Tulp3 (NM_011657) Mouse Untagged Clone

CAT#: MC202681

Tulp3 (untagged) - Mouse tubby-like protein 3 (Tulp3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Tulp3
• Synonyms: 2310022L06Rik; AI316887
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC060068 sequence for NM_011657
  GGTATGGAGGCGGCGCGCTGCGCACCCGGACCCCGCGGGGACAGTGCCTTTGACGATGAGACCCTGAGGC TTCGGCAGCTGAAGCTGGACAATCAGAGGGCACTGCTGGAGAAGAAGCAGAGAAAGAAGCGCCTTGAGCC ACTCATGGTACAGCCAAACCCAGAAGCCAGGCTGCGAAGGTTAAAGCCACGAGGCAGTGAGGAGCACACG CCTCTGGTGGACCCTCAGATGCCTCGCAGCGACGTCATCCTACACGGCATCGACGGTCCAGCTGCTTTCC TTAAGCCAGAGGCTCAGGATTTGGAAAGCAAGCCTCAGGTTCTCTCTGTGGGCTCCCCTGCCCCAGAAGA AGGCACGGAAGGGAGTGCAGATGGGGAAAGCCCCGAGGAGACAGCCCCCAAGCCAGACCTTCAGGAGATT CTCCAAAAACACGGCATCTTGAGTAGTGTGAACTATGACGAGGAGCCTGACAAGGAGGAAGATGAGGGGG GAAACCTCAGCTCCCCGTCGGCTCGCTCAGAGGAGAGTGCTGCAGCCAGCCAGAAAGCAGCCTCGGAGAC AGGAGCTTCCGGTGTGACAGCCCAGCAGGGTGACGCCCAGCTTGGAGAAGTGGAGAATTTAGAGGACTTT GCGTATAGCCCTGCCCCTCGGGGTGTCACGGTGAAGTGTAAAGTAACCAGGGATAAGAAAGGCATGGACC GTGGCCTCTTCCCCACCTACTATATGCACCTGGAACGGGAGGAGAACCGCAAGATATTTCTTCTAGCCGG TAGAAAGCGGAAAAAGAGCAAAACGTCCAACTACCTGGTCTCCACAGACCCGACAGATTTGTCTCGTGAA GGGGAAAGTTACATTGGCAAACTCAGATCCAATCTCATGGGGACCAAGTTCACAGTGTATGACCATGGTG TCAACCCAGTCAAGGCCCAGGGTCTGGTGGAGAAGGCCCACACCCGCCAGGAGCTGGCTGCTATCTGTTA TGAAACAAATGTCCTCGGTTTCAAAGGTCCCAGGAAAATGTCTGTGATCATCCCGGGGATGAACATGAAC CATGAGCGCATCCCTTTCAGGCCACGAAATGAACACGAGAGCTTGCTTTCAAAATGGCAAAACAAATCCA TGGAGAACCTGATCGAGCTGCACAACAAGGCCCCGGTGTGGAATGACGACACCCAGTCCTACGTGCTGAA CTTTCACGGCAGAGTCACCCAGGCATCCGTGAAAAACTTCCAGATCGTCCACGGGAATGACCCTGACTAC ATCGTCATGCAGTTTGGACGCGTGGCTGATGACGTGTTCACACTGGACTATAACTACCCACTGTGCGCAC TTCAAGCCTTCGCCATCGGGCTGTCCAGCTTTGACAGCAAGCTGGCGTGTGAATGAGAAGCAGCAAGCAG GGGATTTCTTCACCACAGAGCCTTCAAGAGCAGAAAGCTGCTGCCTCTGCCCCTGCCCCTGCCCCTGCCC CTGCCCCTGCCCCTGCCCCTGCCCCTGCCCCTGCCCCTGCCCCTGCCCCTGCCCCTGCCCTAGCACAAGA AGAGCAACATTCTGCCCCTCTGGTGAATGATCCAGTGTGTGTGTGTGTGTGAATGTGCATGTGTGTGTTT GTTTATACATGCATACACATTCACACATGGATGCATGCTTCCACGTACTCGTTCATGCCTTCTCTGAACT