IL16 (NM_004513) Human Untagged Clone

CAT#: SC109345

IL16 (untagged)-Human interleukin 16 (lymphocyte chemoattractant factor) (IL16), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL16
• Synonyms: LCF; NIL16; prIL-16; PRIL16
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109345 sequence for NM_004513 edited (data generated by NextGen Sequencing)
  ATGGACTATAGCTTTGATACCACAGCCGAAGACCCTTGGGTTAGGATTTCTGACTGCATC
  AAAAACTTATTTAGCCCCATCATGAGTGAGAACCATGGCCACATGCCTCTACAGCCCAAT
  GCCAGCCTGAATGAAGAAGAAGGGACACAGGGCCACCCAGATGGGACCCCACCAAAGCTG
  GACACCGCCAATGGCACTCCCAAAGTTTACAAGTCAGCAGACAGCAGCACTGTGAAGAAA
  GGTCCTCCTGTGGCTCCCAAGCCAGCCTGGTTTCGCCAAAGCTTGAAAGGTTTGAGGAAT
  CGTGCTTCAGACCCAAGAGGGCTCCCTGATCCTGCCTTGTCCACCCAGCCAGCACCTGCT
  TCCAGGGAGCACCTAGGATCACACATCCGGGCCTCCTCCTCCTCCTCCTCCATCAGGCAG
  AGAATCAGCTCCTTTGAAACCTTTGGCTCCTCTCAACTGCCTGACAAAGGAGCCCAGAGA
  CTGAGCCTCCAGCCCTCCTCTGGGGAGGCAGCAAAACCTCTTGGGAAGCATGAGGAAGGA
  CGGTTTTCTGGACTCTTGGGGCGAGGGGCTGCACCCACTCTTGTGCCCCAGCAGCCTGAG
  CAAGTACTGTCCTCGGGGTCCCCTGCAGCCTCCGAGGCCAGAGACCCAGGTGTGTCTGAG
  TCCCCTCCCCCAGGGCGGCAGCCCAATCAGAAAACTCTCCCCCCTGGCCCGGACCCGCTC
  CTAAGGCTGCTGTCAACACAGGCTGAGGAATCTCAAGGCCCAGTGCTCAAGATGCCTAGC
  CAGCGAGCACGGAGCTTCCCCCTGACCAGGTCCCAGTCCTGTGAGACGAAGCTACTTGAC
  GAAAAGACCAGCAAACTCTATTCTATCAGCAGCCAAGTGTCATCGGCTGTCATGAAATCC
  TTGCTGTGCCTTCCATCTTCTATCTCCTGTGCCCAGACTCCCTGCATCCCCAAGGAAGGG
  GCATCTCCAACATCATCATCCAACGAAGACTCAGCTGCAAATGGTTCTGCTGAAACATCT
  GCCTTGGACACAGGGTTCTCGCTCAACCTTTCAGAGCTGAGAGAATATACAGAGGGTCTC
  ACGGAAGCCAAGGAAGACGATGATGGGGACCACAGTTCCCTTCAGTCTGGTCAGTCCGTT
  ATCTCCCTGCTGAGCTCAGAAGAATTAAAAAAACTCATCGAGGAGGTGAAGGTTCTGGAT
  GAAGCAACATTAAAGCAATTAGACGGCATCCATGTCACCATCTTACACAAGGAGGAAGGT
  GCTGGTCTTGGGTTCAGCTTGGCAGGAGGAGCAGATCTAGAAAACAAGGTGATTACGGTT
  CACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAG
  GTTCTTTCCATCAACGGCAAGTCTCTCAAGGGGACCACGCACCATGATGCCTTGGCCATC
  CTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACTCCAGAG
  GCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGAT
  GTTTCTGTAGAATCTACAGCAGAGGCCACAGTCTGCACGGTGACACTGGAGAAGATGTCG
  GCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAGCCTCTC
  ACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGA
  GATGAAATCTTGCAGCTGGGTGGCACTGCCATGCAGGGCCTCACACGGTTTGAAGCCTGG
  AACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAAAGCCTC
  CAGTCCAAGGAAACCACAGCTGCTGGAGACTCCTAG
  
