TrkB (NTRK2) Rabbit Polyclonal Antibody

CAT#: TA311826

Rabbit polyclonal Trk B (Tyr515) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from NIH/3T3 cells using Trk B (phospho-Tyr515) antibody.The lane on the right is treated with the synthesized peptide.

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  Western blot analysis of extracts from K562 cells (Lane 2) and 3T3 cells (Lane 3), using Trk (Phospho-Tyr515) Antibody. The lane on the left is treated with synthesized peptide.

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  Immunohistochemical analysis of paraffin-embedded human brain tissue using Trk B (phospho-Tyr515) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~3000, IHC: 1:50~1:100, ELISA: 1:5000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Trk B around the phosphorylation site of tyrosine 515 (P-Q-YP-F-G).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: neurotrophic receptor tyrosine kinase 2
• Database Link:
  NP_006171
  Entrez Gene 18212 MouseEntrez Gene 25054 RatEntrez Gene 4915 Human
  UniProt ID Q16620
• Synonyms: GP145-TrkB; trk-B; TRKB
• Note: Trk B (phospho-Tyr515) antibody detects endogenous levels of Trk B only when phosphorylated at tyrosine 515. The amino acid position may vary depending on the source of reference sequence: position 516 base on NP_001018074.1, position 532 base on NP_006171.2.

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: MAPK signaling pathway, Neurotrophin signaling pathway