TCAGAGACCTGGTCATAGATTACAACTTCTCATGTGTGAGAGATGGCTTAAAGCACAGGGAAGTAGACAC CCAGGCACACTGGTGTCTCCTGATCGCACAACAGACTCTGTGTGGTGAGTGTAGCTTTCATGTGCTCGGG CACTTCCAACAGAATCAGGTTCTAATGATTTAATACTTGGGCCTCCTGTTTTGAAGGCCCTTTCAAAAGG GGGCTTTTCCCTTGGATGCCTTTAGCCCAGGAGCCTGCAGCCTTCCTCAGCCAATGGTCTGATAGTGTCT CTTGCACTGACCCCAGTCAGGTCCTTTAGCACAAAACAGCCATAACTAGTTGGTGCACAAAGAGTGTAGC TGTGTCCCAATAAAACTTTATTTACAAAGTGGGCATTGGCCTAGTTTGGCCTGTGACTCTGGTTCGCAGG CCTGCCTTGGCTGTGTCCCTGTCCTCCAAGGCTGGAGCATCTTCCAGGCTAGATGTGGAGAGGCGGGGGG TGGTTTACTTTTCAGTAGCAGCAGACTGACATTTTATTTTTATTTTTACTTTATTTTTTTTTCCCATGGA TCTCTGTGTAGCCCTGGCTATCCTGGAACTTATTCTGTAGACCAGGCTGGCCTCAGAGATCCACCTGCCT CTGCCCCCCAAGTGCTGGAATTAAAGGCTTACACTACTGTGCCTGGCCATAGACAGACTCTTAAGAGGAA TTCTTGCCGAATCTACTCTTGGTAGCTTTTGCCTCATGGAGATTATGGCTGCAGAGTGTCATATATCATC TTGGGACATGTGACACTAGTTTGTTCGTGGGTCTGAAAGGCTCTGCTGTCCCCAGCCTGCCTCTTGCTTA TTCTCAGAGTAGGTTGGTGGGCAGCCATCTCAGAAGCATGACTGTGGCCAGATCTTCGGAATCTTTGCTC TCTGGAATCTTAATCTAGTGTCTCCTTAGAGGCAGCAAGAGTCTTGGTGAGGAGGTCACCTCGCCGACAC TCCACAGGCTTTGCCTGTCAGCTTTGTCCTCCAGCCTCGAAACCTGGCCCACACCAGTGGAGACACTGCC CTGCATGCTGAGTCTTTGAGATCTTGAACATCTCGAACATCTCCCAGCGAATCATGACAAATTCCTCAAG GTCCCCAGCCTACAGTGTACCTGAACTTAAGAATTCAAAAACTTTGGGTCTACATTCAGTGGTCCCCCAC TCTCAAACTGGCAACTGCTCCGTGGTTTTTCCTGTATGGAGGAGGTCCCTGCATCCCTGCATCCTGTTGC TCCATGCTCACAGCTGTGTGACGACTACAGCGTGAGATCTGGGAGGTGAGACCTGTGCTAAGGCCAGTGT CTTGCCTGTCCCTTCAGATGTCACTGTCTCTGCCTCTGGCAGGCGTCCCATCAAGTGCCTTGTTCATAAA TGTGCTCTGAAACCTGACACACCTCTGCTTTCCCAGACGAGCCACCTTTGTTGAGTGAAAACTGCTCTCT GTCTCCACTTGAAGGGGGTGGGGCTATGACTTTCTGCCCAGCCTAGAGAGCTGTATACTCCCATTTCATG GACTCTGCTTGAGTGTGCAGGTTTTACATGAATTCTATTTATACCTTTTGTATGCCACATAAATAAAGAT AATTTATATAAAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAT
• Restriction Sites: AscI-NotI
• ACCN: NM_011657
• Insert Size: 1383 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC060068, AAH60068
• RefSeq Size: 3332 bp
• RefSeq ORF: 1383 bp
• Locus ID: 22158
• UniProt ID: O88413
• Cytogenetics: 6 62.96 cM
• Gene Summary: Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.[UniProtKB/Swiss-Prot Function]