Sgsm2 (NM_197943) Mouse Untagged Clone

CAT#: MC223168

Sgsm2 (untagged) - Mouse small G protein signaling modulator 2 (Sgsm2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Sgsm2
• Synonyms: D630003G22Rik; mKIAA0397; R74628; Rutbc1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223168 representing NM_197943
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCAGCGCAGAGGACGCGGTCAAAGAAAAGCTGCTGTGGAACGTGAAGAAGGAGGTGAAACAAATCA
  TGGAGGAGGCTGTCACCAGGAAATTCGTGCATGAAGATAGCAGCCACATCATTGCTCTGTGTGGTGCTGT
  GGAGGCTTGCCTCCTGCATCAGCTAAGACGCCGTGCTGCTGGCTTTCTGCGAAGTGACAAGATGGCGGCC
  CTGTTCACCAAAGTGGGGAAGACATGCCCCGTGGCTGAAGATATCTGCCACAAGGTGCAGGAGTTGCAGC
  AACAGGCAGAGGGCAGGAAACCCTCGGGAGGCAGCCAAGAAGCCCTTCGGAAACAGGGCTCTACCGGTGG
  GAAGGCCCCAGCTCTCAGCCCACAGGCCTTGAAACACATATGGGTACGCACAGCACTCATGGAGAAAGTT
  CTGGACAGGGTTGTACAGTACCTGGCCGAAAACTGCAGCAAGTATTACGAGAAGGAAGCATTATTGGCAG
  ATCCTGTGTTTGGCCCAATCCTGGCATGTCTCCTAGTGGGACCCTGTGCCTTGGAATACACGAAGCTCAA
  GACAGCTGATCACTACTGGACTGACCCCTCTGCTGATGAGCTGGTTCAGAGGCACCGTATCCGGGGTCCC
  CCTAACCGTCAGGACTCCCCGGCAAAGCGCCCTGCCCTGGGGATCCGGAAGCGCCACTCTAGTGGGAGTG
  CCTCAGAAGACCGGCTTGCCGCCTGCGCCCGTGAGTACGTGGAGTCTCTGCACCAGAACTCAAGAACACG
  CCTGCTCTATGGCAAGAACAACGTGTTGGTGCAGCCGAAGGAGGACATGGAGGCAGTCCCTGGCTACCTC
  TCCCTGCACCAGTCTGCAGAGAACCTAACCCTGAAGTGGACTCCCAACCAACTCATGAACGGGACTCTCG
  GGGACTCTGAGCTAGAGAAGAGTGTTTACTGGGACTATGCCTTGGTGGTGCCCTTCAGTCAGATCGTCTG
  CATCCACTGCCACCAGCAAAAGAGCGGTGGCACGCTTGTGCTGGTGAGCCAGGATGGCATCCAGAGGCCG
  CCACTACACTTCCCACAGGGAGGACACCTGCTGTCCTTCCTGTCATGTCTGGAGAATGGGCTGCTGCCTC
  GTGGACAGCTTGAGCCCCCGCTGTGGACCCAGCAGGGAAAGGGCAAGGTTTTCCCCAAGCTACGGAAACG
  CAGCAGCATTCGGTCCATTGATGTAGAGGAGCTGGGTGTCGGACGGGCAACGGACTACGTGTTCCGGATC
  ATCTACCCCGGACATAGGCACGAGCATAATGCTGGCGACATGATTGAGATGCAGGGTTTCGGACCCAGCC
  TAACAGCCTGGCACCTAGAGCCCCTGTGTAGCCAGGGCTCCTCCTGCCTTTCCTGTTCCTCCAGTAGCTC
  CCCATATGCAACCCCCAGTCACTGCAGCTGCATTCCTGACAGGTTGCCCCTCCGGCTGCTGTGTGAGAGC
  ATGAAGAGGCAGATTGTGTCCCGGGCCTTCTACGGCTGGCTAGCCTACTGTCGCCACCTGTCCACAGTGA
  GGACACACCTGTCTGCATTGGTGCATCACAACATCATTCCACCAGACAGGCCCCCGGGGGCCTCAGGTGG
  CCTCACCAAGGATGTGTGGAGCAAGTATCAGAAGGACGAAAAGAACTACAAGGAGCTGGAGCTGCTGCGG
