Rab3ip (NM_001003950) Mouse Untagged Clone

CAT#: MC207874

Rab3ip (untagged) - Mouse RAB3A interacting protein (Rab3ip), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Rab3ip
• Synonyms: B230311A06; Gtpat12; Rabin3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC207874 representing NM_001003950
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTAACGACCCCTTGGAAGGCTTCCATGAAGTGAACCTTGCTTCGCCTACTTCTCCAGACCTTCTTG
  GTGTGTGTGACCCGGGAACCCAAGAGCAGACTACCTCCCCGAGCGTCATCTACCGGCCACACCCCTCCAC
  GTTATGCGCTGCCCCTCTCCAGGCCAATGCCTTAGATCTTTCTGATCTTCCTACACAACCTGTGTATTCG
  TCCCCCAGGCATTTCAACTGTGCAGAAGTATCTAATATCAGCGCTCATGCTCCGGATCCAGCATCATCGG
  TACCCTCTGCGGTAGCATCAGGGCTCACGAAGTTAACCTCCAGGAAGGACAGCTGTAATGCAGAGAGGGA
  GTTTCTGCAGGGCGCCACCATCACCGAGGCTTCTGCTGGCAATGATGACATCTTTGGGTTGAGCACGGAT
  AGCCTGTCGCGTTTACGAAGCCCATCTGTTCTGGAAGTTAGAGAGAAGGGCTACGAAAGGTTAAAGGAAG
  AACTTGCAAAAGCTCAGAGGGAAGCTCACAAGATGGTGAGGGAAGCGAACGTCAAGCAAGCCACTGCAGA
  GAAGCAGCTGAAGGAAGCCCAGGGGAAAATTGATGTACTTCAGGCTGAAGTGGCCGCTCTGAAGACACTC
  GTACTGTCCAGTTCTCCAACATCGCCTACGCAGGAGCCTCTGGCGGCTGCAAAGACCCCCTTTAAAAGGG
  GGCACACAAGGAACAAAAGTACAAGCAGCGCCATGGGTGGGAGCCACCAGGACTTGAGTGTGATCCAGCC
  AATCGTAAAAGACTGCAAAGAGGCTGATTTATCGCTGTATAATGAGTTCAGATCTTGGAAGGATGAGCCC
  ACGATGGACAGAACGTGTCCTTTCCTGGACAAAATCTACCAGGAGGACATCTTTCCATGTTTAACATTTG
  CAAAGAGTGAGTTGGCTTCAGCTGTTCTGGAGGCTGTGGAGAACAACACTCTAAGCATCGAACCAGTGGG
  GTTGCAGCCCATCCGCTTCGTGAAGGCTTCCGCTGTCGAGTGCGGAGGGCCAAAAAAGTGTGCGCTCACT
  GGCCAGAGTAAGCCCTGCAGGCACAGGATTAGGCTCGGGGACTCCAGCTGCTGTTACTACATCTCTCCTT
  TCTGCAGATACAGGATCACTTCTGTATGTAACTTTTTTACATACATTCGATACATTCAGCAGGGACTCGT
  GAAACAGCAGGATGTCGATCAGATGTTTTGGGAAGTTATGCAGTTGAGAAAGGAGATGTCGTTGGCAAAG
  CTGGGATATTTCAAAGAGGAACTCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001003950
• Insert Size: 1287 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001003950.2, NP_001003950.1
• RefSeq Size: 2690 bp
• RefSeq ORF: 1287 bp
• Locus ID: 216363
• UniProt ID: Q68EF0
• Cytogenetics: 10 64.96 cM
• Gene Summary: Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity).[UniProtKB/Swiss-Prot Function]