Slap (SLA) (NM_006748) Human Tagged ORF Clone
CAT#: RG223060
- TrueORF®
SLA (tGFP-tagged) - Human Src-like-adaptor (SLA), transcript variant 3
ORF Plasmid: DDK
Lentiviral Particles: DDK w/ Puro mGFP w/ Puro
"NM_006748" in other vectors (5)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Symbol | Slap |
Synonyms | SLA1; SLAP |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG223060 representing NM_006748
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGAAACAGCATGAAATCCACCCCTGCGCCTGCCGAGAGGCCCCTGCCCAACCCGGAGGGACTGGATA GCGACTTCCTTGCCGTGCTAAGTGACTACCCGTCTCCTGACATCAGCCCCCCGATATTCCGCCGAGGGGA GAAACTGCGTGTGATTTCTGATGAAGGGGGCTGGTGGAAAGCTATTTCTCTTAGCACTGGTCGAGAGAGT TACATCCCTGGAATATGTGTGGCCAGAGTTTACCATGGCTGGCTGTTTGAGGGCCTGGGCAGAGACAAGG CCGAGGAGCTGCTGCAGCTGCCAGACACAAAGGTCGGCTCCTTTATGATCAGAGAGAGTGAGACCAAGAA AGGGTTTTACTCACTGTCGGTGAGACACAGGCAGGTAAAGCATTACCGCATTTTCCGTCTGCCCAACAAC TGGTACTACATTTCCCCGAGGCTCACCTTCCAGTGCCTGGAGGACCTGGTGAACCACTATTCTGAGGTGG CTGATGGCCTGTGCTGTGTGCTCACCACGCCCTGCCTGACACAAAGCACGGCTGCCCCAGCAGTGAGGGC CTCCAGCTCACCTGTCACCTTGCGTCAGAAGACTGTGGACTGGAGGAGAGTGTCCAGACTGCAGGAGGAC CCCGAGGGAACAGAGAACCCGCTTGGGGTAGACGAGTCCCTTTTCAGCTATGGCCTTCGAGAGAGCATTG CCTCTTACCTGTCCCTGACCAGTGAGGACAACACCTCCTTTGATCGAAAGAAGAAAAGCATCTCCCTGAT GTATGGTGGCAGCAAGAGAAAGAGCTCATTCTTCTCATCACCACCTTACTTTGAGGAC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG223060 representing NM_006748
Red=Cloning site Green=Tags(s) MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRES YIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQVKHYRIFRLPNN WYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQED PEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED TRTRPLE - GFP Tag - V |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_006748 |
ORF Size | 2869 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_006748.1, NP_006739.1 |
RefSeq Size | 2665 bp |
RefSeq ORF | 951 bp |
Locus ID | 6503 |
UniProt ID | Q13239 |
Cytogenetics | 8q24.22 |
Domains | SH2, SH3 |
Protein Families | Druggable Genome |
Gene Summary | Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC223060 | SLA (Myc-DDK-tagged)-Human Src-like-adaptor (SLA), transcript variant 3 |
USD 330.00 |
|
RC223060L3 | Lenti-ORF clone of SLA (Myc-DDK-tagged)-Human Src-like-adaptor (SLA), transcript variant 3 |
USD 630.00 |
|
RC223060L4 | Lenti-ORF clone of SLA (mGFP-tagged)-Human Src-like-adaptor (SLA), transcript variant 3 |
USD 630.00 |
|
SC115905 | SLA (untagged)-Human Src-like-adaptor (SLA), transcript variant 3 |
USD 300.00 |
|
SC327788 | SLA (untagged)-Human Src-like-adaptor (SLA) transcript variant 3 |
USD 330.00 |
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