Abcb11 (NM_021022) Mouse Untagged Clone

CAT#: MC224235

Abcb11 (untagged) - Mouse ATP-binding cassette, sub-family B (MDR/TAP), member 11 (Abcb11), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Abcb11
• Synonyms: ABC1; ABC16; Bs; Bsep; Lit; Lith1; PFI; PFIC2; PGY; PGY4; SPGP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224235 representing NM_021022
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCTGACTCAGTGATTCTTCGCAGTGTGAAGAAATTTGGAGAGGAGAATCATGCTTTCGAATCAGATG
  GTTTCCATAACAATGATAAGAAATCAAGGTTACAAGATAAGAAGAAAGGGGAAGGCGCTCGAGTTGGCTT
  CTTTGAACTGTTTCGATTTTCTTCATCAAAAGACAACTGGCTGATGTTTATGGGAAGTGTGTGCGCATTG
  CTCCATGGAATGGCCCAGCCAGGCATGATTATTGTGTTTGGTATACTGACAGATATTTTTGTTGAATATG
  ACATTGAAAGACAAGAACTCAGTATTCCAGAAAAAGTGTGTATGAATAACACCATTGTATGGATCAACAG
  CTCCTTCAACCAGAACATGACAAACGGAACAAGCTGTGGGTTGGTGGACATTAACAGCGAAGTCATCAAA
  TTTTCTGGCATCTACGCAGGAGTTGGTGTGGCTGTCCTTATCCTAGGATACTTTCAAATAAGGTTGTGGG
  TAATCACTGGGGCTCGTCAGATAAGGAAAATGAGGAAATTTTACTTTCGGAGAATAATGAGAATGGAAAT
  CGGATGGTTTGACTGCACTTCTGTGGGAGAGCTCAATTCAAGATTCTCTGATGATATTAATAAAATTGAT
  GAAGCCATTGCCGACCAGATGGCCCTTTTCCTTCAGCGCCTGTCGACAGCTTTGTCTGGGCTCCTTTTAG
  GGTTCTACAGGGGTTGGAAATTAACCTTGGTGATTCTCGCTGTCAGTCCTCTCATTGGGATTGGGGCAGC
  CGTCATAGGTCTGAGTGTGGCCAAGTTCACGGAGCTTGAGTTGAAGGCTTATGCTAAAGCTGGGTCTATT
  GCCGATGAAGTCCTCTCATCTATTCGAACAGTGGCTGCTTTTGGTGGTGAGAATAAGGAGGTGGAAAGGT
  ATGAGAAAAATCTTATGTTTGCTCAGCGCTGGGGAATTTGGAAAGGAATGGTGATGGGCTTCTTCACTGG
  GTACATGTGGTGTCTCATTTTCTTCTGTTATGCACTGGCCTTCTGGTACGGCTCCAGACTTGTCCTGGAT
  GAAGGCGAGTACACACCAGGGACACTGATCCAGATTTTCCTCTGTGTCATAATAGCAGCTATGAATATTG
  GCAATGCATCTTCTTGTTTGGAAATCTTCTCCACTGGGTGTTCAGCAGCTTCCAGTATTTTCCAAACAAT
  AGACAGGCAACCCGTCATGGACTGCATGTCAGGAGATGGTTACAAGCTAGATCGAATCAAGGGCGAAATT
  GAGTTCCACAATGTGACCTTCCATTATCCTTCTCGACCAGAGGTGAAGATTTTAAATAACCTCAGCATGG
  TCATTAAGCCAGGGGAAACGACGGCGTTCGTGGGATCCAGTGGGGCAGGGAAGAGCACAGCACTACAGCT
  CATTCAGAGATTCTATGACCCCTGCGAAGGCATGGTGACTCTGGATGGCCATGACATTCGTTCTCTTAAC
  ATCCGGTGGCTGAGAGATCAAATTGGGATCGTGGAACAGGAGCCAGTTCTGTTCTCCACCACTATCGCAG
  AAAACATCCGCCTTGGTAGAGAAGAGGCGACAATGGAAGACATAGTCCAAGCTGCCAAGGATGCTAATGC
  ATACAACTTCATTATGGCCCTGCCACAGCAATTTGACACCCTAGTTGGAGAAGGAGGAGGCCAGATGAGT
  GGTGGGCAGAAGCAAAGGGTAGCCATCGCCCGCGCCCTCATACGGAAACCCAAGATCCTGCTTCTGGACA
  TGGCTACCTCAGCACTGGACAATGAGAGTGAGGCCAAAGTACAGGGAGCACTGAATAAGATCCAACATGG
  ACACACAATCATCTCAGTTGCCCATCGCCTATCAACAGTCAGATCTGCAGATGTGATCATTGGCTTTGAG
  CATGGAACAGCTGTGGAAAGAGGCACCCATGAAGAACTGTTAGAAAGAAAAGGTGTCTACTTCATGCTTG
