GNAL (NM_182978) Human Untagged Clone

CAT#: SC107605

GNAL (untagged)-Human guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (GNAL), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GNAL
• Synonyms: DYT25
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_182978, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGTCTGTGCTACAGTCTGCGGCCGCTGCTTTTCGGGGGCCCAGGGGACGACCCCTGCGCGGCCTCGG
  AGCCGCCGGTGGAGGACGCGCAGCCCGCCCCGGCCCCGGCCCTGGCCCCAGTCCGGGCGGCCGCAAGGGA
  CACGGCCCGGACCCTGCTCCCTCGGGGCGGCGAAGGGAGCCCGGCATGCGCTCGGCCCAAAGCAGACAAG
  CCGAAGGAGAAGCGGCAGCGCACCGAGCAGCTGAGTGCCGAGGAGCGCGAGGCGGCCAAGGAGCGCGAGG
  CGGTCAAGGAGGCGAGGAAAGTGAGCCGGGGCATCGACCGCATGCTGCGCGACCAGAAGCGCGACCTGCA
  GCAGACGCACCGGCTCCTGCTGCTCGGGGCTGGTGAGTCTGGGAAAAGCACTATCGTCAAACAGATGAGG
  ATCCTGCACGTCAATGGGTTTAATCCCGAGGAAAAGAAACAGAAAATTCTGGACATCCGGAAAAATGTTA
  AAGATGCTATCGTGACAATTGTTTCAGCAATGAGTACTATAATACCTCCAGTTCCGCTGGCCAACCCTGA
  AAACCAATTTCGATCAGACTACATCAAGAGCATAGCCCCTATCACTGACTTTGAATATTCCCAGGAATTC
  TTTGACCATGTGAAAAAACTTTGGGACGATGAAGGCGTGAAGGCATGCTTTGAGAGATCCAACGAATACC
  AGCTGATTGACTGTGCACAATACTTCCTGGAAAGAATCGACAGCGTCAGCTTGGTTGACTACACACCCAC
  AGACCAGGACCTCCTCAGATGCAGAGTTCTGACATCTGGGATTTTTGAGACACGATTCCAAGTGGACAAA
  GTAAACTTCCACATGTTTGATGTTGGTGGCCAGAGGGATGAGAGGAGAAAATGGATCCAGTGCTTTAACG
  ATGTCACAGCTATCATTTACGTCGCAGCCTGCAGTAGCTACAACATGGTGATTCGAGAAGATAACAACAC
  CAACAGGCTGAGAGAGTCCCTGGATCTTTTTGAAAGCATCTGGAACAACAGGTGGTTACGGACCATTTCT
  ATCATCTTGTTCTTGAACAAACAAGATATGCTGGCAGAAAAAGTCTTGGCAGGGAAATCAAAAATTGAAG
  ACTATTTCCCAGAATATGCAAATTATACTGTTCCTGAAGACGCAACACCAGATGCAGGAGAAGATCCCAA
  AGTTACAAGAGCCAAGTTCTTTATCCGGGACCTGTTTTTGAGGATCAGCACGGCCACCGGTGACGGCAAA
  CATTACTGCTACCCGCACTTCACCTGCGCCGTGGACACAGAGAACATCCGCAGGGTGTTCAACGACTGCC
  GCGACATCATCCAGCGGATGCACCTCAAGCAGTATGAGCTCTTGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_182978 unedited
  TACTATAGGGCGGCCGCGAATTCGCACGAGGGGGCAGTGAGGGGCTGTGGCCCTCGGCCC
  CGGCCTGCCGCACCCCCTTCCCGCAGCTGGCGGCCGGCAGCGCCGAACAGGGTCCGGGTG
  CAGCCCCCTCCCGCCCCTCCGCTGAGGCGCCGGCCTGAACTGGGCGCGGGAACCAGGCCG
  CCCTCGGCGCCCAGCCTGCCCTAGTCCCGCGCGCCGCCCCCGCTGTGCCGCGCCCACATG
  GGTCTGTGCTACAGTCTGCGGCCGCTGCTTTTCGGGGGCCCAGGGGACGACCCCTGCGCG
  GCCTCGGAGCCGCCGGTGGAGGACGCGCAGCCCGCCCCGGCCCCGGCCCTGGCCCCAGTC
  CGGGCGGCCGCAAGGGACACGGCCCGGACCCTGCTCCCTCGGNGCGGCGAAGGGAGCCCG
  GCATGCGCTCGGCCCAAAGCAGACAAGCCGAAGGAGAAGCGGCAGCGCACCGAGCANCTG
  AGTGCCGAGGAGCGCGAGGCGGCCAANGAGCGCGAGGCGGTCAAGGAGGCGAGGAAAGTG
  AGCCGGNGCATCGACCGCATGCTGCGCGACCAGAAGCGCGACCTGCAGCAGACGCACCGG
  CTCCTGCTGCTCGGGGCTGGGTGAGTCTGGGAAAAGCACTATCGTCAACAGATGAAGATC
  CTGCACGTCAATGGGTTTTATCCCGAGGAAAAGAACANGAAATTCTGGACATCCGGNAAA
  ATGGTAAGATGCTATCGTGACAANTGGTTCAGCNATGAGTACTATTATACCTCCCAGTTN
  CCGCTGGCCACCCCTGAAACCAATTNCGATCAGACTACTCAAGAGCATAGCCCCATCACT
  GACTTTGGAATTCCCAGGAATCCTTGGACTGTGAAAAAACTTGGACAAAAAAAGCCGTAA
  GGCTGCTTTTNAAAAACCAACAAACCACCTGATTGACTGGGCCAAACTTCTGGAAGATAA
  AAGGCACCCTTGGGTGCTAACCCCCAACAGACCTNNNGGGAAGAGTTGTTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_182978
• Insert Size: 4300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_182978.1, NP_892023.1
• RefSeq Size: 2479 bp
• RefSeq ORF: 1377 bp
• Locus ID: 2774
• UniProt ID: P38405
• Cytogenetics: 18p11.21
• Protein Families: Druggable Genome
• Protein Pathways: Calcium signaling pathway, Olfactory transduction
• Gene Summary: This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.