Fnip2 (NM_001162999) Mouse Untagged Clone

CAT#: MC223606

Fnip2 (untagged) - Mouse folliculin interacting protein 2 (Fnip2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fnip2
• Synonyms: D630023B12Rik; mKIAA1450
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223606 representing NM_001162999
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCCCGACCCTGCTCCAGAAGCTCTTCAACAAAAGGGGCGGCGGCGCAGCGTCTGCCCAGGCCCGGC
  CGCCCAAGGAGGAGCCGGCCTTCAGTTGGTCGTGTTCGGAGTTTGGCTTGAGTGACATCCGCCTGCTAGT
  TTACCAGGACTGTGAGAGGAGAGGCAGACAAGTCATGTTTGACTCCAGAGCCGTTCAGAAGATGGAAGAG
  GCAGCAGCTCAGAAAGCAGAGGATGTTCCTATTAAAATGTCAGCCAGATGCTGTCAGGAAAGCAGCAGCA
  GCAGCGGCAGCAGCAGCAGCGGCAGCAGCTCTTCTCATGGCTTTGGAGGATCTTTACAACACGCTAAGCA
  ACAGCTTCCAAAGTACCAATACACGAGACCAGCATCTGATGTCAGCATGCTTGGGGAGATGATGTTTGGC
  TCAGTTGCAATGAGTTACAAAGGCTCCACCCTGAAGATACACTACATACGATCTCCTCCACAACTGATGA
  TTAGTAAAGTCTTTTCTGCTACAATGGGTAGCTTCTGTGGAAGTACAAATAATCTGCAGGACAGCTTCGA
  ATACATTAACCAAGATCCTCAGGCTGGAAAACTGAACACAAATCAGTACAATTTGGGTCCTTTTCGTACT
  GGAAGTAACCTAGCACACAGCACACCTGTTGATATGCCAAGCAGAGGGCAGAATGAAGACAGGGACAGCG
  GCATTGCTCGATCAGCTTCACTGAGCAGCCTTTTGATCACGCCCTTCCCGTCTCCAAGCTCTTCTACATC
  CTCTTCCAGCAGTTACCAGCGCCGCTGGCTCCGAAGTCAGACAACGAGTTTGGAAAATGGCATCTTTCCA
  AGGAGGTCAACTGATGAGACATTTAGCTTGGCCGAAGAAACGTGTAGCTCTAATCCAGCTATGGTTAGAA
  GGAAGAAGATCGCCATCAGCATCATCTTTTCCCTGTGTGAGAGAGAGGCCGCCCAGCGGGATTTCCAGGA
  CTTCTTTTTCTCCCACTTCCCCCTGTTTGAATCTCACATGAACAGGCTGAAGGGTGCAATCGAAAAGGCC
  ATGATCTCCTGTAGGAAGATCTCTGAATCAAGTCTCCGAGTCCAGTTCTATGTGAGCCGTCTGATGGAAG
  CACTGGGAGAATTCAGAGGGACTATCTGGAACTTATATTCTGTTCCAAGGATAGCTGAACCAGTTTGGCT
  TACCATGATGTCAAACACCTTGGAGAAAAACCAACTCTGCCAGCGCTTTCTCAAGGAATTTATACTTCTG
  ATTGAACAAGTCAACAAAAACCAGTTTTTTGCTGCCTTACTGACTGCGGTGTTAACCTACCACCTGGCCT
  GGGTACCAACTGTCATGCCTGTTGACCACCCTCCCATTAAAGCCTTCTCGGAGAAGCGTACCTCTCAGTC
  AGTGAACATGCTGGCCAAAACACATCCATATAATCCTCTCTGGGCGCAGCTGGGTGACCTCTATGGAGCT
  ATAGGCTCTCCGGTGAGACTGACTCGCACTGTGGTGATTGGGAAGCAGAAGGATTTGGTCCAGCGCATTC
  TTTATGTTCTGACCTACTTTCTCCGTTGCTCTGAACTGCAAGAGAATCAGCTGAGCTGGAGTGGAAATCC
  CAGTGAGGATGACCAGGTTATAAATGGGAGCAAGATAATAACCGCCCTGGAAAAGGGAGAGGTGGAAGAG
  TCTGAGTATGTGGTAGTTACCGTGAGCAGTGAGCCTGCCCTGGTACCACCAATCCTACCACAGGGGACAG
