MC3R (NM_019888) Human Untagged Clone

CAT#: SC113222

MC3R (untagged)-Human melanocortin 3 receptor (MC3R)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MC3R
• Synonyms: BMIQ9; MC3; MC3-R; OB20; OQTL
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_019888, RT-PCR generated
  ATGAGCATCCAAAAGAAGTATCTGGAGGGAGATTTTGTCTTTCCTGTGAGCAGCAGCAGC
  TTCCTACGGACCCTGCTGGAGCCCCAGCTCGGATCAGCCCTTCTGACAGCAATGAATGCT
  TCGTGCTGCCTGCCCTCTGTTCAGCCAACACTGCCTAATGGCTCGGAGCACCTCCAAGCC
  CCTTTCTTCAGCAACCAGAGCAGCAGCGCCTTCTGTGAGCAGGTCTTCATCAAGCCCGAG
  GTTTTCCTGTCTCTGGGCATCGTCAGTCTGCTGGAAAACATCCTGGTTATCCTGGCCGTG
  GTCAGGAACGGCAACCTGCACTCCCCGATGTACTTCTTTCTCTGCAGCCTGGCGGTGGCC
  GACATGCTGGTAAGTGTGTCCAATGCCCTGGAGACCATCATGATCGCCATCGTCCACAGC
  GACTACCTGACCTTCGAGGACCAGTTTATCCAGCACATGGACAACATCTTCGACTCCATG
  ATCTGCATCTCCCTGGTGGCCTCCATCTGCAACCTCCTGGCCATCGCCGTCGACAGGTAC
  GTCACCATCTTTTACGCGCTCCGCTACCACAGCATCATGACCGTGAGGAAGGCCCTCACC
  TTGATCGTGGCCATCTGGGTCTGCTGCGGCGTCTGTGGCGTGGTGTTCATCGTCTACTCG
  GAGAGCAAAATGGTCATTGTGTGCCTCATCACCATGTTCTTCGCCATGATGCTCCTCATG
  GGCACCCTCTACGTGCACATGTTCCTCTTTGCGCGGCTGCACGTCAAGCGCATAGCAGCA
  CTGCCACCTGCCGACGGGGTGGCCCCACAGCAACACTCATGCATGAAGGGGGCAGTCACC
  ATCACCATTCTCCTGGGCGTGTTCATCTTCTGCTGGGCCCCCTTCTTCCTCCACCTGGTC
  CTCATCATCACCTGCCCCACCAACCCCTACTGCATCTGCTACACTGCCCACTTCAACACC
  TACCTGGTCCTCATCATGTGCAACTCCGTCATCGACCCACTCATCTACGCTTTCCGGAGC
  CTGGAATTGCGCAACACCTTTAGGGAGATTCTCTGTGGCTGCAACGGCATGAACTTGGGA
  TAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_019888 unedited
  TTTGGGGATTTTTGGATTTGTNAAACGACTTCACTATAGGCGGCCGCCAGTCGTGAGGAT
  ATCTGCAGAATTCGGCTTATGAGCATCCAAAAGAATATCTGGAGGGAGATTTTGTCTTTC
  CTGTGAGCAGCAGCAGCTTCCTACGGACCCTGCTGGAGCCCCAGCTCGGATCAGCCCTTC
  TGACAGCAATGAATGCTTCGTGCTGCCTGCCCTCTGTTCAGCCAACACTGCCTAATGGCT
  CGGAGCACCTCCAAGCCCCTTTCTTCAGCAACCAGAGCAGCAGCGCCTTCTGTGAGCAGG
  TCTTCATCAAGCCCGAGGTTTTCCTGTCTCTGGGCATCGTCAGTCTGCTGGAAAACATCC
  TGGTTATCCTGGCCGTGGTCAGGAACGGCAACCTGCACTCCCCGATGTACTTCTTTCTCT
  GCAGCCTGGCGGTGGCCGACATGCTGGTAAGTGTGTCCAATGCCCTGGAGACCATCATGA
  TCGCCATCGTCCACAGCGACTACCTGACCTTCGAGGACCAGTTTATCCAGCACATGGACA
  ACATCTTCGACTCCATGATCTGCATCTCCCTGGTGGCCTCCATCTGCAACCTCCTGGCCA
  TCGCCGTCGACAGGTACGTCACCATCTTTTACGCGCTCCGCTACCACAGCATCATGACCG
  TGAGGAAGGCCCTCACCTTGATCGTGGCCATCTGGGTCTGCTGCGGCGTCTGTGGCGTGG
  TGTTCATCGTCTACTCGGAGAGCANAAGGTCATTGTGTGCCTCATCACCATGTTCTTCGC
  CATGATGCTNCTCATGGGCACCCTCTACGTGCACATGTTCCTCTTTGCGCGGCTGCACGT
  CAAGCGCATAGCAGCACTGCCATCTGCCGACCGGGGTGGCCCCACAGCAACACTCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_019888 unedited
  TCTANATNCGACAAGACTTGATATCGGTACCGAGCTCGGATCCACTAGTAACGGCCGCCA
  GTGTGCTGGAATTCGGCTTCTATCCCAAGTTCATGCCGTTGCAGCCACAGAGAATCTCCC
  TAAAGGTGTTGCGCAATTCCAGGCTCCGGAAAGCGTAGATGAGTGGGTCGATGACGGAGT
  TGCACATGATGAGGACCAGGTAGGTGTTGAAGTGGGCAGTGTAGCAGATGCAGTAGGGGT
  TGGTGGGGCAGGTGATGATGAGGACCAGGTGGAGGAAGAAGGGGGCCCAGCAGAAGATGA
  ACACGCCCAGGAGAATGGTGATGGTGACTGCCCCCTTCATGCATGAGTGTTGCTGTGGGG
  CCACCCCGTCGGCAGGTGGCAGTGCTGCTATGCGCTTGACGTGCAGCCGCGCAAAGAGGA
  ACATGTGCACGTAGAGGGTGCCCATGAGGAGCATCATGGCGAAGAACATGGTGATGAGGC
  ACACAATGACCATTTTGCTCTCCGAGTAGACGATGAACACCACGCCACAGACGCCGCAGC
  AGACCCAGATGGCCACGATCAAGGTGAGGGCCTTCCTCACGGTCATGATGCTGTGGTAGC
  GGAGCGCGTAAAAGATGGTGACGTACCTGTCGACGGCGATGGCCAGGATGTTGCAGATGG
  AGGCCACCAGGGAGATGCAGATCATGGAGTCGAAGATGTTGTCCATGTGCTGGATAAACT
  GGTCCTCGAAGGTCAGGTAGTCGCTGTGGACGATGGGCGATCATGATGGTCTCANGGCAT
  TGGACACACTTACCAGCATGTCGGCCACCGCCAGGCTGCAGAGAAAGGAGTACATCGGGG
  GATTGCATGTTGCCC
  
• Restriction Sites: Please inquire
• ACCN: NM_019888
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_019888.2, NP_063941.2
• RefSeq Size: 1083 bp
• RefSeq ORF: 1083 bp
• Locus ID: 4159
• UniProt ID: P41968
• Cytogenetics: 20q13.2
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008]