Kv beta 1 (KCNAB1) Mouse Monoclonal Antibody [Clone ID: OTI2F1]
KCNAB1 (Kv beta 1) mouse monoclonal antibody, clone OTI2F1 (formerly 2F1)
Product Datasheet for 'TA503970'
|Applications||FC, IF, WB|
|Recommend Dilution||WB 1:1000, IF 1:100, FLOW 1:100|
|Immunogen||Full length human recombinant protein of KCNAB1(NP_751891) produced in HEK293T cell.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purification||Purified from mouse ascites fluids by affinity chromatography|
|Predicted Protein Size||44.5 kDa|
|Gene Name||potassium voltage-gated channel subfamily A member regulatory beta subunit 1|
|Background||Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Jul 2008]|
|Synonyms||AKR6A3; hKvb3; hKvBeta3; KCNA1B; KV-BETA-1; Kvb1.3|
|Protein Families||Druggable Genome, Ion Channels: Other|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.