Cx3cl1 (NM_009142) Mouse Untagged Clone

CAT#: MC200619

Cx3cl1 (untagged) - Mouse chemokine (C-X3-C motif) ligand 1 (Cx3cl1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cx3cl1
• Synonyms: AB030188; ABCD-3; AI848747; CX3C; Cxc3; D8Bwg0439e; Scyd1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC006650 sequence for NM_009142
  GCCCAGCCTCCTGGCCCGCCGAATTCCTGCACTCCAGCCATGGCTCCCTCGCCGCTCGCGTGGCTGCTGC GCCTGGCCGCGTTCTTCCATTTGTGTACTCTGCTGCCGGGTCAGCACCTCGGCATGACGAAATGCGAAAT CATGTGCGACAAGATGACCTCACGAATCCCAGTGGCTTTGCTCATCCGCTATCAGCTAAACCAGGAGTCC TGCGGCAAGCGTGCCATTGTCCTGGAGACGACACAGCACAGACGCTTCTGTGCTGACCCGAAGGAGAAAT GGGTCCAAGACGCCATGAAGCATCTGGATCACCAGGCTGCTGCCCTCACTAAAAATGGTGGCAAGTTTGA GAAGCGGGTGGACAATGTGACACCTGGGATCACCTTGGCCACTAGGGGACTGTCCCCATCTGCCCTGACA AAGCCTGAATCCGCCACATTGGAAGACCTTGCTTTGGAACTGACTACTATTTCCCAGGAGGCCAGGGGGA CCATGGGGACTTCCCAAGAGCCACCGGCAGCAGTGACCGGATCATCTCTCTCAACTTCCGAGGCACAGGA TGCAGGGCTTACGGCTAAGCCTCAGAGCATTGGAAGTTTTGAGGCGGCTGACATCTCCACCACCGTTTGG CCGAGTCCTGCTGTCTACCAATCTGGATCTAGCTCCTGGGCTGAGGAAAAAGCTACTGAGTCCCCCTCCA CTACAGCCCCATCTCCTCAGGTGTCCACTACTTCACCTTCAACCCCAGAGGAAAATGTTGGGTCCGAAGG CCAACCCCCATGGGTCCAGGGACAGGACCTCAGTCCAGAGAAGTCTCTAGGGTCTGAGGAGATAAACCCA GTTCATACTGATAATTTCCAGGAGAGGGGGCCTGGCAACACAGTCCACCCCTCAGTGGCTCCCATCTCCT CTGAAGAGACCCCCAGCCCAGAGCTGGTGGCCTCGGGCAGCCAGGCTCCTAAGATAGAGGAACCCATCCA TGCCACTGCAGATCCCCAGAAACTGAGTGTGCTTATCACTCCTGTCCCCGACACCCAGGCAGCCACAAGG AGGCAGGCAGTGGGGCTACTGGCTTTCCTTGGTCTTCTTTTCTGCCTAGGGGTGGCCATGTTTGCTTACC AGAGCCTTCAGGGCTGTCCCCGCAAAATGGCGGGGGAAATGGTAGAAGGCCTCCGCTACGTCCCCCGTAG CTGTGGCAGTAACTCATACGTCCTGGTGCCAGTGTGAGCTGCTTGCCTGCCTGCCTGTGTCCAGAGTGTG ATTCGGACAGCTGTCTGGGGACCCCCCCCCATCCTCATACCCACCTTCATCCACGCTGGGGAAATGGGAA TGGAGAAGCTGGACCCTCCAGGGGCTGTGGGCTCCATCCAATCCCCCCTCCCCCGAGGGGTGGCCCCGGA GGCCACCCTAGACCACTATTCACTTATCAGAGACAGAGCAGGTGACCTTCCAGCTCCTCTATATTTGAAA GAATCCTCTGCTGCTGGCTGGTTAGAGGGGCCCTTGACACCCCAACTCCAGTGAACAATTATTTATTGGA TTCCCAGCCCCTGCGACGACACCTGTTTCCCGCGCGCACCGTGGTCCGCCCATATCACAAGCAGCAGGCC