Cdk5r1 (BC058697) Mouse Untagged Clone

CAT#: MC206164

Cdk5r1 (untagged) - Mouse cyclin-dependent kinase 5, regulatory subunit (p35) 1 (cDNA clone MGC:65701 IMAGE:6825809), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cdk5r1
• Synonyms: p35, Cdk5r, p25
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC058697
  GGAGCCGCCGCCGCGCCGAGTCGAGCACCCGGGCCGCGGCGCGCATTGCGGAGGGCCTGGGACGCAGCGG CTGCGCCTGCCGCGGGAGCCTGCCTGACTGCGGGTAAGCCTGCGCGGACCGGGGCCGTGTGCGCGGCCTG GTTGGATTCCTGCTGCGGAGGCCACTGCGGCTCTTTGACCGGTGCCGCAGTGGAAGCACAGGCTGGGGCT CGACGGGGCCGCAGCCCGGGGGTTCGGGCCTCGGAAGTGCGAGCGGAGGGGCGCGGCGTGGAGCCCCGCC CGGGGCTGAGAACCATCTTGTTTTCCACGCAGATCCGCAGGACTAAACGCGTCGTGTCCCGGGAGCGCCT CCTTTCTCTCTGCGGCCGCTACAGGCTCGGTAAGCCTTTACCCCCCTCCAGCCGGCAGGCTGGGCGCGCG GGGGTGCCGGCCCCTGCCGGGCGCGCAGTGGCACCATGGGCACGGTGCTGTCCCTATCCCCCAGCTATCG GAAGGCCACACTGTTTGAGGATGGCGCGGCCACCGTGGGCCACTACACGGCCGTGCAGAACAGCAAGAAC GCCAAGGACAAGAACCTGAAGCGGCACTCCATCATCTCGGTGCTGCCTTGGAAGAGGATCGTGGCGGTGT CAGCGAAGAAGAAGAACTCCAAGAAGGCGCAGCCCAACAGCAGCTACCAGAGCAACATCGCGCATCTCAA CAATGAGAACCTGAAGAAGTCGCTGTCCTGTGCCAACCTGTCCACATTCGCCCAGCCCCCGCCGGCTCAG CCGCCCGCACCCCCAGCCAGCCAGCTTTCTGGCTCCCAGACTGGGGTCTCCTCTTCTGTCAAGAAGGCCC CGCACCCTGCCATCACCTCTGCAGGGACACCCAAACGGGTCATCGTCCAGGCGTCCACTAGTGAGCTGCT GCGCTGCCTGGGTGAGTTTCTCTGCCGCCGGTGCTACCGCCTGAAGCACTTGTCCCCAACGGACCCCGTG CTCTGGCTGCGCAGCGTGGACCGCTCCCTGCTTCTGCAGGGCTGGCAGGACCAGGGTTTCATCACACCGG CCAATGTGGTCTTCCTCTACATGCTCTGCAGGGATGTCATCTCCTCTGAGGTGGGCTCCGACCATGAGCT CCAGGCTGTCCTGCTGACCTGTCTGTACCTCTCCTATTCCTACATGGGCAATGAGATCTCCTACCCGCTC AAGCCCTTCCTGGTAGAGAGCTGTAAGGAAGCCTTTTGGGACCGTTGCCTCTCAGTTATCAACCTCATGA GCTCCAAGATGCTGCAGATCAATGCCGACCCACACTATTTCACACAAGTGTTCTCTGACTTGAAGAATGA GAGCGGTCAGGAGGACAAGAAGCGACTCCTCCTGGGGCTGGATCGGTGAGCCCCTGTAGCCGGTATCCTG GCTCAAGGATTCCACTTGTTTTTAAATTTTATTACTAAAAGAATCAAGTTTTGTGTACAGTATGTGTCTA GCAGAGCCACCAAGGGCCTCTTCCCACGTTCTTTCCTTGGGGTTTTTTTTTAGCCCTTTCAAGAACTCTG GGGACTTTCGAACTGATGAACCTTGCGCGAACCCAAAAGATGCATTCAGAGCCACTTCGGCTGCTGACCA CTCACTTTCCGGGACTCAAGGGACTGACTTGCCCATGTCACCTGTACCCACGATGGATCCAGGGTAGATG AGGCTTCCCACTGTCCCATGATCGGAGCTGGGGCCCATGGCTGGTGGCCCTGGAGGAATCAGCCCTTTTC