCTGTG
AACATGGACTCTTCCCCCACTCCTCTTATTTGCTCACACGGGGTATTTTAGGCAGGGATT
TGAGGAGCAGCTTCAGTTGTTTTCCCGAGCAAAGTXXXXXXXXXXXXXXXAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAACTCGAC
5' Read Nucleotide Sequence
>OriGene 5' read for NM_000024 unedited
GCGGTCGAGATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCAGGCAC
CGCGAGCCCCTAGCACCCGACAAGCTGAGTGTGCAGGACGAGTCCCCACCACACCCACAC
CACAGCCGCTGAATGAGGCTTCCAGGCGTCCGCTCGCGGCCCGCAGAGCCCCGCCGTGGG
TCCGCCTGCTGAGGCGCCCCCAGCCAGTGCGCTTACCTGCCAGACTGCGCGCCATGGGGC
AACCCGGGAACGGCAGCGCCTTCTTGCTGGCACCCAATGGAAGCCATGCGCCGGACCACG
ACGTCACGCAGCAAAGGGACGAGGTGTGGGTGGTGGGCATGGGCATCGTCATGTCTCTCA
TCGTCCTGGCCATCGTGTTTGGCAATGTGCTGGTCATCACAGCCATTGCCAAGTTCGAGC
GTCTGCAGACGGTCACCAACTACTTCATCACTTCACTGGCCTGTGCTGATCTGGTCATGG
GCCTAGCAGTGGTGCCCTTTGGGGCCGCCCATATTCTTATGAAAATGTGGACTTTTGGCA
ACTTCTGGTGCGAGTTTTGGACTTCCATTGATGTGCTGTGCGTCACGGCCAGCATTGAGA
CCCTGTGCGTGATCGCAGTGGATCGCTACTTTGCCATTACTTCACCTTTCAAGTACCAGA
GCCTGCTGACCAAGAATAAGGCCCGGGTGATCATTCTGATGGTGTGGATTGTGTCAGGCC
TTACCTCCTTCTTGCCCATTCAGATGCACTGGTACAGGGCCACCCACCAGGAAGCCATCA
ACTGCTATGCCAATGAGACCTGCTGTGACTTCTTCACGAACCAAGCCTATGCCATTGCCT
CTTCCATCGTGTCCTTCTACGTTCCCCCTGGTGATCATGGTNCTTCGTCTACTCCAGGGT
C
3' Read Nucleotide Sequence
>OriGene 3' read for NM_000024 unedited
ACCTTCAGACATCTTATTACTGTAAACTTTATACTTTGCTCGGGAAACAACTGAAGCTGC
TCCTCAAATCCCTGCCTAAAATACCCCGTGTGAGCAAATAAGAGGAGTGGGGGAAGAGTC
CATGTTCACAGCTGAAAGGTCCGAGATACTCAAAATCCTCAAGTCCAAGGGTGTAGGAAG
GAAAATCTCCTTCAGATACAAATTACCAGCAGCAATATATTACCCCTAATACTTGAATAG
TGAGGTAGATACATGGAAAAGTCATGAAAATATAGCAGACTCAGGTCCTCTAGGACTAAA
GCTCTTTAGACATAAACTTACAAATTCCATGCAAAGAGGAACTGAACTGTACAAATAACA
AATAATCACTCAAATAAGTTTTCTCTCTTTTTACAGCTTAAAAAAATAAAAAAGGCAGAA
GGATGCCCTTCCTTCTGCATATCTCTATACAATTTTACAATTTTATTCTAAGTTTATTAC
CCTCAAGTTAAATAGTCTGTTTAGTGTTCTGTTGGGCGGGGGGGGGTCTTTAAAAGTAGA
AAAACTGCTTTATAGCAGTGAGTCATTTGTACTACAATTCCTCCCTTGTGAATCAATGTT
ATCGCTAGGCACAGTACCTTGATGGCCCACAAAGTCTTCCGTGCCTGGGAAGTCTTCACA
CAGCAGTTTATTTTCTTTCTCCTGTTCCACGTGATATCCACTCTGCTCCCCTGTGTTGCC
GTTGCTGGAGTAGCCATTGCCATANGCCTTCAAAGAGACCTGCGCAGCACAGAAGCTCCT
GGAAGGCATCCTNGAATCTGGGCTCCNGCAGTAGATAAGGGGATTGAAACCAGAATTGAC
ATAGCCTATCCAATTGAGAAGATGTAAACTTCCNTACGATGANGTATCCTGGATCAATGC
ACATGTAACGATGAAGAAGGCAA
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN NM_000024
ORF Size 1242 bp
Insert Size 2050
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_000024.3, NP_000015
RefSeq Size 2015
Locus ID 154
Cytogenetics 5q32
Domains 7tm_1
Protein Families GPCR, Transmembrane, Druggable Genome
Protein Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction, Endocytosis
Gene Summary This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations