CACNB1 Rabbit Polyclonal Antibody

CAT#: TA349730

Rabbit Polyclonal Anti-CACNB1 Antibody

Product Images

Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Mouse spleen tissue, Primary antibody: (CACNB1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes

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  The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using (CACNB1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1000-2000, WB: 200-1000, IHC: 50-200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human CACNB1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 66 kDa
• Gene Name: calcium voltage-gated channel auxiliary subunit beta 1
• Database Link:
  NP_954855
  Entrez Gene 12295 MouseEntrez Gene 50688 RatEntrez Gene 782 Human
  UniProt ID Q02641
• Background: The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
• Synonyms: CAB1; CACNLB1; CCHLB1

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway