Cux1 (NM_001291239) Mouse Untagged Clone

CAT#: MC228879

Cux1 (untagged) - Mouse cut-like homeobox 1 (Cux1), transcript variant 6


  "NM_001291239" in other vectors (1)

Reconstitution Protocol

USD 767.00

3 Weeks*

Size
    • 10 ug

Product Images

Frequently bought together (4)
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Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Cux1
Synonyms CDP; Cutl1; Cux; Cux-1
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC228879 representing NM_001291239
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGAGCGCGCGTCAGGTCCGCTCCGAGCTGCCTTCTCCAGCCCGGTTCTCGAAAGCAAAGCCCCGGGGG
CCCCGCTGGACTGTAAGGAGACTGATTGTGGTTCCTCGTCGCCTCGAGGGGATGGTATCGGGGCTTCCCA
ATCCGCGGCGGAGCTGCCTGCGTGCCCAGAGGATGCTATTCTGCCTGCCACCCCTCATCGGAACCAGCTG
CTCGCCCTCGGGGTCCTCCCTGCTAGTGCTAGCTCCGCGTTCGCGGCGCCTGGACAGCCCCAGGATTCTG
CCAGGTGGATGTTGTGCGTAGCCGGAGCCAAGTTGAAGAGAGAACTTGATGCCACCGCAACAGTATTGGC
AAACAGGCAAGATGAGAGCGAACAGTCCAGAAAGCGGCTCATTGAGCAGAGCCGAGAATTCAAGAAGAAC
ACTCCAGAGGATTTACGCAAGCAGGTAGCACCACTGCTAAAGAGCTTCCAAGGGGAGATTGATGCACTGA
GTAAAAGAAGCAAAGAAGCAGAGGCAGCCTTCTTGACTGTGTACAAGAGACTAATTGATGTTCCAGATCC
GGTACCAGCCCTGGACGTCGGGCAACAGCTGGAAATAAAAGTGCAGCGTCTACACGACATTGAAACAGAG
AACCAGAAACTTAGGGAAACACTAGAAGAGTACAACAAGGAGTTTGCTGAAGTGAAAAATCAAGAGGTTA
CGATAAAAGCACTTAAGGAGAAAATCCGAGAATACGAGCAGACCCTGAAGAGTCAGGCCGAGACCATTGC
TCTGGAGAAAGAGCAGAAGCTACAAAATGATTTTGCAGAGAAGGAGAGAAAGCTGCAAGAGACACAGATG
TCCACCACCTCAAAACTGGAGGAAGCTGAGCACAAACTCCAGACTCTGCAAACAGCCCTGGAAAAAACTC
GAACAGAATTATTTGACCTGAAAACCAAATATGATGAAGAAACTACTGCAAAGGCCGATGAGATCGAGAT
GATCATGACCGACCTTGAACGAGCCAACCAGAGGGCAGAGGTGGCACAGAGAGAAGCAGAGACTTTAAGG
GAACAGCTCTCATCGGCCAACCACTCTCTCCAACTGGCCTCGCAGATCCAGAAGGCTCCAGATGTGGCCA
TAGAGGTGCTGACCCGATCCAGCCTAGAAGTAGAGTTGGCTGCCAAAGAGCGGGAGATCGCCCAGCTGGT
GGAAGATGTGCAGCGACTCCAGGCCAGCCTCACCAAGCTACGTGAGAATTCCGCCAGCCAGATCTCACAG
CTGGAGCAGCAACTGAATGCCAAGAATAGCACACTCAAACAACTGGAAGAAAAACTCAAAGGCCAGGCTG
ACTATGAAGAAGTGAAGAAAGAGCTGAACACCCTGAAGTCCATGGAGTTTGCACCATCGGAGGGAGCAGG
GACACAGGACTCTACCAAGCCCCTGGAGGTTTTACTCCTGGAGAAGAACCGCTCGCTGCAGTCCGAGAAT
GCCACGCTGCGCATCTCCAACAGTGACCTGAGCGGGCGCTGTGCGGAGCTGCAGATCCACCTCACTGAGG
CCACAGCCAAGGCTGTTGAGCAGAAGGAGCTGATCGCTCGCTTGGAGCAGGACCTCAGCACCATCCAGTC
CATCCAACGGCCTGATGCCGAGGGAGCTTCCGAGCAAGGCCTAGAGAAGATTCCAGAACCCATCAAGGAA
GCTACAGCTCTGTTCTATGGACCCTCAATGTCATCCAGTGGGACCCTTCCAGAAGGCCAGGTGGACTCCC
TGCTTTCCATCATCTCCAGCCAAAGGGAACGTTTCCGCACCCGGAACCAAGAGCTGGAAGCCGAGAGCCG
CATGGCCCAGCACACCATCCAGGCCCTGCAGAGCGAGCTGGACAGCCTGCGCGCTGACAACATCAAACTC
TTTGAGAAGATCAAGTTCCTGCAGAGTTACCCTGGCAGAGGTATCGGCAGTGACGACACGGAGCTGCGAT
ACTCCTCCCAATACGAGGAACGCCTGGACCCTTTCTCCTCCTTCAGCAAGAGGGAGCGGCAGAGGAAGTA
CCTGGGCCTGAGCCCCTGGGACAAGGCCACACTTGGCATGGGCCGTCTGATTCTCTCCAACAAGATGGCC
CGCACCATCAGCTTCTTTTACACCTTGTTCCTGCACTGCCTGGTCTTTCTGGTGCTGTACAAGCTGGCAT
GGAGTGAGAGTGTGGAGAGAGACTGTGCTGCCACCTGCGCCAAGAAGTTCGCCGATCATCTGCACAAATT
CCACGAGAGTGACAACGGAGCAGCAGCTGGTGACTTATGGCAGTGA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_001291239
Insert Size 2286 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001291239.1, NP_001278168.1
RefSeq Size 3363 bp
RefSeq ORF 2286 bp
Locus ID 13047
Cytogenetics 5 75.96 cM
Gene Summary Transcription factor involved in the control of neuronal differentiation in the brain. Regulates dendrite development and branching, and dendritic spine formation in cortical layers II-III (PubMed:20510857). Also involved in the control of synaptogenesis (Probable). In addition, it has probably a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator.[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (6) uses an alternate in-frame splice site in the central coding region, and contains alternate 3' exon structure and thus differs in the 3' coding region and 3' UTR, compared to variant 3. The encoded isoform (f) has a distinct C-terminus and is shorter than isoform c.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.