USPL1 (NM_005800) Human Untagged Clone

CAT#: SC116537

USPL1 (untagged)-Human ubiquitin specific peptidase like 1 (USPL1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: USPL1
• Synonyms: bA121O19.1; C13orf22; D13S106E
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116537 sequence for NM_005800 edited (data generated by NextGen Sequencing)
  ATGATGGATTCTCCGAAGATTGGAAATGGTTTGCCAGTGATTGGACCAGGGACTGATATA
  GGGATATCTTCACTCCACATGGTGGGGTATTTGGGAAAAAATTTTGATTCAGCTAAAGTT
  CCATCAGATGAGTATTGCCCTGCTTGTAGAGAGAAGGGAAAGTTAAAAGCCTTAAAGACT
  TACCGAATTAGTTTTCAAGAATCTATCTTTTTGTGTGAGGATCTGCAGTGCATCTATCCT
  TTGGGCTCTAAATCACTTAATAACCTAATTTCTCCTGATTTGGAAGAATGTCACACTCCA
  CATAAGCCTCAGAAAAGGAAGAGCTTAGAAAGCAGCTATAAGGATTCACTTCTTTTAGCA
  AATTCCAAAAAGACTAGAAATTATATTGCTATTGACGGTGGAAAAGTTTTGAACAGCAAA
  CATAATGGAGAAGTATATGACGAAACCTCGTCAAACTTACCTGATAGTAGTGGTCAACAG
  AATCCAATTAGGACAGCTGATTCCTTGGAGCGGAATGAGATTTTGGAAGCTGATACTGTT
  GACATGGCTACTACAAAAGATCCTGCTACAGTTGATGTCTCTGGAACTGGCAGACCTTCC
  CCTCAAAATGAAGGATGTACATCTAAACTGGAAATGCCACTGGAGAGCAAATGTACATCA
  TTTCCCCAGGCTTTATGTGTCCAGTGGAAAAATGCTTATGCTCTCTGTTGGTTAGACTGT
  ATCCTGTCAGCTTTGGTGCACTCGGAAGAGTTAAAGAACACCGTGACTGGACTGTGCTCG
  AAGGAGGAATCTATATTCTGGCGGTTGCTTACAAAATATAATCAAGCAAATACACTTCTA
  TATACCAGTCAATTGAGTGGTGTTAAAGATGGAGATTGTAAAAAACTTACCTCAGAAATA
  TTTGCAGAGATAGAGACCTGTCTGAATGAAGTTAGAGATGAAATTTTTATTAGCCTTCAG
  CCCCAGCTTAGATGCACATTAGGTGATATGGAAAGCCCTGTGTTTGCATTTCCCCTGCTC
  TTAAAACTAGAAACCCACATTGAAAAGCTCTTCCTATATTCTTTTTCTTGGGACTTTGAA
  TGTTCGCAGTGTGGACACCAATATCAAAACAGGCATATGAAGAGTCTGGTCACCTTTACA
  AATGTCATCCCTGAGTGGCACCCACTTAATGCTGCCCATTTTGGTCCATGTAACAATTGC
  AACAGTAAATCACAAATAAGAAAAATGGTATTAGAAAAAGTATCTCCCATATTCATGTTG
  CACTTTGTAGAAGGCTTACCACAGAATGACTTGCAGCACTATGCATTTCATTTTGAAGGC
  TGTCTTTATCAGATAACTTCTGTAATTCAGTATCGAGCAAATAATCATTTTATAACATGG
  ATTTTAGATGCTGATGGAAGTTGGCTGGAATGTGATGACTTAAAAGGCCCATGTTCTGAA
  AGGCACAAGAAATTTGAAGTTCCTGCTTCAGAGATACATATTGTTATTTGGGAAAGAAAA
  ATATCCCAAGTGACAGATAAAGAAGCTGCCTGCCTTCCACTTAAAAAGACTAATGACCAA
  CACGCTCTCAGTAATGAGAAACCAGTATCTTCAACATCGTGTTCTGTGGGTGATGCTGCC
  TCAGCTGAAACAGCCTCAGTAACTCACCCTAAAGATATATCAGTTGCCCCTCGTACTCTT
  TCACAGGACACAGCTGTAACTCATGGAGATCATTTACTTTCAGGTCCAAAAGGTTTGGTT
