Nrg3 (NM_001190188) Mouse Untagged Clone

CAT#: MC220573

Nrg3 (untagged) - Mouse neuregulin 3 (Nrg3), transcript variant 3, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Nrg3
• Synonyms: ska
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC220573 representing NM_001190188
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGTGAAGGGGCGGCCGGTGCCTCGCCACCTGGTGCCGCTTCGGCAGCCGCCGCCTCAGCCGAGGAGG
  GCACCGCGGCGGCTGCGGCGGCGGCGGCGGCGGGCGGGGGCCCGGACGGCGGCGGAGAAGGGGCGGCCGA
  ACCTCCCCGGGAGTTACGCTGTAGCGACTGCATCGTGTGGAACCGGCAGCAGACGTGGTTGTGCGTGGTG
  CCTCTGTTCATCGGCTTCATCGGCCTGGGGCTCAGCCTCATGCTGCTTAAATGGATCGTGGTAGGCTCCG
  TCAAGGAGTACGTGCCCACGGACCTGGTGGACTCCAAGGGAATGGGCCAGGACCCCTTCTTCCTCTCCAA
  GCCCAGCTCTTTCCCCAAGGCTATGGAAACCACCACAACAACCACTTCTACCACGTCCCCCGCCACCCCC
  TCTGCCGGCGGCGCCGCTTCTTCCAGGACGCCTAACCGGATTAGCACCCGCTTGACCACCATCACACGGG
  CACCCACCCGCTTCCCTGGGCACCGGGTTCCCATCCGGGCTAGCCCGCGCTCTACCACAGCACGGAACAC
  TGCTGCCCCTCCGACGGTCCTGTCCACCACGGCCCCTTTCTTCAGTAGCAGCACGCCCGGCTCCCGACCC
  CCGATGCCAGGAGCCCCCAGTACGCAGGCGATGCCTTCCTGGCCCACTGCGGCGTATGCTACCTCCTCCT
  ACCTCCACGATTCCACTCCCTCCTGGACCCTGTCACCCTTTCAGGATGCTGCTGCCGCCTCTTCCTCCTC
  ACCCTCTTCCACCTCCTCCACTACCACCACCCCAGAAACTAGCACCAGCCCCAAATTTCATACTACAACA
  TACTCCACTGAACGATCTGAGCACTTCAAACCCTGTCGAGACAAGGACCTGGCGTATTGTCTCAATGATG
  GTGAATGCTTTGTGATTGAGACCCTGACAGGATCCCATAAGCACTGTCGGTGCAAGGAAGGCTACCAAGG
  AGTCCGTTGTGATCAATTTCTGCCGAAAACAGACTCCATCTTATCGGATCCAACAGACCACTTGGGGATT
  GAATTCATGGAGAGTGAAGACGTTTATCAAAGGCAGGTGCTGTCAATTTCATGTATCATCTTTGGAATTG
  TCATCGTGGGCATGTTCTGTGCAGCATTCTACTTCAAAAGCAAGAAACAAGCTAAACAAATTCAGGAGCA
  CCTGAAAGAGTCACAGAATGGGAAGAACTACAGCCTCAAGGCATCCAGCACAAAGTCTGAGAGCTTGATG
  AAGAGCCATGTCCATCTACAAAATTATTCAAAGGCGGATAGGCATCCTGTGACTGCGCTGGAGAAAATAA
  TGGAGTCAAGTTTTTCAGCTCCCCAGTCGTTCCCAGAAGTCACTTCTCCTGACCGAGGAAGCCAGCCTAT
  CAAGCACCACAGCAGAAGTATTTCTTCTTGCTGCAGCCCAGGACAAAGGAGTGGGATGTTGCATAGGAAT
  ACTTTCAGAAGGGCACCACCCTCACCCCGAAGTCGACTGGGTGGTATTGTAGGACCAGCATATCAACAAC
  TTGAAGAATCAAGAATTCCAGACCAGGATACGATACCTTGCCAAGGGTATGTGTCCAATGGCTTAAGAAC
  CCAACAAAATGCATCAATAAATATGCAACTGCCTTCAAGAGAGACAAACCCCTATTTTAATAGCTTGGAT
  CAAAAGGACCTGGTGGGTTATTTATCCCCAAGGGCCAATTCTGTGCCCATCATCCCGTCGATGGGTCTAG
  AAGAAACCTGCATGCAAATGCCAGGGATTTCTGACGTCAAAAGCATTAAATGGTGCAAAAACTCCTACTC
  CGCTGACATTGTCAACGCGAGTATGCCAGTCAGTGATTGTCTTCTAGAAGAACAACAGGAAGTGAAAATA
  TTACTAGAGACTGTGCAGGAACAGATCCGGATTCTGACTGATGCCAGACGGTCAGAAGACTTCGAACTGG
  CCAGCATGGAAACTGAGGACAGTGCGAGCGAAAACACAGCCTTTCTCCCCCTGAGTCCCACGGCCAAATC
  AGAACGAGAGGCACAATTTGTCTTAAGAAATGAAATACAAAGAGACTCTGTGCTAACCAAGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001190188
• Insert Size: 2094 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001190188.1, NP_001177117.1
• RefSeq Size: 3964 bp
• RefSeq ORF: 2094 bp
• Locus ID: 18183
• Cytogenetics: 14 B
• Gene Summary: Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (3) uses an alternate in-frame splice site and lacks an in-frame exon in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1. Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.