TGGGTATTGTTTCTCTTGAAGGCTCCTGGAGCTGGCTGTCCTGACTCAGGATCCAGGAGGTTGTGAGTGA GGCAAGATCTGCACAGCCCTGGGGCATCAGTGCAGGAGCCTGCAGAGACTGCTGATGACTGTTGACCATG CACGGCCCTGGTTTGCTGCGTGCTTTTTTAGGGAGAAGGGCTTTCCTTTCCTGGCAGGACAGAGCTCCCC TCCCATCCTTTTGTCTCTGCTCCCACGTTAGTGCTGGTTAATGAGGTGGTTTGCTCATTAGATTCCTCAC CCGTTTTGGGTCCCAGCTAAAGGATGAGGTGAAGCTAGGGGCAGCTCCTTCCCTGAGCGAGCTTTTCACA GTTTGTACCCTGTGTACAAAGCCAGAACAGCGCCGGGACCCACTAACAACATTGCCTTCTGGGCGGGTGG GTGTCTATGCCTGAGATCAGGTTGGTGCCCACTTGCATGCTAAGGCCTCTCGCTGGTGCCCGTGATCTTT GTTCTGTATCGTTGGGGGGAGGTGAGATCAGTCAATAGGGGTGTTGCTGTTTCCCATCCCTGCCCCCCCC CCAATTGTTAATTTTAAGCTGTTTCCAGGCAGCTCCGTCTCTTCCTGGAGAGGCTTTGCTCTGTGCAACC TACTGAGACAGATGCATTTGGGGACAATTACACGATGGAAGTGTGACCCCTGATCAGTTTGGAAGCTTGG TGACTGTGCAGCTGAGCACTTCCAGCTGCAGGGTGTGGCCGCCCACCTATCCCTGTCAGCTGCCTAACAC ACTCTGAACTTTAAGGGTTTTTCTTTCTAGTTTTCCCAGACTGGTGGCTTGGGGTTTGGAAGTGGTCCAA GAGAAGGGAGCTAGTCTTCTTGCATGGCCCTCACTCCAGCTTTGGGGAACAAAGAGCAATGTGAAGATAC TGCGGAGGGTTTCCTCTTCCTCTCCTGCTGCCCACCCCCGGGGGGGGGTGTGGGGGGCTGGGGCTGGGGC TGGGGGCTACAGTGAGGAAGGCGGAGGTCATCTTGCATAGGATTAGGTTCTAGGTGACTGCCAACTTCTT GCACAAGCACTACTGAAAAATTGCATATAAAGATAAAGCTGTGAAATTGAGGTCTCAATGGAAGAGGCCC GGAGCAGAGCCTTTCAGCCGACGACGTACTCACAGAGGTGGGGAAGCGGACCTGACAGACTAGAGAGCCT TTCCCCGGCCCCTCATCCGGGTTCCTAGAGAGCCGATCCTGGGCCCTCAGATGGTCTGACACGGAGCTGG AAAGCCCTGCAAGGCTTGCTGAGTGCAGGCCTCGCTGCAGCCCATCCTCACATCCTGCTGCCACGGTGAC CGCGCCTGGAGCCCCATGGGGCAGTAGGGAGAAGACCTTCAGGTGTCCAGTCTAAGCAGGAGCGGGCTCA TCCTCATAGCCTGCCAGCCGCTGTCGCTGGTCCACTGAGCTGCGGTAACAGGATTCCAGCTTTGCTGACT GTTTCCTTCTCTTTGTACTTAATTTTTAAAAAACAAAACAAAACATTTTTTTTGAGAAGGTGCATATTTC AGAAGTGGTCGGCAACTGAGGAAAGAGCTTCCTTGGTTCCATTGTGAAGCCCGTGTCCTCTCTGCTTGCG CTGGCTCTCAGTACTGTGTAAAGGAACGACCGCTAGACTTAAGTGTTCGAGCAAAGAACCTATCTGACAT GCTGCTATGAAGACACTTTTAGAACACACACACAAGATAGAAAAGAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: BC058697
• Insert Size: 924 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC058697, AAH58697
• RefSeq Size: 3542 bp
• RefSeq ORF: 924 bp
• Locus ID: 12569
• Cytogenetics: 11 47.94 cM
• Gene Summary: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.[UniProtKB/Swiss-Prot Function]