  GACAATATTTTACCTCTGACACTTGAAGAAACTATCCAGAAAACAGCCTCAGTTTCACAG
  TTAAATTCTGAAGCTTTCCTGTTAGAAAATAAACCTGTAGCAGAAAATACAGGAATTCTC
  AAAACCAATACTTTGCTATCACAAGAATCACTAATGGCTTCTTCAGTATCAGCTCCATGT
  AATGAAAAGCTTATTCAAGACCAATTTGTGGACATAAGTTTTCCATCCCAAGTTGTAAAT
  ACAAACATGCAGTCAGTACAGCTGAATACAGAAGATACTGTAAATACTAAATCTGTGAAT
  AATACTGATGCTACTGGTCTTATACAGGGAGTGAAGTCAGTAGAAATTGAGAAGGACGCT
  CAGTTAAAACAATTCCTTACACCAAAAACTGAACAATTAAAACCAGAACGTGTCACATCT
  CAGGTATCTAATTTGAAGAAAAAAGAAACTACAGCAGATTCTCAAACCACAACATCTAAG
  TCATTACAGAATCAGTCTCTGAAAGAAAATCAGAAGAAGCCATTTGTGGGAAGTTGGGTT
  AAAGGCTTAATAAGCAGGGGTGCTTCTTTTATGCCACTCTGTGTTTCAGCTCATAATAGA
  AACACTATAACTGATTTACAACCTTCAGTTAAAGGGGTAAATAATTTTGGTGGCTTTAAA
  ACTAAAGGTATAAACCAGAAGGCCAGCCACGTATCCAAGAAAGCTCGTAAGAGTGCAAGT
  AAGCCTCCTCCCATCAGTAAGCCACCAGCAGGCCCTCCATCGTCTAATGGCACAGCTGCC
  CACCCACATGCTCATGCTGCTTCAGAAGTTTTGGAAAAGTCTGGAAGCACCTCATGTGGA
  GCTCAACTCAACCACAGTTCTTATGGGAATGGTATTTCTTCAGCAAACCATGAAGACTTG
  GTGGAAGGTCAGATTCATAAACTTCGTCTAAAACTTCGTAAAAAGCTAAAGGCAGAAAAG
  AAGAAATTAGCTGCTCTTATGTCTTCCCCGCAAAGCAGAACAGTTCGAAGTGAAAATCTA
  GAACAGGTGCCCCAGGATGGGTCTCCAAATGATTGTGAATCAATAGAGGACTTGTTAAAT
  GAGCTACCATATCCAATTGATATTGCCAATGAGTCTGCATGCACCACTGTTCCTGGTGTT
  TCCCTGTACAGTAGTCAAACTCATGAAGAAATTTTAGCGGAATTATTGTCTCCTACACCT
  GTTTCAACAGAGCTGTCAGAAAATGGGGAAGGTGACTTTAGGTATTTGGGAATGGGAGAT
  AGTCATATCCCACCACCAGTACCAAGTGAATTCAATGATGTTTCCCAGAACACACATCTG
  AGACAGGACCATAATTATTGTAGCCCCACCAAGAAAAATCCATGTGAAGTTCAGCCAGAC
  TCTCTGACAAATAATGCCTGCGTTAGAACATTAAACTTGGAGAGTCCGATGAAGACTGAT
  ATTTTCGATGAGTTTTTTTCCTCCTCAGCATTAAATGCTTTAGCAAATGACACATTAGAC
  CTACCTCATTTCGATGAATATCTGTTTGAGAATTATTGA
  
  Clone variation with respect to NM_005800.4
  1592 t=>c;2849 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005800 unedited
  TAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGTGGAGACGCGAGTGGGGG
  AGGAGCAGTCCGAGGGGAACGTGGGTTGAACGTTGCAACTAGGGTGGAGATCAAGCTGGA
  ACAGGAGTTCCGATCGACCCGGTACCAAGAAGGGGAGTGCCCGCGGCAGGGTTCATTGAA
  AAAATCCTTAGTGATATTGACATGTCTCAAGTGACATAAATTAGCCAATGACTCGGAATG
  ATGGATTCTCCGAAGATTGGAAATGGTTTGCCAGTGATTGGACCAGGGACTGATATAGGG
  ATATCTTCACTCCACATGGTGGGGTATTTGGGAAAAAATTTTGATTCAGCTAAAGTTCCA
  TCAGATGAGTATTGCCCTGCTTGTAGAGAGAAGGGAAAGTTAAAAGCCTTAAAGACTTAC
