CD3E Mouse Monoclonal Antibody [Clone ID: UMAB54]
CD3E mouse monoclonal antibody,clone UMAB54
Product Datasheet for 'UM500048'
|Applications||IF, IHC, WB|
|Recommend Dilution||IHC 1:100, IF 1:100|
|Immunogen||Full length human recombinant protein of human CD3E(NP_000724) produced in HEK293T cell.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Concentration||0.5~1.0 mg/ml (Lot Dependent)|
|Purification||Purified from cell culture supernatant by affinity chromatography|
|Predicted Protein Size||20.7 kDa|
|Gene Name||Homo sapiens CD3e molecule (CD3E)|
|Background||The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]|
|Synonyms||IMD18; T3E; TCRE|
|Protein Families||Druggable Genome, Transmembrane|
|Protein Pathways||Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.