  Clone variation with respect to NM_004513.5
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004513 unedited
  GTATTTTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGGGGAAGACAC
  AGCAGGGAGAAGCCCTAGTGCCTCTGCCGGCTGCCCAGGACCTGGTATCGGCCCACAGAC
  CAAGTCCTCCACAGAGGGCGAGCCAGGGTGGAGAAGAGCCAGCCCAGTGACCCAAACATC
  CCCGATAAAACACCCACTGCTTAAGAGGCAGGCTCGGATGGACTATAGCTTTGATACCAC
  AGCCGAAGACCCTTGGGTTAGGATTTCTGACTGCATCAAAAACTTATTTAGCCCCATCAT
  GAGTGAGAACCATGGCCACATGCCTCTACAGCCCAATGCCAGCCTGAATGAAGAAGAAGG
  GACACAGGGCCACCCAGATGGGACCCCACCAAAGCTGGACACCGCCAATGGCACTCCCAA
  AGTTTACAAGTCAGCAGACAGCAGCACTGTGAAGAAAGGTCCTCCTGTGGCTCCCAAGCC
  AGCCTGGTTTCGCCAAAGCTTGAAAGGTTTGAGGAATCGTGCTTCAGACCCAAGAGGGCT
  CCCTGATCCTGCCTTGTCCACCCAGCCAGCACCTGCTTCCAGGGAGCACCTAGGATCACA
  CATCCGGGCCTCCTCCTCCTCCTCCTCCATCAGGCAGAGAATCAGCTCCTTTGAAACCTT
  TGGCTCCTCTCAACTGCCTGACAAAGGAGCCCAGAGACTGAGCCTCCAGCCCTCCTCTGG
  GGAGGCAGCAAAACCTCTTGGGAAGCATGAGGAAGGACGGTTTTCTGGACTCTTGNGGCG
  AGGGGCTGCACCCACTCTTGTGCCCCAGCAGCCTGAGCAAGTACTGTCCTCGGNGTCCCC
  TGCAGCCTNNCGAGCCAGAGACCCAGGTGTGTCTGAGTCCCCTCCCCAGGGCGCAGCCCA
  TCAGAAACTCTCCCCCTGCCCGACCGCTCTAAGCTGTGTCACCAGCTGAGGACTCAAGCC
  ATGCTCAGAGCCTAGCACG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004513 unedited
  AACTTTATACCTATTTTATTGTGGCACCACAATATTATCATTAAGCTCTCTTTTTACACA
  GTCTGCAATTTGTATCAGCTGCCCCCGTGTGACTCTGCCCTTATTTTAAGGAACAACCTT
  TTGCTGGGTGGCGTCCTANAAGGTCTGGGCCTGGGCAGCAGCCACTGGGAAGCCCACCTG
  TGCTTTCCCCCATCTGGGTGGGGCGGCAGCAGAGACCCTGAGAATCAGCGGTTATGGGAG
  CTGTGTGTTAGCTGTGTGTTATTGGCTTTGGCTTCAGCATGTCCTGCCTAGGAGTCTCCA
  GCAGCTGTGGTTTCCTTGGACTGGAGGCTTTTTCTCCTGATGACAATCGTGACAGGTCCA
  TCAGGCAGTGCCTTGATGATGTTCCAGGCTTCAAACCGTGTGAGGCCCTGCATGGCAGTG
  CCACCCAGCTGCAAGATTTCATCTCCAGGCTGGACTGTCTCACTTTGTTCTGAGGCTGCT
  CCTTTGAAAATCCTGTTAATGGTGAGAGGCTTGTCTCCGTGTAGGGAGCCCTTCCCTCCT
  TCCAGGCTGAAGCCCAGCCCTGCCGACATCTTCTCCAGTGTCACCGTGCAGACTGTGGCC
  TCTGCTGTAGATTCTACAGAAACATCACTGGCTGCAGAGGCTGAGGCTGCAGAGTCAGTG
  GAGGAGTTGAGGTCGGGCATGGCCTCTGGAGTCAGCTTCCTTGTGACAATCACAGCTTGC
  CTGNGCTCTCGAGCTTGGCGNGAGATGGCCAAGGCATCATGGTGCGTGGTCCCCTTGAGA
  GACTTGCCGTTGATGGAAAGAACCTCATTGCCCTTNCTGATAGTCCCTTCCTGGGGAGCC
  AGCCCATTTGGAAACACTCTGTGAACCGTAATCACNNCTGTTTCTAGATCTGCTCCTNCT
  GCCAAGCTGAACCCAAGACCAGCACCTTNCTCCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004513
• Insert Size: 2650 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004513.3, NP_004504.3
• RefSeq Size: 6193 bp
• RefSeq ORF: 1896 bp
• Locus ID: 3603
• UniProt ID: Q14005
• Cytogenetics: 15q25.1
• Domains: PDZ
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
  Transcript Variant: This variant (1) encodes isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.