ATP7B Rabbit Polyclonal Antibody

CAT#: TA356396

ATP7B Antibody - middle region

Product Images

Host: Rabbit Target Name: ATP7B Sample Type: Lung Tumor lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATP7B
• Specificity: Expected reactivity: Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
  Homology: Dog: 82%; Guinea Pig: 82%; Horse: 82%; Human: 100%; Mouse: 91%; Rabbit: 92%; Rat: 91%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 74kDa
• Gene Name: ATPase copper transporting beta
• Database Link:
  NP_000044.2
  Entrez Gene 540 Human
  UniProt ID P35670
• Background: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
• Synonyms: PWD; WC1; WD; WND

Reference Data

• Protein Families: Druggable Genome, Transmembrane