HIP1R (NM_001303097) Human Tagged ORF Clone

CAT#: RG239106

HIP1R (tGFP-tagged) - Human huntingtin interacting protein 1 related (HIP1R), transcript variant 2

Product Images

Circular map for RG239106

Specifications

Product Data

• Tag: TurboGFP
• Symbol: HIP1R
• Synonyms: HIP3; HIP12; ILWEQ
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG239106 representing NM_001303097.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGAACAGCATCAAGAACGTGCCGGCGCGGGTGCTGAGCCGCAGGCCGGGCCACAGCCTGGAGGCCGAG
  CGCGAGCAGTTCGACAAGACCCAGGCCATCAGCATCAGCAAAGCCATCAACACCCAGGAGGCCCCCGTG
  AAGGAGAAGCACGCCCGGCGCATCATTCTGGGCACACACCACGAGAAGGGGGCTTTCACCTTCTGGTCC
  TACGCCATTGGGCTGCCGCTGCCCAGCAGCTCCATTCTCAGCTGGAAGTTCTGCCACGTCCTCCACAAG
  GTCCTTCGAGACGGGCACCCCAATGTGCTGCATGACTGCCAGCGGTACCGCAGCAACATCCGGGAGATT
  GGAGACCTGTGGGGACATTTGCATGACCGCTACGGACAGCTGGTGAATGTCTACACCAAGCTGCTGCTG
  ACCAAGATCTCCTTCCACCTCAAGCATCCCCAGTTTCCCGCGGGCCTGGAGGTGACAGATGAGGTACTG
  GAGAAGGCAGCTGGGACCGATGTCAACAACATCTTCCAGCTCACTGTGGAGATGTTTGATTACATGGAT
  TGTGAGCTGAAGCTTTCTGAATCAGTTTTCCGACAGCTCAACACGGCCATCGCCGTATCCCAGATGTCC
  TCAGGCCAGTGCCGCCTGGCCCCCCTCATCCAGGTCATCCAGGACTGCAGCCACCTCTACCACTACACG
  GTCAAGCTCCTGTTCAAGCTACACTCTTGTCTCCCTGCGGACACCCTGCAAGGCCACAGGGACCGGTTC
  CACGAGCAGTTTCACAGCCTCAGGAACTTCTTCCGCAGAGCCTCCGACATGCTGTACTTCAAGCGGCTC
  ATCCAGATCCCCCGGCTGCCCGAGGGACCCCCTAACTTCCTGCGGGCCTCAGCCCTGGCTGAGCACATC
  AAGCCGGTGGTGGTGATCCCCGAGGAGGCCCCGGAAGATGAGGAGCCGGAGAATCTCATTGAGATCAGC
  ACAGGGCCCCCCGCGGGGGAGCCAGTGGTGGTGGCTGACCTCTTCGATCAGACGTTTGGACCCCCCAAT
  GGGTCTGTGAAGGACGACAGGGACCTCCAGATTGAGAGCTTGAAGAGAGAGGTGGAAATGCTCCGCTCT
  GAACTGGAGAAGATCAAGCTGGAGGCCCAGCGGTACATCGCGCAGCTGAAGAGCCAGGTGAATGCACTG
  GAGGGTGAGCTGGAGGAGCAGCGGAAGCAGAAGCAGAAGGCCCTGGTGGATAATGAGCAGCTCCGCCAC
  GAGCTGGCCCAGCTGAGGGCTGCCCAGCTGGAGGGCGAGCGGAGCCAGGGCCTGCGTGAGGAGGCTGAG
  AGGAAGGCCAGTGCCACGGAGGCGCGCTACAACAAGCTGAAGGAAAAGCACAGTGAGCTCGTCCATGTG
  CACGCGGAGCTGCTCAGAAAGAACGCGGACACAGCCAAGCAGCTGACGGTGACGCAGCAAAGCCAGGAG
  GAGGTGGCGCGGGTGAAGGAGCAGCTGGCCTTCCAGGTGGAGCAGGTGAAGCGGGAGTCGGAGTTGAAG
  CTAGAGGAGAAGAGCGACCAGCTGGAGAAGCTCAAGAGGGAGCTGGAGGCCAAGGCCGGAGAGCTGGCC
  CGCGCGCAGGAGGCCCTGAGCCACACAGAGCAGAGCAAGTCGGAGCTGAGCTCACGGCTGGACACGCTG
  AGTGCGGAGAAGGATGCTCTGAGTGGAGCTGTGCGGCAGCGGGAGGCAGACCTGCTGGCGGCGCAGAGC
  CTGGTGCGCGAGACAGAGGCGGCGCTGAGCCGGGAGCAGCAGCGCAGCTCCCAGGAGCAGGGCGAGTTG
  CAGGGCCGGCTGGCAGAGAGGGTATGGCCTCCCCAGATGCAGCAGCACCAC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG239106
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MNSIKNVPARVLSRRPGHSLEAEREQFDKTQAISISKAINTQEAPVKEKHARRIILGTHHEKGAFTFWS
  YAIGLPLPSSSILSWKFCHVLHKVLRDGHPNVLHDCQRYRSNIREIGDLWGHLHDRYGQLVNVYTKLLL
  TKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNNIFQLTVEMFDYMDCELKLSESVFRQLNTAIAVSQMS
  SGQCRLAPLIQVIQDCSHLYHYTVKLLFKLHSCLPADTLQGHRDRFHEQFHSLRNFFRRASDMLYFKRL
  IQIPRLPEGPPNFLRASALAEHIKPVVVIPEEAPEDEEPENLIEISTGPPAGEPVVVADLFDQTFGPPN
  GSVKDDRDLQIESLKREVEMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDNEQLRH
  ELAQLRAAQLEGERSQGLREEAERKASATEARYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQSQE
  EVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAGELARAQEALSHTEQSKSELSSRLDTL
  SAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGELQGRLAERVWPPQMQQHH
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001303097
• ORF Size: 1845 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).

Reference Data

• RefSeq: NM_001303097.2
• RefSeq Size: 2613 bp
• RefSeq ORF: 1848 bp
• Locus ID: 9026
• UniProt ID: O75146
• Cytogenetics: 12q24.31
• MW: 70.7 kDa
• Gene Summary: Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.[UniProtKB/Swiss-Prot Function]