CD3E Mouse Monoclonal Antibody [Clone ID: UMAB54]
USD 436.00
USD 867.00
Specifications
Product Data | |
Clone Name | UMAB54 |
Applications | IF, IHC, WB |
Recommended Dilution | IHC 1:100, IF 1:100 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CD3E(NP_000724) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 20.7 kDa |
Gene Name | CD3e molecule |
Database Link | |
Background | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008] |
Synonyms | IMD18; T3E; TCRE |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
UM500048 | CD3E mouse monoclonal antibody,clone UMAB54 |
USD 564.00 |
|
UM500048CF | Carrier-free (BSA/glycerol-free) CD3E mouse monoclonal antibody,clone UMAB54 |
USD 657.00 |
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