  CTGAGAGGAGGAGCCCTGAGCCTACAGTAGTAGCTGAGATCTCGGAAGGCGTTAATACTAGCGAACTGGG
  TCACAAACCTGAAAAGAACAGATGCAAGAGGCCAGAGCAGAATTCCGAGGCCAGTAGTATGGGCTTCCAA
  GAGGCAGAACCTGACAGTTCGTGGATACCTCAAGGCATATTCTGTGAGGACAAACAGAATGACCAAGAGG
  CAACCCAGGATTGTTCTTCAAGTCCTCCCAGCTGTGAGGTGCCCAGGGTAAGAAGGAGGATGGACCAACA
  AACCCTCCACTCGAAGCTGCATGGGGAGACGCTAAAGAAGCGAGCAGAGCAGTCCGCAGCCTGGCCCTGC
  CCAGACAGGCATTCCCAGGAGGATCCTCCTGTCGAAAAGGTCACTTTCCACATTGGGAGTTCCATCTCCC
  CGGAGTCTGACTTTGAAAGCCGGACCAAAAGAATGGAGGAGCGATTAAAGGCCTGTGGACATTTCCATGG
  GGCTAGTGCCTCTGCCAGCTCTAGCATGGACACTGGGCTGACTCAAGAGCAGCAGGGCTCTGGGTGCTCC
  TTCAAAGCTGACTTTGAAAAGGACATCACGCCTCAGGACCACTCTTCAGGGGGGGAAGGTGTCTCTGAGG
  ACAGAGGCCTCCGGGCCAACATGACACATGCTGTGGGACAACTTAGCCAAGTTGATGGCCCCCTTGCACA
  TTCCCTTTGTGCCGCAGAAAGTGGGCGGAGACTGCTGGAACAGACTAGAGATGTGCAATTAAAAGGCTAC
  AAAGGACCTTCATCGGAGCCTGTTCCAAACAGATGTAGACAGCAGGGTGGCCTGCTGATTGCTGCAGATG
  TCCCCTATGGGGATGCCAGTGGTAAGGGCAACTACAGGAGCGAAGGAGACATTCCCAGGAACGAGAGCTT
  GGATAGTGCTCTTGGAGACAGTGATGATGAAGCGTGTGTCTTAGCCCTGCTAGAACTAGGTCACAGTTGT
  GACAGGACTGAAGAGTCCTTGGAAGTGGAGCTGCCTCTGCCAAGGTCTCAGAGCACCAGCAAGGCAAATG
  TTAGAAATTTTGGCCGCTCACTTCTGGCAGGTTACTGTGCCACGTACATGCCTGATCTGGTGCTGCATGG
  AACCAGCAGCGATGAGAAGCTGAAGCAGTGCCTGGCAGCTGATCTGGTCCACACGGTGCACCATCCAGTA
  CTCGATGAGCCCATAGCCGAAGCTGTCTGTATCATTGCAGACACTGACAAGTGGACTGTCCAGGTGGCCA
  CGAGTCAGCGGAAGGTGACGGACACCATGAAGCTGGGCCAGGATGTCTTGGTCTCCAGTCAGGTGTCCAG
  TTTACTTCAGTCCATCTTACAGCTCTATAAGCTTCACCTCCCTGCTGATTTTTGTATCATGCATCTGGAA
  GACAGACTGCAGGAGATGTACCTGAAGAGTAAAATGCTTTCAGAGTATCTCCGGGGACACACGCGTGTGC
  ACGTGAAAGAGCTGAGTGTGGTGCTGGGGATCGAATCCAATGACCTGCCTCTGCTGACGGCCATCGCCAG
  CACTCACTCTCCGTACGTGGCACAGATCCTCTTATAG
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001162999
• Insert Size: 3327 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001162999.2, NP_001156471.1
• RefSeq Size: 7095 bp
• RefSeq ORF: 3327 bp
• Locus ID: 329679
• UniProt ID: Q80TD3
• Cytogenetics: 3 E3
• Gene Summary: Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1 (By similarity). May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (PubMed:19137017).[UniProtKB/Swiss-Prot Function]