Rin1 (NM_145495) Mouse Untagged Clone

CAT#: MC200740

Rin1 (untagged) - Mouse Ras and Rab interactor 1 (Rin1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Rin1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC011277 sequence for NM_145495
  GGGTTGGATTGTCTTCCTGAGTCCCAGGAGAAGCCGAAGGAGCTCCCAGCCATGGAAGACCCTGGTGAGA CCGGAGCACACCCTCTGGGAGCCACCAACCTGAACTTTGTACCTGGGCACCAACAGAAAGAAAAGCCATC TACAGACCCACTGTATGACACACCTGATACCAGAGGGGTACAGGCAGGCGGGTCCCAACAGCCAGCACGT ACTGTGAGCCTTCGGGAGCGGCTGCTGATCACCCGGCCTGTGTGGTTACAGCTGCGGGCCAACGCTGCAG CCGCGCTGCACGTGCTGAGGACAGAGCCTCCGGGGACCTTCCTGGTGCGGAAATCTAACACTCGCCAGTG CCAGGCTCTGTGTGTGCGGCTGCCAGAAGCTAGTGGCCCCTCTTTTGTCTCCAGCCACTATATCGAAGAG AGTACTGGCGGTGTCTCTTTGGAGGGCTCAGAGCTCATGTTCCAGGACCTGGTGCAGCTCATCTGTGGAT ACTGCCGTACCAGAGCCATTCATCAGGCAGCCACCCACAAAGAGCTGGAGGCCATCTCCCATCTGGGCAT GGAGTTCTGGAGCTCCTCACTCAACACCAAGGACCAACAGAGGCCTTCGGAAGCCCCACCCATACCCCGG CTGAAGGCTCGCTCCCCTCAAGAGCTGGATCAGGGCACTGGTGCTGCCCTCTGCTTCTTCAACCCCCTCT TCCCCGGGGATCTGGGCCCCACCAAACGAGAGAAATTCAAGAGGAGTTTCAAAGTGCGAGTGTCCACCGA GACCTCCAGCCCTCTGTCTCCACCTGCTGTGCCGCCTCCCCCAGTCCCGGTGCTGCCAGGGACATCTTCC AGCCAAACGGAAAGACTGCCCCCTCGACAGCTGCTGCAGAGGGAGAGCTCAGTGGGATATCGTGTGCCAG GAAGTGCTGCCAGCCCATGTCTTCCTCCCCTACCTTCCCTTCAGGAGGTGGACTGCTGCTCTCCCAGCAG CTCAGAGGAGGAGGGCTCTTCAGGAAGCCCTACAACCTCCCCACGCCTAAGCCGCCCAAGGCACCGGCGG CCTCTGCTTCGGTCCATGAGTTCTGCTTTCTGCTCTCTGCTGGCACCAGAGAGGCAGGTGGGCCGGGCAG CCACAATGCTAATGCAAAACCGATACACAGCCGTGGGTCAGCTAGTGCAGGACCTACTGACCCAGGTTCG GGCTGGTCCCGAGCCCCGGGAGTTGCAGGGCATCCGCCAGGCCCTAAGTCGGGCCCGGGCCATGCTGAGC GCAGAGCTGGGCCCTGAGAAGCTGCTACCACCAGAGCGGCTGGAATTGGTCCTGGAGAAGTCCCTGCATC GCTCTGTTCTCAAACCTCTTCGACCCATTCTGGCTGCCCGCCTGCGGCGCCGGCTTTCCGCAGATGGTTC CCTCGGCCGCCTAGCTGAGGGCTTCCGCCTGGCCCGGACCCAGGGGCCTGGAGCCTTCGGGTCCCACCTG ACTCTTTCTTCCCCAGTGGAGACAGAACAGGTGCGCCAGAAGCTGCTGCAGCTCCTTCGTGCCTACTCAC CTAGTGCCCAGGTCAAGTGGCTCCTGCAGGCCTGCAAGCTGCTATACACAGCCCTGAAGAGCCAGGCAGG AGAGAATGCAGGTGCTGATGAGTTCCTGCCTCTGCTGAGCCTTGTTTTGGCCCAGTGCGACCTTCCTGAC CTCCTGTTAGAAGCTGAGTATATGTCAGAGCTCCTGGAACCCACCCTGCTCACTGGAGAGGGTGGCTACT ACCTGACCAGCCTCTCAGCCAGCCTGGCCTTGTTGAGTGGCCTAAGCCAGGCCCGAGCACTGCCACTCAG CCCAGCACAGGAGCTCCAGCGCTCCCTGGCCCTCTGGGAACAGCGCCGCCTGCCGGCCACCCACAGCTTC CAGCATCTCCTCCGAGTAGCCTACCAGGACCCCAGCACAGGTTGCACCTCCAAGACCCTGGCTGTGCCCC CAGGGTCTTCAATTGCCACGTTGAGCCAACTCTGTGCTACCAAGTTCCGAGTGACCCAACCAGATGCGTT TGGCCTCTTCCTCTACAAGGACCAGGGCTACCATCGCCTGCCCCCTGAAGCCCTAGCCCACAGGCTTCCT GCAACTGGCTACCTCATCTATCGCCGGGCAGAGCGCCCTGAGACCCAGGGGGCTGTAGCGGAAAAGGCAA