Ap3b1 (NM_009680) Mouse Untagged Clone

CAT#: MC203776

Ap3b1 (untagged) - Mouse adaptor-related protein complex 3, beta 1 subunit (Ap3b1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ap3b1
• Synonyms: AP-3; AU015684; beta3A; C78395; Hps2; pe; pearl; rim2
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC015068
  CCACGCGTCCGCCCACGCGTCCGCGGACGCGTGGGCCTCCGCCCCAGAACTAGTTTGGTTCGGTGTCCTC CGAACGCCAGCCATCCGTAGAGGACCCCGCACGCTCCCTCCCGCACCCGCCTGCTGGCCAGCACCGCCGC GATGTCTAGCAACAGTTTCGCCTACAACGAGCAGTCGGGAGGAGGGGAGGCGGCGGAGCTCGGGCAGGAG GCCACCTCGACCATCTCTCCCTCGGGCGCCTTCGGCCTCTTCAGCAGCGATTGGAAGAAGAATGAAGACC TGAAGCAGATGCTGGAGAGCAACAAAGATTCTGCCAAGCTAGATGCTATGAAGCGAATTGTTGGGATGAT TGCGAAGGGGAAAAATGCCTCGGAACTCTTCCCTGCTGTTGTGAAGAATGTGGCCAGTAAAAACATCGAG ATCAAGAAGTTGGTGTACGTTTACCTTGTCCGATATGCTGAAGAACAGCAGGACCTGGCTCTTCTGTCCA TAAGCACTTTCCAGCGAGCTTTGAAGGACCCGAATCAACTAATCCGTGCAAGTGCCTTGAGAGTTTTGTC AAGTATTAGAGTGCCAATTATCGTGCCTGTCATGATGCTGGCTATTAAGGAGGCTTCAGCTGACCTGTCG CCATATGTTAGGAAGAATGCAGCCCATGCTATTCAGAAGCTGTACAGTCTTGACCCTGAGCAGAAGGAGA TGTTAATTGAAGTCATTGAGAAGCTTCTGAAAGACAAGAGCACGCTGGTGGCTGGCAGTGTGGTGATGGC CTTTGAAGAAGTGTGCCCGGATAGAATCGATCTGATTCACAGGAATTACCGCAAGCTTTGTAACCTGCTG GTTGATGTTGAAGAGTGGGGGCAGGTGGTCATAATCCATATGCTAACAAGATACGCTCGGACCCAGTTTG TCAGTCCTTGGAGAGAGGATGGTGGTCTGGAAGACAATGAGAAGAACTTCTATGACTCTGAGGAGGAGGA GGAGAAGGAGAAGAGCAGCAGGAAGAAGTCGTATGCCATGGACCCAGACCACAGACTCTTAATTAGAAAC ACCAAGCCGTTGCTTCAGAGCAGGAATGCAGCGGTGGTTATGGCTGTCGCTCAGCTATATTGGCACATCT CACCCAAGTCGGAGGCTGGTGTCATTTCTAAATCACTGGTGCGCTTACTGCGCAGCAATAGGGAGGTGCA GTATATTGTATTGCAAAATATTGCAACTATGTCAATTGAGAGAAAGGGTATGTTTGAACCTTACCTGAAG AGTTTCTATGTCAGATCCACTGATCCAACTATGATCAAAACACTGAAGCTTGAAATTTTGACAAACTTGG CAAATGAAGCCAACATATCAACTCTTCTTCGAGAATTTCAGACCTACGTGAGAAGCCAGGACAAACAGTT TGCAGCAGCCACTATTCAGACCATAGGCAGATGTGCAACCAGCATTAGCGAGGTCACCGACACATGCCTC AACGGCCTGGTCTGCCTGCTGTCCAACAGGGATGAAATAGTTGTTGCTGAGAGTGTGGTTGTTATAAAGA AATTGTTGCAAATGCAGCCTGCACAGCATGGTGAAATTATCAGACATATGGCCAAGCTCTTGGACAGTAT CACTGTTCCTGTGGCTAGAGCAAGCATCCTTTGGCTAATTGGAGAAAACTGTGAACGAGTTCCTAAAATT GCTCCTGATGTTTTGAGGAAAATGGCTAAAAGTTTCACTAGTGAAGATGATCTCGTGAAACTGCAGATTT TAAATCTTGCAGCAAAATTGTATTTAACTAATTCCAAACAGACAAAATTGCTTACCCAGTACATATTAAA TCTCGGCAAGTATGATCAAAACTACGACATCAGAGACCGCACACGATTTATTAGGCAGCTTATTGTTCCG AACGAGAAGAGTGGAGCCTTAAGTAAATATGCCAAAAAAATCTTCCTAGCACCGAAGCCTGCGCCACTGC TCGAGTCTCCCTTTAAAGATAGGGATCGCTTCCAGCTTGGCACCTTATCTCATACTCTCAACATTAAAGC