Fcgrt (BC003786) Mouse Untagged Clone

CAT#: MC200332

Fcgrt (untagged) - Mouse Fc receptor, IgG, alpha chain transporter (cDNA clone MGC:6014 IMAGE:3485649), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fcgrt
• Synonyms: FcRn
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC003786
  CTGGAGGCTCTAAGCAGAGGATCCATCGGCTGCAGGCAGAGGGAAGAGGGCCTCTGTGAGGAACAGGCTG AGCGTCAGAGGAGGAGGCCCAGGCCTGGTTCTCTAGCTCTGTAATTAATTAACTAAAGTGGATCAAATGA GAAGGTGAAAGTTCACAGAGGAACACTCCTGTCTGTCGTCTTGGACTGGGTCTCCATCCCACCATCCAGC GTCCTGGTCTACGAAGAGTCCACAGGGACCTTGTGAAGAATCAACAAGGCGGGGTCCAGAGGAGTCACGT GTCCCTTCCACTCCGGGTCACCCTGTCGGAATGGGGATGCCACTGCCCTGGGCCCTCAGCCTCTTGTTGG TCCTCCTGCCTCAGACCTGGGGCTCAGAGACCCGCCCCCCACTGATGTATCATCTCACGGCTGTGTCAAA CCCATCTACGGGGCTTCCCTCTTTCTGGGCCACAGGCTGGTTGGGTCCTCAGCAGTATCTGACCTACAAC AGCCTGCGGCAGGAAGCTGACCCCTGTGGGGCCTGGATGTGGGAAAATCAGGTGTCTTGGTATTGGGAGA AGGAGACCACAGACCTCAAAAGCAAAGAACAGCTCTTCTTGGAGGCCCTCAAGACCCTGGAGAAGATATT AAATGGTCAGAAGAGGGGGACCTACACACTGCAGGGCCTGCTGGGCTGTGAACTGGCCTCGGATAATTCC TCAGTGCCCACGGCTGTGTTTGCCCTCAATGGTGAGGAGTTTATGAAATTCAACCCAAGAATCGGCAATT GGACTGGGGAGTGGCCTGAGACGGAAATCGTTGCTAATCTGTGGATGAAGCAGCCTGATGCGGCCAGGAA GGAGAGCGAGTTCCTGCTAAACTCTTGTCCGGAGCGACTGCTAGGCCACCTGGAGAGGGGCCGACGGAAC CTGGAGTGGAAGGAGCCGCCGTCTATGCGCCTGAAGGCCCGTCCTGGCAACTCTGGCTCCTCCGTGCTGA CCTGTGCTGCTTTCTCCTTCTACCCACCGGAGCTCAAGTTCCGATTCCTGCGCAATGGGCTAGCCTCAGG CTCCGGGAATTGCAGCACTGGTCCCAATGGAGATGGCTCTTTCCACGCATGGTCATTGCTGGAGGTCAAA CGTGGAGATGAGCACCATTATCAATGTCAAGTGGAGCATGAGGGGCTGGCACAGCCTCTCACTGTGGACC TAGATTCATCAGCCAGATCTTCTGTGCCTGTGGTTGGAATCGTTCTTGGTTTATTGCTGGTGGTAGTGGC CATCGCAGGCGGTGTGCTGCTGTGGGGCAGGATGCGCAGCGGTCTGCCAGCCCCATGGCTTTCTCTCAGC GGCGATGACTCTGGTGACCTGTTGCCTGGTGGGAACTTGCCCCCAGAAGCTGAACCTCAAGGTGCAAATG CCTTTCCAGCCACTTCCTGATGCAGACTCGGGCCCCCTGCCCACTGCAGCCTTTCGGGCTGTGTGACCTC CTGAACTGTCTCCGAGCCTCCTGAGGGAGCCTGGGCCCGATGTCCTCCCATGGATCCCTGCTTTTGTGGC CTGCTTCAGTTTCCCTTCTTAATGTACATGGTTGTTTTCCATCTCCACATAAATTTGGCCCCAAAAAAAA AAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: BC003786
• Insert Size: 1110 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC003786, AAH03786
• RefSeq Size: 1617 bp
• RefSeq ORF: 1110 bp
• Locus ID: 14132
• Cytogenetics: 7 29.12 cM
• Gene Summary: Binds to the Fc region of monomeric immunoglobulins gamma (PubMed:7504013). Mediates the selective uptake of IgG from milk and helps newborn animals to acquire passive immunity. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids (By similarity). Possible role in transfer of immunoglobulin G from mother to fetus (By similarity).[UniProtKB/Swiss-Prot Function]