ALDH8A1 (NM_022568) Human Untagged Clone

CAT#: SC111837

ALDH8A1 (untagged)-Human aldehyde dehydrogenase 8 family, member A1 (ALDH8A1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ALDH8A1
• Synonyms: ALDH12; DJ352A20.2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_022568 edited
  ATGGCTGGAACAAACGCACTTTTGATGCTGGAAAACTTCATAGATGGAAAATTTTTACCT
  TGTAGCTCATATATAGATTCTTACGACCCATCAACAGGGGAAGTGTATTGCAGAGTGCCA
  AATAGTGGAAAAGACGAGATCGAAGCCGCGGTCAAGGCCGCCAGAGAAGCCTTTCCCAGC
  TGGTCATCCCGCAGCCCCCAGGAGCGCTCACGGGTCCTGAACCAGGTGGCGGATTTGCTG
  GAGCAGTCCCTGGAGGAGTTTGCCCAGGCCGAGTCTAAAGACCAAGGGAAAACCTTAGCA
  CTGGCAAGAACCATGGACATTCCCCGGTCTGTGCAGAACTTCAGGTTCTTCGCTTCCTCC
  AGCCTGCACCACACGTCAGAGTGCACGCAGATGGACCACCTGGGCTGCATGCACTACACG
  GTGCGGGCCCCGGTGGGAGTCGCTGGTCTGATCAGCCCCTGGAATTTGCCACTCTACTTG
  CTGACCTGGAAGATAGCTCCAGCGATGGCTGCAGGGAACACTGTGATAGCCAAGCCCAGT
  GAGCTGACTTCAGTGACTGCGTGGATGTTGTGCAAACTCCTGGATAAAGCAGGTGTTCCA
  CCAGGTGTGGTCAATATTGTGTTTGGAACCGGGCCCAGGGTGGGTGAGGCCCTGGTGTCC
  CACCCAGAGGTGCCCCTGATCTCCTTCACCGGGAGCCAGCCCACCGCTGAGCGGATCACC
  CAGCTGAGCGCTCCCCACTGCAAAAAGCTCTCCCTGGAGCTGGGGGGCAAGAATCCTGCC
  ATCATCTTTGAGGACGCCAACCTGGATGAGTGCATTCCGGCAACCGTCAGGTCCAGCTTT
  GCCAACCAGGTCAGAAGTTACGTCAAGAGAGCTCTTGCTGAAGGTGCCCAAATTTGGTGC
  GGTGAGGGAGTGGATAAGTTGAGCCTCCCTGCCAGGAACCAGGCAGGCTACTTTATGCTT
  CCCACGGTGATAACAGACATTAAGGATGAATCCTGCTGCATGACGGAAGAGATATTTGGT
  CCAGTGACGTGTGTCGTCCCCTTTGATAGTGAAGAGGAGGTGATTGAAAGAGCCAACAAC
  GTTAAGTATGGGCTGGCGGCTACCGTGTGGTCCAGCAATGTGGGGCGCGTCCACCGGGTG
  GCTAAGAAGCTGCAGTCTGGCTTGGTCTGGACCAACTGCTGGCTCATCAGGGAGCTGAAC
  CTTCCTTTCGGGGGGATGAAGAGTTCTGGAATAGGTAGAGAGGGAGCCAAGGACTCTTAC
  GACTTCTTCACTGAGATCAAAACCATCACCGTTAAACACTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022568 unedited
  TACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGCTCAGTCGTAAAGAGGAAAGGCA
  GAATTTTTCCTTGCTATGGCTGGAACAAACGCACTTTTGATGCTGGAAAACTTCATAGAT
  GGAAAATTTTTACCTTGTAGCTCATATATAGATTCTTACGACCCATCAACAGGGGAAGTG
  TATTGCAGAGTGCCAAATAGTGGAAAAGACGAGATCGAAGCCGCGGTCAAGGCCGCCAGA
  GAAGCCTTTCCCAGCTGGTCATCCCGCAGCCCCCAGGAGCGCTCACGGGTCCTGAACCAG
  GTGGCGGATTTGCTGGAGCAGTCCCTGGAGGAGTTTGCCCAGGCCGAGTCTAAAGACCAA
  GGGAAAACCTTAGCACTGGCAAGAACCATGGACATTCCCCGGTCTGTGCAGAACTTCAGG
  TTCTTCGCTTCCTCCAGCCTGCACCACACGTCAGAGTGCACGCAGATGGACCACCTGNGC
  TGCATGCACTACACGGTGCGGGCCCCGGTGGGAGTCGCTGGTCTGATCAGCCCCTGGAAT
  TTGCCACTCTACTTGCTGACCTGGAAGATAGCTCCAGCGATGGCTGCAGGGAACACTGTG