  TGACCCTGCAAAGCCAAGAAGATAATACTCACAAAGAAACAGGCATAAAGGGAAAAGATACAACCGAAGG
  GGACACACCTGAGAGGACCTTTTCCAGAGGCAGCTATCAGGACAGTTTAAGAGCTTCCATCCGTCAACGA
  TCTAAGTCTCAGCTGTCTCATCTGTCACATGAACCTCCACTGGCTATAGGTGATCACAAGTCCTCTTACG
  AAGACAGAAAGGACAATGATGTGCTTGTGGAAGAAGTTGAACCTGCCCCAGTTAGGAGGATTCTAAAATA
  CAACATCTCAGAATGGCCCTACATACTGGTAGGGGCTTTGTGTGCAGCCATTAATGGGGCAGTCACACCC
  ATCTACTCCCTTTTATTCAGCCAGATCCTTAAGACTTTTTCACTCGTTGATAAAGAACAACAAAGGTCAG
  AGATTTACAGCATGTGCCTGTTTTTTGTCATCCTGGGCTGTGTATCACTTTTCACACAATTTCTGCAGGG
  TTACAATTTTGCCAAATCTGGAGAGCTCCTCACAAAAAGGCTGCGTAAATTTGGTTTCAAGGCAATGTTA
  AGACAAGATATTGGCTGGTTCGATGACCTCAAAAATAATCCTGGAGTACTAACAACTAGGCTTGCTACAG
  ATGCTTCCCAAGTTCAAGGGGCTACTGGCTCTCAAGTTGGGATGATGGTCAATTCCTTCACTAACATCTT
  TGTGGCCGTGCTCATCGCCTTCCTCTTTAACTGGAAGCTCAGTCTGGTTATATCAGTCTTCTTCCCCTTT
  TTGGCTTTATCGGGAGCTGTACAGACAAAAATGCTGACAGGATTCGCTTCTCAAGACAAGGAAATTCTGG
  AGAAGGCTGGCCAGATCACCAACGAAGCCCTTAGCAATATCCGCACCGTGGCTGGAATTGGAGTGGAGGG
  AAGATTTATTAAAGCATTTGAGGTTGAGCTGGAGAAGTCATACAAGACTGCCATTAGAAAGGCAAATGTC
  TATGGCCTCTGCTATGCCTTTTCCCAGGGGATATCATTTCTTGCCAATTCTGCAGCCTATAGATATGGAG
  GTTACTTAATAGTCTACGAAGATCTGAACTTCAGCTATGTTTTCAGGGTGGTCTCTTCCATTGCAATGAG
  CGCAACGGCTGTTGGAAGAACATTCTCTTACACACCGAGCTATGCCAAAGCTAAAATATCAGCTGCACGC
  TTTTTTCAACTGCTAGACAGAAAACCTCCAATTGATGTGTACAGTGGAGCAGGTGAAAAATGGGACAACT
  TCCAAGGGAAGATTGATTTTATCGACTGTAAATTTACATATCCTTCTCGACCTGATATACAAGTTCTGAA
  TGGACTGTCGGTATCTGTGGATCCTGGGCAGACGCTGGCATTCGTTGGGAGCAGTGGGTGTGGTAAAAGC
  ACCAGCATCCAGCTGTTGGAACGGTTCTACGATCCCGATCAGGGAACGGTGATGATAGATGGTCACGACA
  GCAAAAAAGTCAATGTTCAGTTCCTCCGTTCAAACATTGGGATTGTCTCCCAGGAGCCCGTGTTATTTGA
  CTGTAGCATAATGGACAACATCAAGTATGGGGACAACACCAAAGAGATCTCCGTGGAGAGAGCTATAGCT
  GCCGCAAAGCAGGCTCAGCTGCATGACTTCGTCATGTCACTCCCAGAGAAATATGAAACTAATGTTGGGA
  TCCAGGGCTCTCAACTCTCTCGCGGGGAGAAACAACGCATTGCTATTGCTCGGGCCATTGTACGAGATCC
  TAAAATCTTGCTACTGGATGAAGCTACATCTGCCTTAGACACAGAAAGTGAAAAGACAGTGCAGCTTGCT
  CTGGACAAAGCCAGAGAGGGTCGGACCTGTATTGTCATTGCTCATCGCTTGTCTACTATCCAGAACTCAG
  ATATCATCGCCGTCATGTCACAAGGAGTGGTGATTGAAAAGGGGACCCATAAGAAACTGATGGACCAGAA
  GGGGGCCTACTACAAGCTGGTCATCACTGGAGCCCCCATCAGTTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_021022
• Insert Size: 3966 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_021022.3, NP_066302.2
• RefSeq Size: 4899 bp
• RefSeq ORF: 3966 bp
• Locus ID: 27413
• UniProt ID: Q9QY30
• Cytogenetics: 2 39.69 cM
• Gene Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt transporter in humans and mice. Mutations in the human gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]