AGACAGGCAGCAAGGGGCCAGAGGCAGGAGCATGGGAGGAGGAGACAGGGGGTCTAAACAGAGAAGGGAA ACCTCGGATAGCTGTTGACCAAGAAGGCAAGGATCAGGCCAGAGGAGGTCACATAGGACCAGAGGAACAA AAGGCAGAAGGAAGCCAGGCTTTGGAAGAGTAGCTAGGAAGAACCAAAGGGGTTACCTGGGCCCCCGGGA GCCTCTAAGTCCACTCTTCCCAGCTGCCAAGCTTCCTTTACCACCCACCCACAGTTCTCTGTGGTGTCTG CCACCACCTCTGGCCGATCTTCATAAGTCCACCTGCTAGGGAACAGGGAGCTGGCCATATAGACTAGAGC AGCGTTAAGAGAGCTGGGAGACTCACAGACCCTCTGTTTAAGGCCCCTGGCTTCTGTCTCCCCATAGCCC ACAGGGATAAACGTGTCTGGTAAGGGGAAAATCCTCCTGATAGCCATAGGGGCGTGGTGGGAGGGTAGTC CTGGCTTCTTTTGCCTCTCCCACTGCCCATGGAGAGATGCTGGAGCATCAAGACCCTGTGCAACTCCAGT CTCTCCTAGTTCTAGGGGTCAGGGAACCAGAATGGCAGCAAAGCTCCCCAAACTAACAGCTCTTCTCAGA CATAGCATCTGGTGTGCAAAGAAGGGATATGACTGCTGTTCTGCAGGGTTCCTAGAGTGACCCAGGACCT ACATGGATGGTTGGCGGCTCAGCTCAGGCAGGAGAAAGAAGAAAGAATGAGTGTTAGCAGCTATGGCAAG CCTGTCCCGTAGGCAGCCTCTACCAGGCTACTACCCTCACCTGTGTCTTCTTTCCCGGTCAGTTCAGAGA TGGTTGTCACCCTGGAGGTCAGGCTGTAGGAGAGAAAGCATCTATGTTCCAGTCTTTTCTCACGATCAGA AATCTGTTGAGGGGCTGGTGAGATGGCTCAGTGGTAAGAGCACCCAACTGCTCTTCCGAAGGTCCAGAGT TCAAATCCCAGCAACCACATGGTGGCTCACAACCATCTGTAACGAGATCTGACTCCCTCTTGTGGTGTGT CAGAAGACAGCTACAGAAATCTGTTGAGACACTGAAGTATTTCTGGGAAATTGGACCCTGAGAAATAATG CACGCTAGCAGGAAGAGAAGTTTCCAGAACAGAGAGGTGCTCCACAAACATTGCCGTCGTACCCCACTCC TTGGGTCCTTACTAAAGCTTGATAATGAGGAATGGTGTAGCTGTGGGCCCCACGGCAGTACAGGTTAGGT AATTCCCAAGACGTTCCAGCAGACTAGCCCTCCAGGCTCAGGCAGCAGCCCCAGAGGGAAGCCCACTGCA AATCTGAGCAGAGAAAAATACCCACCAAAAGCCACAAGAGGGCGCATACAGCCCGAGAAGCTGCTGAGGG TCACCCACCCTCTTCACTCCCCTACCCTGCCCGAGCAGTGGGAGGGGGGTGGCTAAAGAGAATTTAAGAG CCTCAGAATGTGGACAGTCACTGGCCTCACACACTCTTATAGCAGCTTGGGACATGCAGAGCAGAGACCC CTTATAGTCAGAGATTCTTAGAAGAGGATTGTTTCCGGACAAAGGAGGACCACAGCCAGGCTCAGAGCTG CTCTCCTGGGCCTCTGAGTACCAGGGCACCAACTTAGATGTGATGCACATACCAACAGGAGGTAGACTTT CAAATCCACATCTAGTCAGTATAGGGTTCCAAACTAGTCACTAGGCCACCAGTGTTCCTTGCCCACTTCT ATGCCCCTCCCTCCGCAGGAGGGAAAAGTGTGTGATAAGGGACAAGTTCATCTGATATCTAACATCTGGT GGGGAGGGTGGCCACGGTTCTTTTGGCCTTTTCTCCACCACCCAGGAGGGGCCACACACAAGGCTGCTGG ATCTTCAAGGCTCTAAACAGCATGGCCCCCTATTCCATTATATGTCTTTCCTTCCTCCCTAATCCTTTGT ACAGGATGGAGCACTCTGCAGGTGCTCAATAAATGGTGTCTACTGAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_145495
• Insert Size: 2292 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC011277, AAH11277
• RefSeq Size: 4216 bp
• RefSeq ORF: 2292 bp
• Locus ID: 225870
• UniProt ID: Q921Q7
• Cytogenetics: 19 A
• Gene Summary: Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis (By similarity).[UniProtKB/Swiss-Prot Function]