ROR1 Goat Polyclonal Antibody
USD 665.00
USD 200.00
USD 867.00
Specifications
Product Data | |
Applications | IHC, PEP-ELISA |
Recommended Dilution | IHC: 3-6 ug/ml |
Reactivities | Human (Expected from sequence similarity: Mouse, Rat) |
Host | Goat |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for Anti-ROR1 Antibody: Peptide with sequence C-GNKSQKPYKIDSKQA, from the C-Terminus (near) of the protein sequence according to NP_005003.2. |
Formulation | Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Concentration | lot specific |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | receptor tyrosine kinase-like orphan receptor 1 |
Database Link | |
Background | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012] |
Synonyms | dJ537F10.1; NTRKR1 |
Note | This antibody is expected to recognize isoform 1 (NP_005003.2) only. |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Documents
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