Atxn1 (NM_009124) Mouse Untagged Clone

CAT#: MC202345

Atxn1 (untagged) - Mouse ataxin 1 (Atxn1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Atxn1
• Synonyms: 2900016G23Rik; Atx1; C85907; ENSMUSG00000074917; Gm10786; Sca1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC058178 sequence for NM_009124
  GCCGTACAGGACCTGTTTCACTGCAGGGGGATCCAAAACAAGCCCTGTGGAGCCGCAGCTAGAGCTACAG CAGCCGCAGGACACTGTGTCTCTCCCTCTGTTACCCCTTCCCCACGCAACCCCAGATCCATTTACACTTT ACAAAGTATCCTGCACCGTGCAACAAGTACGAGGGCGGTCGCTTCAAGCTGCAGATCTGTCTGTCATCCT TATCCAACAGTCTCTTCCTCCACTCCCTCCACAGGGAAGGGCGTCACCTGTCAGATTGCAGCATCCTGGA ACAGAATGAAAGGATCTGTGTTGAAACAGCTACAGTAGGGTTACAGTAGACCCTGAGAAAAACAGAGTGG ACTTCAGCCTGCACGGATGAGCTTGAAGCAGGAATGGTTTGGGGTTCAGGCCTCTTACACTGAATTTCTC TACTGCCACCCTTTCTACTCAAGCAACATCTTCAGGAAAAGATCTCCCGGGAAGGAAGTGGCTGCTTGTG GCTTTGCACTGTGATGAAGGCAAATGGTACAGTTTTCCAAAGAAAATAGACCAAAACTTTCTTCTTGAGA AGAAACAAACCTGCTGTTGGCAGAGGAATCCGGAGCTGCCACTGCCAGCCTAAAGAACCCACGGGGAGAT GATTCCCCATGAAGGGCCTGGATCCCCTACAGAAATCCAATGTGACTCTCTGTTTATCAGACTAAAACCA GAGCCGGCCAGCCAGTGAAACAGCCACCGTGGAGGGGGGACGGCGAAAAATGAAATCCAACCAAGAGCGG AGCAACGAATGCCTGCCTCCCAAGAAACGTGAGATCCCCGCCACCAGCCGGCCCTCGGAGGAGAAGGCCA CTGCTCTGCCCAGCGACAACCACTGCGTGGAGGGTGTGGCCTGGCTCCCCAGCACCCCTGGCATCCGCGG CCATGGGGGTGGGCGGCACGGGTCAGCAGGGACTTCCGGGGAGCATGGTTTACAAGGAATGGGTTTACAT AAAGCACTGTCCGCAGGGCTGGATTACTCCCCACCCAGTGCCCCCAGGTCAGTCCCCACAGCCAACACGC TGCCCACCGTGTACCCTCCTCCTCAGTCAGGGACCCCGGTGTCTCCTGTGCAGTACGCCCACCTTTCGCA TACCTTCCAGTTCATTGGGTCCTCCCAATACAGTGGGCCTTACGCGGGCTTTATCCCTTCCCAGCTGATC TCCCCATCAGGCAACCCGGTCACCAGTGCAGTAGCCTCAGCTGCAGGGGCCACCACTCCATCACAGCGCT CCCAGCTGGAGGCTTATTCCACCCTGCTGGCCAACATGGGCAGTCTGAGCCAGGCACCAGGACATAAGGT TGAGCCCCCTCCGCAGCAGCACCTCAGCAGGGCTGCAGGATTAGTCAACCCGGGGTCCCCTCCTCCACCC ACCCAGCAGAACCAGTACATCCATATTTCCAGCTCTCCACAGAGCTCCGGGCGGGCGACATCTCCCCCAC CCATCCCGGTCCACCTCCATCCCCATCAGACGATGATCCCGCACACACTCACCCTGGGGCCTTCATCCCA GGTGGTTGTGCAATATAGTGATGCCGGAGGCCACTTTGTTCCTCGAGAGTCCACCAAAAAAGCCGAGAGC AGCAGGTTGCAGCAGGCTATGCAAGCCAAGGAAGTCCTGAATGGGGAGATGGAGAAAAGCCGGAGGTATG GGGCATCATCTTCTGTGGAGCTGAGCCTAGGCAAGGCAAGCAGTAAGTCAGTGCCTCATCCCTATGAGTC CAGGCATGTGGTGGTCCACCCAAGCCCAGCAGACTACAGCAGTCGTGATACCTCCGGGGTCCGTGGATCT GTGATGGTTCTGCCTAATAGCAGCACACCCTCAGCCGACCTGGAGGCCCAGCAGACCACGCATCGAGAGG CCTCCCCATCCACCCTCAATGACAAGAGCGGCCTGCACCTAGGGAAGCCGGGCCACAGGTCTTATGCGCT GTCCCCCCACACGGTCATTCAGACCACACACAGTGCATCAGAGCCTCTCCCGGTGGGCCTACCAGCCACG