Tgfbr1 (NM_009370) Mouse Untagged Clone

CAT#: MC216976

Tgfbr1 (untagged) - Mouse transforming growth factor, beta receptor I (Tgfbr1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Tgfbr1
• Synonyms: AL; Alk; Alk-5; ALK5; AU017191; ESK2; Tbet; Tbeta; TbetaR-I; TbetaRI; TGFR-1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC216976 representing NM_009370
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGGCGGCGGCCGCTGCTCCACGTCGTCCGCAGCTCCTCATCGTGTTGGTGGCGGCGGCGACGCTGC
  TCCCGGGGGCGAAGGCATTACAGTGTTTCTGCCACCTCTGTACAAAGGATAATTTTACCTGTGAGACAGA
  TGGTCTTTGCTTTGTCTCAGTCACTGAGACCACAGACAAAGTTATACACAATAGTATGTGTATAGCTGAA
  ATTGACCTAATTCCTCGAGACAGGCCATTTGTATGTGCACCATCTTCAAAAACAGGGGCAGTTACTACAA
  CATATTGCTGCAATCAGGACCACTGCAATAAAATAGAACTCCCAACTACAGGACCTTTTTCAGAAAAGCA
  GTCAGCTGGCCTTGGTCCTGTGGAGCTGGCAGCTGTCATTGCTGGTCCAGTCTGCTTCGTCTGCATTGCA
  CTTATGCTGATGGTCTATATCTGCCATAACCGCACTGTCATTCACCACCGTGTGCCAAATGAAGAGGATC
  CATCACTAGATCGCCCTTTCATTTCAGAGGGCACCACCTTAAAAGATTTAATTTATGATATGACAACATC
  AGGGTCTGGATCAGGTTTACCACTGCTTGTTCAAAGAACAATTGCCAGGACCATTGTGTTACAAGAAAGC
  ATTGGCAAAGGTCGGTTTGGAGAAGTTTGGCGAGGCAAATGGCGGGGAGAAGAAGTTGCTGTGAAGATAT
  TCTCTTCTAGAGAAGAGCGTTCATGGTTCCGAGAGGCAGAGATTTATCAGACTGTAATGTTACGCCATGA
  AAATATCCTGGGATTTATAGCAGCAGACAACAAAGACAATGGGACATGGACGCAGCTGTGGTTGGTGTCA
  GATTATCATGAGCATGGATCCCTTTTCGATTACTTGAATAGATACACTGTTACTGTGGAAGGAATGATCA
  AGCTTGCTCTGTCCACAGCAAGTGGTCTTGCCCATCTTCACATGGAGATTGTTGGTACCCAAGGAAAACC
  AGCTATTGCCCATAGAGATTTGAAATCAAAGAATATCTTGGTGAAGAAAAATGGAACCTGTTGTATTGCA
  GACTTGGGACTTGCTGTGAGACATGATTCTGCCACAGATACAATTGATATTGCTCCAAACCACAGAGTAG
  GCACTAAAAGGTACATGGCCCCTGAAGTTCTAGATGATTCCATAAATATGAAACATTTTGAATCCTTCAA
  ACGCGCTGACATCTATGCAATGGGCTTAGTGTTCTGGGAAATTGCTCGACGCTGTTCTATTGGTGGAATC
  CATGAAGACTATCAGTTGCCTTATTATGATCTTGTACCTTCTGATCCATCGGTTGAAGAAATGAGAAAAG
  TAGTTTGCGAACAGAAGTTAAGGCCAAATATTCCAAACAGATGGCAGAGCTGTGAGGCCTTGAGAGTGAT
  GGCTAAAATTATGAGAGAATGCTGGTATGCCAATGGAGCAGCAAGGCTGACAGCTTTGCGAATTAAAAAA
  ACATTGTCACAACTCAGCCAACAGGAAGGCATCAAAATGTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_009370
• Insert Size: 1512 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_009370.3, NP_033396.1
• RefSeq Size: 5735 bp
• RefSeq ORF: 1512 bp
• Locus ID: 21812
• UniProt ID: Q64729
• Cytogenetics: 4 26.02 cM
• Gene Summary: This gene encodes a member of the transforming growth factor beta (TGF-beta) receptor family of proteins. These proteins comprise one component of the TGF-beta signaling pathway, which transduces extracellular signals into gene expression changes to regulate a wide range of cellular responses, including proliferation, migration, differentiation and apoptosis. Homozygous knockout mice for this gene exhibit impaired angiogenesis and embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).