  ATAGCCAAGCCCAGTGAGCTGACTTCAGTGACTGCGTGGATGTTGTGCAAACTCCTGGAT
  AAGCAGGTGTTCCACCAGGTGTGGTCAATATTGTGTTTGGAAACCGGCCCAGGGTGGGTG
  ANGCCCTGGTGTCCACCCAGAGTGCCCCTGATCTCCTTCACCGGAGCCAGCCCACGCTGA
  GCGGATCACCAGCTGAGCGCTTCCACTGCAAAAGCTCTCCTGGNAGCTGGGGGCAGAATC
  TGCCATATCTTGAGACGCACCTGGAGAGTGCATTCGGCACCGTCAGTCAGCTTTGCACCA
  GTCAGAATACTCAGAAGCTTGCTGAGTGCCAATTGTGCGGAGGAAGGATATTGACCTCTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_022568 unedited
  GGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTACTAAAATTGCTTAACATT
  TATTGCTTCTTTTGGGGTTAGCAAGTTGTAAGCCTCATTAGATGCATACACTAAGAAATG
  GAATTGATTAGACTCGACCGTAGGAATGGATCAAACTATGTACTCTTCTTGTTCCAAGTT
  TCCTCCAAAAGTAGTAGTTATTTTGTTTTTCTTCATCCTTGTACAGATACATTTAGTAGA
  GCTTACCACATAGCCTTCCCCTAACAAATTCCAAAGACGTCCACAGCCCCCTTATGTAAT
  GAGGTCCAATCAATGATCAATTAGCCATGCTAGTGGCTAATAGACAAGGAGATTATCTCC
  ATAATCTCTCCAAAGATGGCAAATTATGGCTATTTATTTTTGGTTTTGCAGCATTTTTTT
  TTTAAAGACAAGGTCTCACTGTATCCCCCAGGCTGAAATGCAGTGGAATGATCATGGCTC
  ACTGCAGCCTCAACCGCCTGGGCTCAAGCAATCCTCCCACCTCAGCCTCCCAAGTAGCTG
  GGGCTATAGGCAGAGGGCACCACACCAAGCTAATTTTTAAACTTTTGGTAAAGACAGGAT
  TTCACCATGTTGCCTAGGCTGATCTCGAACTCCTGAACTCAAGTGATCCACCCACCTTGG
  CCTCCCAAAGTGCTGGGATTATAGGCATGANGCACTGTGCCTGATTGCATATTTTTTAAA
  ATTTACCANATGAAATAATCTGATTATCTGGAGATTCCCCAGAGCTCAATGAAGATGATG
  NAAGAACACTATGAAAACCATACCTGGGAGGAGCCTGACACTGGCATCATTGGTCTATCT
  TNCCTACTATAAGNCTTTNTTTCCGAGTCCACATGAANATAGACAGTATCTCTTCACTAT
  GGGTAAGCTACTAAGACTGAGGATAGCTANAGATACCTTCTGCAGTCAAGGCTANCTGGA
  ATCTGCCATGATTCTCTACACAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_022568
• Insert Size: 2460 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_022568.2, NP_072090.1
• RefSeq Size: 2549 bp
• RefSeq ORF: 1464 bp
• Locus ID: 64577
• UniProt ID: Q9H2A2
• Cytogenetics: 6q23.3
• Domains: aldedh
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the aldehyde dehydrogenase family of proteins. The encoded protein has been implicated in the synthesis of 9-cis-retinoic acid and in the breakdown of the amino acid tryptophan. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. In addition, this enzyme has been shown to catalyze the conversion of 2-aminomuconic semialdehyde to 2-aminomuconate in the kynurenine pathway of tryptophan catabolism. [provided by RefSeq, Jul 2018]
  Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer protein (isoform 1).