VPS26C (NM_006052) Human Untagged Clone

CAT#: SC116380

DSCR3 (untagged)-Human Down syndrome critical region gene 3 (DSCR3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VPS26C
• Synonyms: DCRA; DSCR3; DSCRA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006052, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGACCGCCCTGGACATCAAGATTAAAAGAGCGAATAAAGTTTATCACGCCGGGGAAGTGCTCTCTG
  GCGTGGTGGTCATATCGAGTAAGGATTCAGTCCAACACCAGGGAGTGTCTTTGACCATGGAAGGAACTGT
  AAACCTCCAGCTCAGTGCCAAAAGTGTGGGTGTGTTTGAAGCTTTTTATAATTCTGTTAAGCCTATCCAG
  ATTATCAACAGCACCATAGAAATGGTGAAGCCGGGGAAATTTCCCAGCGGCAAAACAGAAATCCCTTTTG
  AATTTCCTCTGCACTTGAAGGGTAACAAAGTTCTGTATGAGACGTATCATGGCGTGTTTGTCAACATTCA
  GTATACACTGCGCTGTGACATGAAGCGGTCTCTGTTGGCCAAGGACTTGACAAAGACCTGTGAATTTATC
  GTTCACTCCGCTCCTCAGAAGGGGAAGTTTACTCCCAGTCCCGTGGACTTCACGATTACACCTGAAACCT
  TACAGAACGTCAAAGAGAGAGCTTTGCTTCCCAAATTTCTCCTTCGAGGACATCTCAACTCAACAAACTG
  TGTCATCACGCAGCCACTAACGGGAGAGCTGGTGGTGGAGAGCTCGGAAGCCGCCATCAGAAGCGTGGAG
  CTGCAGCTGGTGCGCGTGGAGACGTGCGGGTGTGCAGAAGGCTATGCCCGCGACGCCACGGAGATTCAGA
  ACATTCAGATCGCCGACGGGGATGTGTGCAGGGGCCTCTCTGTCCCCATCTACATGGTCTTCCCTAGGCT
  GTTCACCTGCCCTACACTGGAGACCACCAACTTCAAAGTGGAATTTGAGGTTAACATCGTGGTGCTGCTT
  CACCCTGACCACCTCATCACGGAGAACTTCCCGCTGAAGCTCTGCAGGATATAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006052 unedited
  AGAGTCATATTTGTATACACTCACTATAGGCGGCCGCGAATTCGCACCGGGTGAACCGTG
  ACAGCGCTTCGGCCCGCACTAAGGCCGGCTCTTGTGCCGGAAGGAGGAAGGCGTGGGGCA
  TTCGCCCCTCGGAGCTAGGGAGTGTGTGCGACGCCGCTGCGAGGTCACGTGAGCCACTGC
  CGGCAGAGAGGGAAAGGGGCGGGGCCCAGAACGAAGCGGGGAGGCGCCCCTTGTTTCCCT
  GGGGTCACGCGCAGCCGGAAGTGGCGGCTGCTGCGGAGAATTGGAGATGGGGACCGCCCT
  GGACATCAAGATTAAAAGAGCGAATAAAGTTTATCACGCCGGGGAAGTGCTCTCTGGCGT
  GGTGGTCATATCGAGTAAGGATTCAGTCCAACACCAGGGAGTGTCTTTGACCATGGAAGG
  AACTGTAAACCTCCAGCTCAGTGCCAAAAGTGTGGGTGTGTTTGAAGCTTTTTATAATTC
  TGTTAAGCCTATCCAGATTATCAACAGCACCATAGAAATGGTGAAGCCGGGGAAATTTCC
  CAGCGGCAAAACAGAAATCCCTTTTGAATTTCCTCTGCACTTGAAGGGTAACAAAGTTCT
  GTATGAGACGTATCATGGCGTGTTTGTCAACATTCAGTATACACTGCGCTGTGACATGAA
  GCGGTCTCTGTTGGCCAAGACTTGACAAAGACCTGTGAAATTTATCGTCACTCCCGCTCT
  CAGAGGGGGAAGTTACTCCCAGTCCCGTGGACTTCACGATTACACCCTGANACCTTACAG
  AACGTCAAAGAGAGAGCTTTTGCTTCCAAATTTCTCCTTCNAGGACATCTCAACTCAACA
  AACTGTGTCATCACGCAGCCCCTAACGGNAAAGCTTGTGGTGGAGAGCTCGNAAGGCGCC
  CTCAGGAGCCTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006052 unedited
  AAATCATTTATTAAATTACATAGCAATATACATNNCCCAAACCTTTTCTCAAAATTGTCA
  TTAGCTTTTTAAATTCGTTAAATTTTTCATCTCATTAAAAATGGTTTCTTCCTTTAAAAT
  TTCCCAGAAAGTGTGGCCTCTGTTTTCTGCTACTCAGTTTAAACACATCATCAAGGATAG
  ATAATTAATGTCAGGTGAGCATAAAAGGAGATTATAAACCAGAAATGTGTTTTCTGGGAA
  CCAAGTTTCAAGTGACTCAGATAAGTTTTATTAATTTCATGGGTGAAGCCCCTGGATAAA
  GCAGTGCCTAAATCAGGCTTGTTTACCCTTGGCATTATGTCACCAAACACTGTTTCAGGA
  TACTGGAAGTACATACAGCTTGGGAGGTCTTTGGCCTGAGCCTGTTTTGGCCAAGCCCAT
  CCAGAATGAAAAGTACAAAAGAAGGCTAGTGTGTGTGCAAAGCAGCATGGCTTATTTTGA
  GGTCCTATTAGTTGTGGGCCAACAAAACAGTGGCAGGATTTGAAGGAAGAAATGTATTGC
  AATAGTCCATATCCTTCGAACCACAAAGGGAGACTGANGAAATGCTGGCTNTANGCCAAA
  AAACCCTGGCTCAAACAGCTTCCTNCAGTGGCTCAGAGGCAGACCAAATTCATCAAGTCA
  AGGACCTTTTCCTGCTACCACCTTGCCGNAGAGGGGCCTTCACCANGCCCACCCTGCACA
  TGGGTTTTCTGCTGNTCAAAACCTACCCAGTTACAACGGGAGCAAACATACATGGTTTTC
  CCCTCATGTACTTTGCATTTAAATTATTCTTGGGAAACTGCTGGCGCCCAGTGGCTCCAA
  CCTGGAATTCTCACCCCTTTGGGAGGGCCAAAAACGGAGGATCACTTTGAGTTTAGAATT
  CAAAACAACCTGGGCACAATAGGAAACCCTTGCCCACAAAATTAAAATAACTCGGTGGGG
  GGCGCTCCCTGGNTCCACTCTTCGAGGCTTGAGGGGGGATCCTTTCCCAGAGGTTAGCTT
  CA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006052
• Insert Size: 3410 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006052.1, NP_006043.1
• RefSeq Size: 3252 bp
• RefSeq ORF: 894 bp
• Locus ID: 10311
• UniProt ID: O14972
• Cytogenetics: 21q22.13
• Domains: Vps26
• Gene Summary: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and cognitive disability. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]