EGFR (NM_201283) Human Tagged ORF Clone

CAT#: RC214877L1

Lenti ORF clone of Human epidermal growth factor receptor (EGFR), transcript variant 3 , Myc-DDK-tagged

Specifications

Product Data

• Product Name: EGFR (NM_201283) Human Tagged ORF Clone
• Symbol: EGFR
• Synonyms: ERBB; ERBB1; HER1; mENA; NISBD2; PIG61
• Vector: pLenti-C-Myc-DDK
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214877).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• Tag: Myc-DDK
• ACCN: NM_201283
• ORF Size: 1215 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_201283.1, NP_958440
• RefSeq Size: 1595
• RefSeq ORF: 1218
• Locus ID: 1956
• Cytogenetics: 7p11.2
• Protein Families: Stem cell relevant signaling - JAK/STAT signaling pathway, Protein Kinase, Secreted Protein, ES Cell Differentiation/IPS, Transmembrane, Adult stem cells, Cancer stem cells, Druggable Genome
• Protein Pathways: MAPK signaling pathway, ErbB signaling pathway, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Dorso-ventral axis formation, Focal adhesion, Adherens junction, Gap junction, Regulation of actin cytoskeleton, GnRH signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Pathways in cancer, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer
• MW: 42.4 kDa
• Gene Summary: Isoform 2 may act as an antagonist of EGF action. [UniProtKB/Swiss-Prot Function]