GTCCGGGTACCTGGAATTATCTAATTGGCCAGAGGTGGCGCCTGACCCATCGGTTCGCAATGTAGAAGTA ATAGAGTCAGCAAAAGAATGGACCCCACTTGGGAAAACAAAGAAAGAAAAACCCATGAAGAAATTTTACT CTGAATCTGAGGAGGAGGAGGACGAGGACGAGGACGAGGACGAGGAGGAGGAGGAGGAAGAAAAGGAAGA TGAGGATGAGAACCCCTCTGATAGCAGCAGTGACAGTGAGAGCGAGTCCGGAAGTGAGAGTGGAGACACA GGCACCAGCAATGAGGACAGCAGTGAGGACTCGTCCAGTGGACAAGACAACGAGACCGGAAGCCAGGCAG AAGCGGAACGCCAGAAGGTGGCCAAGAGGAACTCCAAAACCAAGAGGAAAAGTGATTCAGAAAATAGGGA GAAGAAAAATGAAAACTCAAAAGCTTCTGAATCGTCCAGTGAGGAGTCCAGTTCCATGGAAGACAGTTCT TCCGAGTCAGAGTCAGAGTCAGGCTCTGACAGTGAGCCTGCGCCCAGAAACGTGGCTCCGGCAAAAGAAA GAAAACCCCAGCAAGAAAGACATCCTCCCTCCAAAGATGTTTTCCTTCTAGATCTGGACGACTTTAACCC AGTATCCACCCCAGTTGCCCTTCCTACACCAGCCCTTTCTCCAAGCTTGATAGCTGATCTTGAAGGTCTA AACTTGTCAACTTCTTCATCAGTCATCAACGTCAGTACGCCTGTCTTCGTGCCAACAAAAACACATGAGC TGCTTCACCGAATGCATGGGAAAGGACTGGCCGCCCACTACTGCTTCCCAAGACAGCCCTGCATCTTCAG TGACAAGATGGTCTCTGTACAGATCACCCTGACTAATACTTCTGATCGAAAAATAGAAAACATCCACATA GGGGGGAAAGGGCTTCCTGTGGGCATGCAGATGCATGCCTTTCATCCAATAGACTCTCTGGAGCCTAAGG GGTCCGTGACTGTCTCAGTGGGTATTGACTTCTGTGATTCTACACAGACGGCCAGTTTCCAATTGTGCAC CAAGGATGACTGCTTCAACGTCACCCTCCAGCCACCTGTTGGGGAGCTGCTTTCACCTGTGGCCATGTCA GAGAAGGACTTTAAGAAGGAGCAAGGAACGCTCACTGGAATGAACGAGACTTCGGCTACACTCATCGCTG CTCCGCAGAACTTCACTCCCTCCATGATCCTCCAGAAGGTTGTAAATGTGGCCAACCTCGGTGCTGTGCC TTCCAGCCAAGATAACGTACACAGGTTTGCAGCTAGAACTGTGCACAGTGGGTCACTGATGCTAGTCACA GTGGAACTGAAGGAAGGCTCCACAGCCCAGCTTATCATCAACACCGAGAAAACCGTGATTGGTTCTGTTC TGCTGCGGGAGCTGAAGCCTGTCCTGTCCCAGGGGTAACCTGCTTACATCTGGACTTCAGAATCTGGCAC ACAACAAAAGTGCCTGGCACCCACTGCTGCTGCCTTTCATTTATAATAATAGCCCTTCCATCTGGCAGCA GGAAGAGCGCACTCTCGACATTCTTGTCTCTGCTTTAGAATGCTGCTGTGTCTGTCATGTGTGCACTCCT CGCCCCTCCTCGCTTTGCTAACCAAAGAACATATATTTTACTGTCCATTTCCTCAGCTCCCCAGTCCGAG TGGCATTTTCTCTGCCCTCCGACTTCTTTTGACCTCATCTTCCTTCTGGGTTTTGAGAACAGTGGGTGTG AATCAGTGCTTGGCAATCGTCCTTCTTACAGCAGTAAGCAAAAATTAGCAAGGAACGTGTCTGCATGGCC TCTCAGCTTGGTATGTGAAAAGGAAATAGCATACTTTTTCAAAAATAAATAAATAAAAATGGCATCTCTG AAAATCCCATTCCTTGATTTTCCTGGTATTGTAATTGGTTATTGACAATTGTCATCATGAAATTACCCCT GAATAATCAGGTAAATAAAGGAGTATATGAATAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_009680
• Insert Size: 3327 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC015068, AAH15068
• RefSeq Size: 4038 bp
• RefSeq ORF: 3327 bp
• Locus ID: 11774
• UniProt ID: Q9Z1T1
• Cytogenetics: 13 49.22 cM
• Gene Summary: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.[UniProtKB/Swiss-Prot Function]