TRIM37 (NM_015294) Human Untagged Clone

CAT#: SC102603

TRIM37 (untagged)-Human tripartite motif containing 37 (TRIM37), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRIM37
• Synonyms: MUL; POB1; TEF3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015294 edited
  GAATTCGGCACGAGGGGGCGCCGGGCTTTTATCGGCGATTTGATCTGGCGACCTCGGGCC
  GGCGCCTAAGAGGTCAGACTGCGGAGCCTGCGGGTCGCCAGCGGCCCCGCCGAGAGCCGG
  AGGCAATGGATGAACAGAGCGTGGAGAGCATTGCTGAGGTTTTCCGATGTTTCATTTGTA
  TGGAGAAATTGCGGGATGCACGCCTGTGTCCTCATTGCTCCAAACTGTGTTGTTTCAGCT
  GTATTAGGCGCTGGCTGACAGAGCAGAGAGCTCAATGTCCTCATTGCCGTGCTCCACTCC
  AGCTACGAGAACTAGTAAATTGTCGTTGGGCAGAAGAAGTAACACAACAGCTTGATACTC
  TTCAACTCTGCAGTCTCACCAAACATGAAGAAAATGAAAAGGACAAATGTGAAAATCACC
  ATGAAAAACTTAGTGTATTTTGCTGGACTTGTAAGAAGTGTATCTGCCATCAGTGTGCAC
  TTTGGGGAGGAATGCATGGCGGACATACCTTTAAACCTTTGGCAGAAATTTATGAGCAAC
  ACGTCACTAAAGTGAATGAAGAGGTAGCCAAACTTCGTCGGCGTCTCATGGAACTGATCA
  GCTTAGTTCAAGAAGTGGAAAGGAATGTAGAAGCTGTAAGAAATGCAAAAGATGAGCGTG
  TTCGGGAAATTAGGAATGCAGTGGAGATGATGATTGCACGGTTAGACACACAGCTGAAGA
  ATAAGCTTATAACACTGATGGGTCAGAAGACATCTCTAACCCAAGAAACAGAGCTTTTGG
  AATCCTTACTTCAGGAGGTGGAGCACCAGTTGCGGTCTTGTAGTAAGAGTGAGTTGATAT
  CTAAGAGCTCAGAGATCCTTATGATGTTTCAGCAAGTTCATCGGAAGCCCATGGCATCTT
  TTGTTACCACTCCTGTTCCACCAGACTTTACCAGTGAATTAGTGCCATCTTACGATTCAG
  CTACTTTTGTTTTAGAGAATTTCAGCACTTTGCGTCAGAGAGCAGATCCTGTTTACAGTC
  CACCTCTTCAAGTTTCAGGACTTTGCTGGAGGTTAAAAGTTTACCCAGATGGAAATGGAG
  TTGTGCGAGGTTACTACTTATCTGTGTTTCTGGAGCTCTCAGCTGGCTTGCCTGAAACTT
  CTAAATATGAATATCGTGTAGAGATGGTTCACCAGTCCTGTAATGATCCTACAAAAAATA
  TCATTCGAGAATTTGCATCTGACTTTGAAGTTGGAGAATGCTGGGGCTATAATAGATTTT
  TCCGTTTGGACTTACTCGCAAATGAAGGATACTTGAATCCACAAAATGATACAGTGATTT
  TAAGGTTTCAGGTACGTTCACCAACTTTCTTTCAAAAATCCCGGGACCAGCATTGGTACA
  TTACTCAGTTGGAAGCTGCACAGACTAGTTATATCCAACAAATAAACAACCTTAAAGAGC
  ACGAGCTTTCAGATGGAGATCTGGATCTGGATCTTGTTTATGAGGATGAAGTAAATCAGC
  TCGATGGCAGCAGTTCCTCTGCTAGTTCCACAGCAACAAGTAATACAGAAGAAAATGATA
  TTGATGAAGAAACTATGTCTGGAGAAAATGATGTGGAATATAACAACATGGAATTAGAAG
  AGGGAGAACTCATGGAAGATGCAGCTGCTGCAGGACCCGCAGGTAGTAGCCATGGTTATG
  TGGGTTCCAGTAGTAGAATATCAAGAAGAACACATTTATGCTCCGCTGCTACCAGTAGTT
  TACTAGACATTGATCCATTAATTTTAATACATTTGTTGGACCTTAAGGACCGGAGCAGTA
  TAGAAAATTTGTGGGGCTTACAGCCTCGCCCACCTGCTTCACTTCTGCAGCCCACAGCAT
  CATATTCTCGAAAAGATAAAGACCAAAGGAAGCAACAGGCAATGTGGCGAGTGCCCTCTG
  ATTTAAAGATGCTAAAAAGACTCAAAACTCAAATGGCCGAAGTTCGATGTATGAAAACTG
  ATGTAAAGAATACACTTTCAGAAATAAAAAGCAGCAGTGCTGCTTCTGGAGACATGCAGA
