Foxl2 (NM_012020) Mouse Untagged Clone

CAT#: MC209752

Foxl2 (untagged) - Mouse forkhead box L2 (Foxl2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Foxl2
• Synonyms: AU045128; BPES; Pfrk; PINTO
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC209752 representing NM_012020
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATGGCCAGCTACCCCGAGCCCGAAGACACGGCGGGGACCCTGCTGGCTCCGGAGAGCGGACGCGCAG
  TCAAAGAGGCCGAGGCGTCGCCGCCGAGTCCCGGCAAGGGAGGCGGGACAACACCGGAGAAACCAGACCC
  CGCGCAGAAGCCCCCGTACTCGTACGTGGCGCTCATCGCCATGGCGATCCGCGAGAGCGCCGAGAAGAGG
  CTCACTCTGTCCGGCATCTACCAGTACATCATAGCCAAGTTCCCGTTCTACGAGAAGAACAAGAAGGGCT
  GGCAGAATAGCATCCGCCACAACCTCAGCCTCAACGAGTGCTTCATCAAGGTGCCGCGCGAGGGCGGCGG
  CGAGCGCAAGGGCAACTACTGGACGCTCGACCCGGCCTGCGAGGACATGTTCGAGAAGGGCAACTACCGG
  CGCCGCCGCCGCATGAAGCGGCCCTTCCGGCCGCCGCCCGCTCACTTCCAGCCCGGCAAGGGGCTCTTCG
  GGAGCGGAGGAGCGGCGGGTGGCTGCGGCGTGCCCGGAGCTGGGGCCGATGGCTATGGCTACCTGGCGCC
  ACCCAAGTACCTGCAATCGGGGTTCCTCAACAACTCCTGGCCCCTGCCGCAGCCTCCCTCGCCCATGCCC
  TACGCCTCCTGCCAGATGGCGGCGGCTGCGGCGGCCGCTGCTGCAGCCGCTGCAGCCGCCGGCCCGGGCA
  GCCCCGGTGCAGCCGCGGTGGTCAAGGGGCTGGCGGGCCCCGCCGCCTCCTACGGGCCGTACTCGCGCGT
  GCAGAGCATGGCGCTGCCTCCGGGCGTCGTGAACTCCTACAACGGCCTGGGGGGCCCTCCTGCCGCACCA
  CCGCCGCCGCCACCGCCGCCGCACCCTCACCCGCACCCTCACGCACATCATCTGCACGCGGCCGCTGCGC
  CCCCGCCAGCCCCGCCACACCACGGGGCTGCCGCGCCTCCCCCGGGTCAGCTCAGTCCCGCCAGCCCGGC
  CACCGCCGCGCCCCCGGCACCCGCGCCCACGAGCGCGCCCGGCCTGCAGTTCGCCTGCGCCCGGCAACCC
  GAGCTCGCCATGATGCATTGCTCATACTGGGACCACGACAGCAAGACGGGCGCGCTGCACTCGCGTCTGG
  ATCTCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_012020
• Insert Size: 1128 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012020.2, NP_036150.1
• RefSeq Size: 2520 bp
• RefSeq ORF: 1128 bp
• Locus ID: 26927
• UniProt ID: O88470
• Cytogenetics: 9 E3.3
• Gene Summary: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. Is a regulator of CYP19 expression. Is a transcriptional repressor of STAR. Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element.[UniProtKB/Swiss-Prot Function]