Kv beta 1 (KCNAB1) Mouse Monoclonal Antibody [Clone ID: OTI2F1]

CAT#: TA503970S

KCNAB1 (Kv beta 1) mouse monoclonal antibody, clone OTI2F1 (formerly 2F1)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KCNAB1 (RC207384, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KCNAB1. Positive lysates LY403531 (100ug) and LC403531 (20ug) can be purchased separately from OriGene.

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  Western blot analysis of extracts (10ug) from 4 different cell lines by using anti-KCNAB1 monoclonal antibody (1:200).

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  Anti-KCNAB1 mouse monoclonal antibody (TA503970) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY KCNAB1 (RC207384).

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  Flow cytometric Analysis of Jurkat cells, using anti-KCNAB1 antibody (TA503970), (Red), compared to a nonspecific negative control antibody, (Blue).

Specifications

Product Data

• Clone Name: OTI2F1
• Applications: FC, IF, WB
• Recommended Dilution: WB 1:1000, IF 1:100, FLOW 1:100
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of KCNAB1(NP_751891) produced in HEK293T cell.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.96 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 44.5 kDa
• Gene Name: potassium voltage-gated channel subfamily A regulatory beta subunit 1
• Database Link:
  NP_751891
  Entrez Gene 16497 MouseEntrez Gene 29737 RatEntrez Gene 7881 Human
  UniProt ID Q14722
• Background: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Jul 2008]
• Synonyms: AKR6A3; hKvb3; hKvBeta3; KCNA1B; KV-BETA-1; Kvb1.3

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other