  CAAGCCTTTTTTCTGCTGACCAGGCAGCTCTGGCTGCATGTGGAACTGAAAACTCTGGCA
  GATTGCAGGATTTGGGAATGGAACTCCTGGCAAAGTCATCAGTTGCCAATTGTTACATAC
  GAAACTCCACAAATAAGAAGAGTAATTCGCCCAAGCCAGCTCGATCCAGTGTAGCAGGTA
  GTCTATCACTTCGAAGAGCAGTGGACCCTGGAGAAAATAGTCGTTCAAAGGGAGACTGTC
  AGACTCTGTCTGAAGGCTCCCCAGGAAGCTCTCAGTCTGGGAGCAGGCACAGTTCTCCCC
  GAGCCTTGATACATGGCAGTATCGGTGATATTCTGCCAAAAACTGAAGACCGGCAGTGTA
  AAGCTTTGGATTCAGATGCTGTTGTGGTTGCAGTTTTCAGTGGCTTGCCTGCGGTTGAGA
  AAAGGAGGAAAATGGTCACCTTGGGGGCTAATGCTAAAGGAGGTCATCTGGAAGGACTGC
  AGATGACTGATTTGGAAAATAATTCTGAAACTGGAGAGTTACAGCCTGTACTACCTGAAG
  GAGCTTCAGCTGCCCCTGAAGAAGGAATGAGTAGCGACAGTGACATTGAATGTGACACTG
  AGAATGAGGAGCAGGAAGAGCATACCAGTGTGGGCGGGTTTCACGACTCCTTCATGGTCA
  TGACACAGCCCCCGGATGAAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCC
  CTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGGTAATTGCCAAATCAAGAGA
  ACTGACTTGCAAGCTACCTTGACCCTGAATTTTGCTGTAGTTGGTGCTCAAATTTGTCAT
  CAGTCAGATAATCAGATTTGGTCTTATTTCTTCATTATCTCGACCTGAAATAGTAATTTG
  GAAACTGTTGGAAGGTGGCACAGTTTAGTCTAAGACAGCAGTAGTACATGGGAAAAACAG
  TATGGGAAGAGTTCTTTGTAATGTAAGGAAATAACAATGTAGTTCTCTATTAATTTAGCA
  AATTTGTACATTCACAAAAGGCAGTTTGTCTACTACAGCAGAAGGCTGGTTAACTGCCAG
  AAAATGTACCTCCAGGCCCTGCATGCCGTCAGTAACCCGCCCGGCATTGGTGCTCTACTG
  TCTTTGGCTAGAGCTTAGTTGTGTTTAAATAATCATCTTTATATTTGGGGTTTTAATTAC
  AGTTCCATTAGTGCCTGTAGATTAGTGAACAGAAAATTGCTTTGGAAGAGATTCTGCCCT
  GTAGACACTATGTGAATAACTGAAGTAACACTAGACTGAATCTCCTTTTTGGAGTATGTA
  TCTTCTCTCACTTGTTCAAGTACAGGCACACTGTTCAACCGCATGGTATCTTTCTGTTGT
  GTGACTTCTACAAATGTAATTTTAAATGAAATTAAGTTAACATGGATTCATTACGTTCCT
  GGCCCTGTAGACACGTGTAAGATTATTTAAAATTCTTTCATTTTTTTCTGCCTCTTACTA
  TACGACTGTAGTGCAACAAATATTTTAAAGCCCCCTTTTCTTCTTTATTTTCATTAGTTG
  TACATTGATTTCAGTGTCAACACATTTAAAGATTCATTCATGTTGCACAGTGGCTTACAT
  GAACGTGAAACTGTGATATAAGGTTTTCTTTCATACTCATAATTAGCCCAAAACAGTTGC
  CAAACTTTGCCATTGTGCTCCTGCATTTGTGTTTGAGCTGCTATATATTTGTGGAAATTA
  CACTGAAAGTTGACTAAGAGACTATTGAAAAAGCATGAATAATTAAATATACATGTGAGA
  GACATCTCATCTGCTGTATTTTACTTAGTGAATATTGTTCACTCTTCCGTGTCTGATGTC
  TTGCTGAATGCTGTGACTCATAGTTTACTTTTGTTCAAAATAGTTTGCACTTTTTGTTAA
  TAAAATCAACTTGAGAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015294 unedited
  AGTATTTTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGGGCGCCGGG
  CTTTTATCGGCGATTTGATCTGGCGACCTCGGGCCGGCGCCTAAGAGGTCAGACTGCGGA
  GCCTGCGGGTCGCCAGCGGCCCCGCCGAGAGCCGGAGGCAATGGATGAACAGAGCGTGGA
  GAGCATTGCTGAGGTTTTCCGATGTTTCATTTGTATGGAGAAATTGCGGGATGCACGCCT
  GTGTCCTCATTGCTCCAAACTGTGTTGTTTCAGCTGTATTAGGCGCTGGCTGACAGAGCA
