Gastric Inhibitory Polypeptide Receptor (GIPR) (NM_000164) Human Untagged Clone

CAT#: SC110906

GIPR (untagged)-Human gastric inhibitory polypeptide receptor (GIPR)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Gastric Inhibitory Polypeptide Receptor
• Synonyms: PGQTL2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000164, RT-PCR generated
  ATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTC
  CAGAGGGCGGAGACAGGCTCTAAGGGGCAGACGGCGGGGGAGCTGTACCAGCGCTGGGAA
  CGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGGCCTCGCC
  TGTAACGGGTCCTTCGATATGTACGTCTGCTGGGACTATGCTGCACCCAATGCCACTGCC
  CGTGCGTCCTGCCCCTGGTACCTGCCCTGGCACCACCATGTGGCTGCAGGTTTCGTCCTC
  CGCCAGTGTGGCAGTGATGGCCAATGGGGACTTTGGAGAGACCATACACAATGTGAGAAC
  CCAGAGAAGAATGAGGCCTTTCTGGACCAAAGGCTCATCTTGGAGCGGTTGCAGGTCATG
  TACACTGTCGGCTACTCCCTGTCTCTCGCCACACTGCTGCTAGCCCTGCTCATCTTGAGT
  TTGTTCAGGCGGCTACATTGCACTAGAAACTATATCCACATCAACCTGTTCACGTCTTTC
  ATGCTGCGAGCTGCGGCCATTCTCAGCCGAGACCGTCTGCTACCTCGACCTGGCCCCTAC
  CTTGGGGACCAGGCCCTTGCGCTGTGGAACCAGGCCCTCGCTGCCTGCCGCACGGCCCAG
  ATCGTGACCCAGTACTGCGTGGGTGCCAACTACACGTGGCTGCTGGTGGAGGGCGTCTAC
  CTGCACAGTCTCCTGGTGCTCGTGGGAGGCTCCGACGAGGGCCACTTCCGCTACTACCTG
  CTCCTCGGCTGGGGGGCCCCCGCGCTTTTCGTCATTCCCTGGGTGATCGTCAGGTACCTG
  TACGAGAACACGCAGTGCTGGGAGCGCAACGAAGTCAAGGCCATTTGGTGGATTATACGG
  ACCCCCATCCTCATGACCATCTTGATTAATTTCCTCATTTTTATCCGCATTCTTGGCATT
  CTCCTGTCCAAGCTGAGGACACGGCAAATGCGCTGCCGGGATTACCGGCTGAGGCTGGCT
  CGCTCCACGCTGACGCTGGTGCCCCTGCTGGGTGTCCACGAGGTGGTGTTTGCTCCCGTG
  ACAGAGGAACAGGCCCGGGGCGCCCTGCGCTTCGCCAAGCTCGGCTTTGAGATCTTCCTC
  AGCTCCTTCCAGGGCTTCCTGGTCAGCGTCCTCTACTGCTTCATCAACAAGGAGGTGCAG
  TCGGAGATCCGCCGTGGCTGGCACCACTGCCGCCTGCGCCGCAGCCTGGGCGAGGAGCAA
  CGCCAGCTCCTGGAGCGCGCCTTCCGGGCCCTGCCCTCCGGCTCCGGCCCGGGCGAGGTC
  CCCACCAGCCGCGGCTTGTCCTCGGGGACCCTCCCAGGGCCTGGGAATGAGGCCAGCCGG
  GAGTTGGAAAGTTACTGCTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000164 unedited
  NGTAACGTTCGAAATTTGTATACGACTCACTATAGGCGGCCGCCAGTGTGATGGATATCT
  GCAGAATTCGGCTTGATCCTCACGATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGG
  CTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAGACGGCG
  GGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCC
  GCGGAACCGCCTTCAGGCCTCGCCTGTAACGGGTCCTTCGATATGTACGTCTGCTGGGAC
  TATGCTGCACCCAATGCCACTGCCCGTGCGTCCTGCCCCTGGTACCTGCCCTGGCACCAC
  CATGTGGCTGCAGGTTTCGTCCTCCGCCAGTGTGGCAGTGATGGCCAATGGGGACTTTGG
  AGAGACCATACACAATGTGAGAACCCAGAGAAGAATGAGGCCTTTCTGGACCAAAGGCTC
  ATCTTGGAGCGGTTGCAGGTCATGTACACTGTCGGCTACTCCCTGTCTCTCGCCACACTG
  CTGCTAGCCCTGCTCATCTTGAGTTTGTTCAGGCGGCTACATTGCACTAGAAACTATATC
  CACATCAACCTGTTCACGTCTTTCATGCTGCGAGCTGCGGCCATTCTCAGCCGAGACCGT
  CTGCTACCTCGACCTGGCCCCTACCTTGGGGACCAGGCCCTTGCGCTGTGGAACCAGGCC
  CTCGCTGCCTGGCGCACGGCCCAGATCGTGACCCAGTACTGCGTGGGTGCCAACTACACG
  TGGCTGCTGGTGGAGGGCGTCTACCTGCACAGTCTTCTGGTGCTCGTGGGGAGCTCCGAC
  GAGGGCCACTTTCGCTACTACCTGCTNCTCGGCTGGGGGGCCCCCGCGCTTTTCGTCATT
  CCTGGGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000164 unedited
  CGTTCGGCACATTGGCGATGGCCAACTTCCAGGCCAGGGAAGAGCATGGGGAAGGGGTCA
  CAGGGCATGCCACCCGGGTATCTGTTCAGGCAAACAGCTATGCACCGCGGCCCGCAATCT
  AGAGTCGACAAGCTTGATATCGGTACCGAGCTCGGATCCACTAGTAACGGCCGCCAGTGT
  GCTGGAATTCGGCTTCCCTAGCAGTAACTTTCCAACTCCCGGCTGGCCTCATTCCCAGGC
  CCTGGGAGGGTCCCCGAGGACAAGCCGCGGCTGGTGGGGACCTCGCCCGGGCCGGAGCCG
  GAGGGCAGGGCCCGGAAGGCGCGCTCCAGGAGCTGGCGTTGCTCCTCGCCCAGGCTGCGG
  CGCAGGCGGCAGTGGTGCCAGCCACGGCGGATCTCCGACTGCACCTCCTTGTTGATGAAG
  CAGTAGAGGACGCTGACCAGGAAGCCCTGGAAGGAGCTGAGGAAGATCTCAAAGCCGAGC
  TTGGCGAAGCGCAGGGCGCCCCGGGCCTGTTCCTCTGTCACGGGAGCAAACACCACCTCG
  TGGACACCCAGCAGGGGCACCAGCGTCAGCGTGGAGCGAGCCAGCCTCAGCCGGTAATCC
  CGGCAGCGCATTTGCCGTGTCCTCAGCTTGGACAGGAGAATGCCAAGAATGCGGATAAAA
  ATGAGGAAATTAATCAAGATGGTCATGAGGATGGGNGGTCCGTATAATCCACCAAATGGC
  CTTGACTTCGTTGCGCTCCCAGCACTGCGTGTTCTCGTACAGGTACCTGACGATCACCCA
  GGGAATGACGAANAGCGCGGGGGCCCCCCCAGCCGAGAGCATGTAGTAGCGGNAAGTGGG
  CCCTCGTCGGAGCCTCCCACGAGCACCAGNAGACTGTGCATGTAGACGCCCTCCACCACA
  CCAGTTGTAGTCGC
  
• Restriction Sites: Please inquire
• ACCN: NM_000164
• Insert Size: 1700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000164.2, NP_000155.1
• RefSeq Size: 2024 bp
• RefSeq ORF: 1401 bp
• Locus ID: 2696
• UniProt ID: P48546
• Cytogenetics: 19q13.32
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.