TrkC (NTRK3) Mouse Monoclonal Antibody [Clone ID: OTI4E10]

CAT#: TA500538

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Anti-NTRK3 (TrkC) mouse monoclonal antibody, clone OTI4E10 (formerly 4E10)



  View other "OTI4E10" antibodies (4)

Special Offer: Try sample size of this antibody at $99/€99. Use code "TrueSample".

USD 447.00


Availability*
In Stock

Size
    • 100 ul


Other products for "NTRK3"

Specifications

Product Data
Clone Name OTI4E10
Applications IF, IHC, WB
Recommended Dilution WB 1:1000 IHC 1:50 IF 1:100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human NTRK3 expression vector
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.9 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 94.4 kDa
Gene Name neurotrophic receptor tyrosine kinase 3
Background This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Synonyms GP145-TrkC; TRKC; gp145(trkC)
Reference Data
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Neurotrophin signaling pathway

Other Versions

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Recombinant protein of human neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 3
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