GCCTTCTACGCTGGCACTCAACCTCCTGTCATCGGCTACCTGAGCGGCCAGCAGCAAGCAATCACCTATG CTGGTGGTCTGCCGCAGCACCTGGTGATCCCAGGTAACCAGCCCCTGCTCATCCCGGTGGGCAGCCCTGA CATGGACACGCCTGGGGCAGCCTCGGCCATCGTGACGTCATCACCCCAGTTTGCTGCAGTACCTCACACG TTTGTCACCACCGCCCTGCCCAAGAGCGAGAACTTCAACCCAGAGGCTCTGGTCACCCAGGCTGCCTACC CAGCCATGGTGCAGGCCCAGATCCACCTGCCGGTGGTGCAGTCCGTGGCGTCCCCCACCACGGCGTCTCC CACGCTGCCGCCATATTTCATGAAAGGCTCCATCATCCAGCTGGCCAACGGGGAGCTGAAGAAGGTGGAG GACCTGAAGACGGAGGATTTCATCCAGAGTGCAGAGATTAGCAATGACCTCAAGATCGACTCCAGTACTG TGGAGAGAATCGAGGAGAGCCACAGCCCCGGGGTGGCCGTGATACAGTTTGCTGTTGGTGAACACCGAGC CCAGGTCAGTGTCGAAGTCTTGGTAGAGTATCCTTTTTTTGTATTTGGACAGGGCTGGTCATCCTGCTGT CCTGAGCGGACCAGCCAGCTCTTTGATCTGCCGTGTTCCAAACTCTCTGTTGGGGACGTCTGCATCTCGC TCACCCTCAAGAACCTGAAGAATGGCTCTGTTAAAAAGGGCCAGCCTGTGGACCCTGCCAGCGTCCTGCT GAAGCAGGCAAAGACCGACAGCCTGGCTGGCAGCAGACACAGATACGCGGAGCAGGAAAACGGAATCAAC CAGGGAAGCGCCCAGGTGCTCTCTGAGAATGGCGAACTGAAGTTTCCAGAAAAAATAGGATTGCCTGCAG CACCCTTCCTCAGCAAAATAGAACCGAGCAAACCCACAGCCACGAGGAAGAGGAGGTGGTCGGCGCCGGA GACCCGTAAACTGGAGAAGTCGGAGGACGAGCCACCTTTGACTCTTCCCAAGCCTTCGCTCATTCCTCAG GAGGTTAAGATCTGCATCGAAGGCCGATCTAACGTGGGCAAGTAGAGACCTTGCGGGCAGCGGAGGCCCG GGGCCTCCTTTTACTGTCTGTATCCAGATTACTGTACTGTAGGCTAAGTAACACAGTATTTACATGTTAC ATCCTCTTTAGGTTTGTATTCTAACCTTGTCATTAGAGTCAAACAGGTGTGTCGCAGGAGACTGGTGCGT TTGCATTGTCTGCAAGGGTCTGTTGAGGAGCTGGTGGGTGGAGGATGGTCAGAACCATGTCCATGGAGCT CCCGGGCATCCTTAGTGGCCCTGAATGTGGCTTCATCAGCCCCTGCCTTCTCCGGCAGTGTGCAGAGTCG AGGGGCATCAGTTCCCACTGGTTTCAAGAACAAACACAGTGGGAAGTATCCTGCAAGGGAGTGTCTGGGT GCGTGTCCCTTGTGAAGGAGTGCGAGTGAGGGTGTCTCTTTCTCTGCCTCTGTCTCCCTCACTTGCTCCC TCTCAGTGTGGGGTTGGGGGACCTGGGTTTCCCACCTGCAAAGTCATCAGGGAACCCAGCTTCCAGGCAT TGTAGGGAGACATCAGACAGGCAGATGGGAAACTAGTTTCAAAGAACGTGGTTCTCTCCAACATATTTTA CAATAAAAAGCAACTTTTAATCAACAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_009124
• Insert Size: 2376 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC058178, AAH58178
• RefSeq Size: 3750 bp
• RefSeq ORF: 2376 bp
• Locus ID: 20238
• UniProt ID: P54254
• Cytogenetics: 13 21.98 cM
• Gene Summary: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (By similarity). May be involved in RNA metabolism (By similarity). In concert with CIC and ATXN1L, involved in brain development (PubMed:28288114).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode the same isoform (b). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.