hnRNP K (HNRNPK) Mouse Monoclonal Antibody [Clone ID: F45P9C7]

CAT#: TA327942

Mouse Monoclonal anti-hnRNPK Antibody

Product Images

HeLa cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with anti-hnRNPK antibody (clone F45P9C7). Proteins were visualized using a goat anti-mouse-IgG secondary conjugated to HRP and chemiluminescence detection.

Specifications

Product Data

• Clone Name: F45P9C7
• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human, Mouse, Rat, Rabbit, Chicken
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Ovalbumin-conjugated synthetic Peptide SVKQYSGKFF
• Formulation:

  This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.

• Concentration: lot specific
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51 kD
• Gene Name: heterogeneous nuclear ribonucleoprotein K
• Database Link:
  NP_002131
  Entrez Gene 15387 MouseEntrez Gene 117282 RatEntrez Gene 3190 Human
  UniProt ID P61978
• Background: hnRNP K (Heterogeneous nuclear ribonucleoprotein K) is a pre-mRNA binding protein and a component of hnRNP complexes providing substrate for pre-mRNA processing before becoming translatable mRNAs in cytoplasm. This protein containing KH domains and is ubiquitously expressed in the cytoplasm and the nucleus with a predicted molecular weight approximately 51 kD. hnRNP K expression and function are increased by epidermal growth factor (EGF). hnRNP K acts as transcriptional regulator and functions in nucleocytoplasmic shuttling, and is modified by phosphorylation (PKC δ, c-Src) and acetylation. Clone F45P9C7 has been shown to be useful for western blotting and immunohistochemistry of human, mouse, rat, rabbit and chicken hnRNP K.
• Synonyms: CSBP; HNRPK; TUNP

Reference Data

• Protein Pathways: Spliceosome