  CGAATTAGTTTTCAAGAATCTATCTTTTTGTGTGAGGATCTGCAGTGCATCTATCCTTTG
  GGCTCTAAATCACTTAATAACCTAATTTCTCCTGATTTGGAAGAATGTCACACTCCACAT
  AAGCCTCAGAAAAGGAAGAGCTTAGAAAGCAGCTATAAGGATTCACTTCTTTTAGCAAAT
  TCCAAAAAGACTAGAAATTATATTGCTATTGACGGTGGAAAAGTTTTGAACAGCAAACAT
  AATGGAGAAGTATATGACGANACCTCGTCAAACTTACCTGATAGTAGTGGTCAACAGAAT
  CCAATTAGGACAGCTGATTCCTTGGAGCGGAATGAGATTTGGAAGCTGATACTGGTGACA
  TGGCTACTACAAAAGACCTGCTAACTTGATGTCTCTGGACCTGCACACCTTCCCTCAAAT
  GAAGGATGTCCATCTAACTGGGAAAGGCACTGGAAAGCAAATGACATCATTTTCCCAGCC
  TTATGTGTCCAGGGGAAAATGCTTATGCTCTCTGTTGGTAGAACG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005800 unedited
  TATGAACCGCGNGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTAACACATTCAGGGATTTTAATGGGTAAAAAAAAA
  ACTTGCTTTTTGGGCAAAACCAAAGGTTAAACCTTGCTTTTTGTTCATGGTTTTTACCCA
  AGTAATTCCCCAAGTCCAGGGTTTAAACCCTACCTGAACACATTGGAAGTTTTTTTAATA
  ATAATAAATTTTTTTTGAAAAAAGTTAACAACCTTTATTTCAATATTTTTCAAACAAATT
  TTCATCAAAATGAGGGAGGTCTAAGGGGTCATTTGCTAAAGCATTTAATGCTGGGGAGGA
  AAAAAACTCTTCGAAAATTTCAGTTTTTATCGGACTTTCCAAGTTTAATGTTTTAACCCA
  GGCTTTTTTTGTCAAAAAGTCTGGCTGAACTTCACATGGATTTTTTTTGGGGGGGCTACA
  ATAATTATGGCCCTGTCTCAAATGGGGGTTCTGGGAAACATCATTGAATTCACTTGGGAC
  TGGGGGGGGGATATAACTATTTCCCATTCCCAAATACCTAAAGGCCCCTTCCCCATTTTT
  TGACAGCTTTGTTAAAACAGGGGTAGGAAACAATAATTCCGCTAAAATTTCTTCATGAGT
  TTGACTACTGGCCAGGGAAACCCCAGGAACAGGGGGGCCTGCAAACTCATTGGCAATATC
  AATTGGATATGGGAGCTCATTTAACAAGTTCTCTATTGATTCACAATCATTTGGAAACCC
  ATCCTGGGGCCACGTGTTCTAAATTTCACTTCCAACTGTTTTGCTTTGCGGGGAACACTA
  AANAGCACTAATTTCTTCTTTCCTGCTTTACCTTTTTACAGNTTTAAACAAATTAAGAAT
  CTGACCTCCACCAATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005800
• Insert Size: 3670 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005800.3, NP_005791.2
• RefSeq Size: 3829 bp
• RefSeq ORF: 3279 bp
• Locus ID: 10208
• UniProt ID: Q5W0Q7
• Cytogenetics: 13q12.3
• Gene Summary: SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for SUMO2 and SUMO3 which it cleaves more efficiently. Also able to process full-length SUMO proteins to their mature forms (PubMed:22878415). Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (PubMed:24413172). Is a component of complexes that can bind to U snRNA genes (PubMed:24413172).[UniProtKB/Swiss-Prot Function]