  GAGAGCTCAATGTCCTCATTGCCGTGCTCCACTCCAGCTACGAGAACTAGTAAATTGTCG
  TTGGGCAGAAGAAGTAACACAACAGCTTGATACTCTTCAACTCTGCAGTCTCACCAAACA
  TGAAGAAAATGAAAAGGACAAATGTGAAAATCACCATGAAAAACTTAGTGTATTTTGCTG
  GACTTGTAAGAAGTGTATCTGCCATCAGTGTGCACTTTGGGGAGGAATGCATGGCGGACA
  TACCTTTAAACCTTTGGCAGAAATTTATGAGCAACACGTCACTAAAGTGAATGAAGAGGT
  AGCCAAACTTCGTCGGCGTCTCATGGAACTGATCAGCTTAGTTCAAGAAGTGGAAAGGAA
  TGTAGAAGCTGTAAGAAATGCAAAAGATGAGCGTGTTCGGGAAATTANGAATGCAGTGGA
  GATGATGATTGCACGGTTAGACACACAGCTGAAGAATAAGCTTATAACACTGATGGGTCA
  GAAGACATCTCTAACCCAAGAAACAGAGCTTTTGGAATCCTTACTTCANNGAGTGGAGCA
  CCAGNTGCGGTCTTTGTAGTAGAGTGAGTTGATATCTAAGAGCTCAGAGATCTTTATGAT
  GNTTCAGCAAGTTCATCGGNAAGCCATGGCATCTTTTGNTACCACTCCTGTTNCACCAGA
  CTTTACAGTGAATNATGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015294 unedited
  NNNTTTTGCTTTGGACCCGCGGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTCT
  CAGTTGATTTTATTAACAAAAAGTGCAAACTATTTTGAACAAAAGTAAACTATGAGTCAC
  AGCATTCAGCAAGACATCAGACACGGAAGAGTGAACAATATTCACTAAGTAAAATACAGC
  AGATGAGATGTCTCTCACATGTATATTTAATTATTCATGCTTTTTCAATAGTCTCTTAGT
  CAACTTTCAGTGTAATTTCCACAAATATATAGCAGCTCAAACACAAATGCAGGAGCACAA
  TGGCAAAGTTTGGCAACTGTTTTGGGCTAATTATGAGTATGAAAGAAAACCTTATATCAC
  AGTTTCACGTTCATGTAAGCCACTGTGCAACATGAATGAATCTTTAAATGTGTTGACACT
  GAAATCAATGTACAACTAATGAAAATAAAGAAGAAAAGGGGGCTTTAAAATATTTGTTGC
  ACTACAGTCGTATAGTAAGAGGCAGAAAAAAATGAAAGAATTTTAAATAATCTTACACGT
  GTCTACAGGGCCAGGAACGTAATGAATCCATGTTAACTTAATTTCATTTAAAATTACATT
  TGTAGAAGTCACACAACAGAAAGATACCATGCGGTTGAACAGTGTGCCTGTACTTGAACA
  AGTGAGAGAAGATACATACTCCAAAAAGGAGATTCAGTCTAGTGTTACTTCAGTTATTCA
  CATAGTGTCTACAGGGCAGAATCTCTTCCAAAGCAATTTTCTGTTCACTAATCTACAGGC
  ACTAATGGAAACTGTATTAAAACCCCAAATATAAAGATGATTATTTAAACACAACTAAGC
  TCTAGCCAAAGACAGTAGAGCACCCATGCCNGGGCGGNNTACTGACGGGCATGCAGGCCC
  TGGAGGTACATTTNCTGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015294
• Insert Size: 3800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_015294.2, NP_056109.1
• RefSeq Size: 4488 bp
• RefSeq ORF: 2895 bp
• Locus ID: 4591
• UniProt ID: O94972
• Cytogenetics: 17q22
• Domains: zf-B_box, MATH, BBC
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. Mutations in this gene are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. TRIM37 localizes in peroxisomal membranes, and has been implicated in human peroxisomal biogenesis disorders. [provided by RefSeq, Jul 2020]
  Transcript Variant: This variant (1) and variant 2 encode the same isoform (a).