BRCC36 (BRCC3) Mouse Monoclonal Antibody [Clone ID: OTI6G7]
CAT#: TA811409S
BRCC3 mouse monoclonal antibody,clone OTI6G7
Size: 100 ul
View other "OTI6G7" antibodies (4)
Special Offer: Get this product for $99/€99. Use code: "Truesample".
USD 200.00
USD 436.00
Specifications
Product Data | |
Clone Name | OTI6G7 |
Applications | WB |
Recommended Dilution | WB 1:500 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 41-316 of human BRCC3 (NP_077308) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | BRCA1/BRCA2-containing complex subunit 3 |
Database Link | |
Background | This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jun 2011] |
Synonyms | BRCC36; C6.1A; CXorf53 |
Reference Data | |
Protein Families | Druggable Genome, Protease |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF811409 | Carrier-free (BSA/glycerol-free) BRCC3 mouse monoclonal antibody,clone OTI6G7 |
USD 600.00 |
|
TA811409 | BRCC3 mouse monoclonal antibody,clone OTI6G7 |
USD 447.00 |
|
TA811409AM | BRCC3 mouse monoclonal antibody,clone OTI6G7, Biotinylated |
USD 509.00 |
|
TA811409BM | BRCC3 mouse monoclonal antibody,clone OTI6G7, HRP conjugated |
USD 509.00 |
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