p53 (TP53) Mouse Monoclonal Antibody [Clone ID: UMAB206]

CAT#: UM870098

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P53 (TP53) mouse monoclonal antibody, clone UMAB206


 Product Datasheet for 'UM870098'

  View other "UMAB206" antibodies (2)

USD 180.00


Availability*
In Stock

Size
    • 30 ul


Specifications

Product Data
Clone Name UMAB206
Applications 10k-ChIP, IF, IHC, WB
Recommend Dilution IHC 1:100~200
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human TP53 (NP_000537) produced in SF9 cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 44.1 kDa
Gene Name Homo sapiens tumor protein p53 (TP53), transcript variant 1
Background This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
Synonyms BCC7; LFS1; P53; TRP53
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Protein Pathways Amyotrophic lateral sclerosis (ALS), Apoptosis, Basal cell carcinoma, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, Glioma, Huntington's disease, MAPK signaling pathway, Melanoma, Neurotrophin signaling pathway, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer, Thyroid cancer, Wnt signaling pathway

Other Versions

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Transient overexpression lysate of tumor protein p53 (TP53), transcript variant 1
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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