  CAGGTGTACTATGGAGGCGTGGAACACGAGATTCGCAAGGACGTCTGGCCCTTCCTACTTGGCCACTACA
  AGTTTGGCATGAGCAAGAAGGAGATGGAGCAGGTGGATACAGCAGTGGCAGCAAGGTACCAGCAGGTGTT
  GGCAGAGTGGAAGGCCTGCGAGGTGGTGGTGAGGCAGCGGGAGCGGGAGGCTCACCCAGCCACGCTCACC
  AAGTTCTCCTCGGGCAGCAGCATCGATAGCCACGTGCAGCGCCTCGTGCACCGGGATTCCACCATCAGCA
  ATGATGTATTTATCTCTGTGGATGATCTTGAGCCCTCTGGACCTCAGGACCTGGAAGATTCCAAACCAAA
  GCGGGAACAGGAGCCAGGAGCTGGGACCCCGGGCATAGCAGCTGCAGAGCAGCAGTCTGTGGAGTTTGAC
  TCTCCAGACTCAGGGCTGCCTTCCTCCCGCAACTACTCTGTGGCCTCAGGCATCCAGTCCAGCCTAGATG
  AGGCACAGAGTGTGGGCTTTGAAGACGACGGTGCTGGAGAAGATGGCTCCGAGGGTCCAGCCACTGCAGC
  CCACACTTTCCCGGGACCCCACGATCCAGGCCAGGAGACGCTTGCACCTGCCAGTGAGCTTGAAGCAGGC
  CAGGAGCTCGCAGCTGTGTGCGCCGCAGCCTATACTATAGAATTACTGGACACCGTGGCCTTAAATCTGC
  ACCGCATAGACAAGGATGTGCAGAGATGTGACCGCAACTACTGGTACTTCACGACCTCCAACCTCGAGAG
  GCTCAGAGACATCATGTGCAGCTACGTGTGGGAGCACCTGGATATGGGCTACGTGCAGGGCATGTGTGAT
  CTCCTGGCACCTCTCCTGGTCATCCTTGACAATGACCAGCTGGCCTACAGCTGCTTCAGCCACCTCATGA
  AGAGGATGGGCCAGAACTTCCCCAGTGGGGGTGCCATGGACAGCCACTTTGCCAACATGCGCTCCCTCAT
  CCAGATCTTGGACTCAGAGCTATTTGAGCTGATGCATCAAAATGGAGACTATACCCACTTCTATTTCTGT
  TATCGCTGGTTCCTGCTGGATTTTAAAAGAGAGCTGCTGTATGAGGACGTGTTTGCAGTGTGGGAAGTGA
  TCTGGGCAGCCAGGCGCATCTCCTCAGAGCACTTTGTCCTGTTCATCGCCCTGGCCCTGGTGGAGGCCTA
  CAGAGAGATTATCCGTGACAACAACATGGACTTCACCGACATCATCAAATTCTTCAACGAGCGGGCTGAG
  CGGCATGATGCCCAGGAGATCCTGCGGATTGCCCGGGACTTGGTCCACAAGGTGCAGATGCTCATAGACA
  ACAAGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_197943
• Insert Size: 3018 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_197943.2, NP_922934.2
• RefSeq Size: 4791 bp
• RefSeq ORF: 3018 bp
• Locus ID: 97761
• UniProt ID: Q80U12
• Cytogenetics: 11 B5
• Gene Summary: Possesses GTPase activator activity towards RAB32, RAB33B and RAB38. Regulates the trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes by inactivating RAB32 and RAB38. Inhibits RAB32 and RAB38 activation both directly by promoting their GTPase activity and indirectly by disrupting the RAB9A-HPS4 interaction which is required for RAB32/38 activation (PubMed:26620560).[UniProtKB/Swiss-Prot Function]