ALDH1A1 Rabbit Polyclonal Antibody

CAT#: TA327181

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Rabbit anti-ALDH1A1 Polyclonal Antibody


Product Datasheet for 'TA327181'


USD 345.00


Availability*
3 Weeks

Size
    • 100 ul


Product images

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB 1:500 - 1:2000, IHC 1:50- 1:200, IF 1:50- 1:200
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant protein of human ALDH1A1
Formulation Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration 1 mg/ml
Purification Affinity purification
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name aldehyde dehydrogenase 1 family member A1
Background The aldehyde dehydrogenase family is a large group of enzymes that oxidize aldehydes formed through metabolic processes to their carboxylic acids. ALDH1A1 is a liver cytosolic isoform of acetaldehyde dehydrogenase and is involved in the major pathway of alcohol metabolism along with alcohol dehydrogenase. ALDH1A1 is also known as retinal dehydrogenase 1 and is involved in retinol metabolism, converting retinol to retinoic acid. Recent studies suggest that control of retinoid signaling through ALDH1A1 may influence hematopoietic stem cell differentiation. There has been recent interest in ALDH1 isoforms as predictive biomarkers in disease. Several studies have suggested that ALDH1A1 is a potential marker for cancer stem cells and chemoresistance in several tumor types, such as melanoma, lung cancer, glioblastoma.
Synonyms ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS
Protein Pathways Metabolic pathways, Retinol metabolism
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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