AGGCCTATCTGCCTGTCCCCCTGACCTCCTTGTGTCTCCTGGCTTTGCTGCAGTCGCCAGCCCTTCTCCT CCCCGGCCAGCTGCGGTGCTATCTGCCCTATGTCTCCCTCTATCCCCTGTACAGAGCGCACCACCATCAC CATCAACACCGCTGTTGTGTCTTTTCTTGCATGAGGTTAAAGCTGTGTTTTCTGGAGCTCTCCGGGAAGG GAGACAAGCTTGCGAGAGGGTTTAAAGTGTTCCTCCCCAGACTTGGATGTGCTGTGAAGGCATGCTGCGT CTGAAGGAAGGGTCCAGTCCCCACTCGGCTACCAGCACCACAAAGTGCCCCACCTGTAAAAGGAAAGAAA CGTGGTCCAGAGCTGGCAATAACCTATGGCCCTGACATCATCACTTTCTCTGAGATCCTTGTCTCCACCC CTGGGTGCAACCCCACCCCTTATCAACATTAATAGTCACTGCCATTCCACTGGACTGACATTTTTGTACC CTGTGATTCTGAGGGCTGGCAAGGAGTGGCTTGAGAGTGCAGATCGTACCCTGTATGCCCCCCCCCCAAA TGGAGGCTGAGTTGGGGACTTGCAGGAACAGAGGCCAACTCAGATGGCTTCCCCTGTGTTCTCACTAGAA ACCCCTCCCCCATGCACCAAGGTGACAGTCACAGGTCTGCCCTGGCTAAAGGACAAGCCACATAGGAAAG ATTAGGACAAGCCCCTCGGAGGCAGAGGATCCAGGGTAAACCCCTGGAGTGGCCACAAACCCAATTTCAG TGTAGGGACTTGTGCATGTGTGTACTTGCATAGTCAGACAGAGGCTGCCAGGGTCCTTTCCTGTCTCTGA GAGCAGTGTTCACGCCAAGGACTCACCTTTGCCCCCATTGCAGGCAGGGCCAGAACTCCCATAGCATTCT CCAAGAGCCCTGTGACATTTTCTGGAAGGGACTCTGCCCTGGGCGCAAAGTGACTGCTGAAGCAAGGAGC AGCTGAGCAGCACCCCAGCGGAGCTGAGCCGGCAGGCCACGCCCCTCGGGGGGGGGCATTTCTACCCACC CTGCTCTGAATAGCTCCAACTTCACCTTAGGAGCCTCCCAGGGGCGAGCTTCACCCAGAAGCCAGTGACT CACTCCTTGATTGGTGGAAGCTCAGTTGGCTCCTGAGAGTGAGGAAGCCAACCCTTTGTCGACCCTCCTC CTGGGAAGCCTGTGGGCGGCTCTGATCATGCTCCACAGAACCAGTTGTAGGCCTGAGCCGCAGCAGCCCG AGTGCACTATATCCTGGCTCCTTCGGTGGGGAACCTTTAAGGGTTGGGACACCCGTCATCGGACTTTGTT GGTTCCTCCCTCCCAGAGCAGAATGTGGGCCGTAACAATCTGAGGAGGACTTTGAAAGTTGTTGATCCTT TAGGGTTTTTTTTCAAGCATCATTACCAATGTCTGTGCCATTTTGTATTTTACTAATAAAATTTTAAAGT CTTGTGAATTAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_009142
• Insert Size: 1188 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC006650, AAH06650
• RefSeq Size: 3106 bp
• RefSeq ORF: 1188 bp
• Locus ID: 20312
• UniProt ID: O35188
• Cytogenetics: 8 46.79 cM
• Gene Summary: Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 and to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1 (By similarity). The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium (PubMed:9177350, PubMed:10382755).[UniProtKB/Swiss-Prot Function]