FRA1 (FOSL1) Goat Polyclonal Antibody

CAT#: TA302492

Goat Polyclonal Antibody against FRA1 / FOSL1

Product Images

TA302492 (1ug/ml) staining of Human Bone Marrow lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1,000. WB: 0.1-0.3µg/ml.
• Reactivities: Human (Expected from sequence similarity: Mouse, Rat, Dog, Pig, Cow)
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-QREIEELQKQKER, from the internal region of the protein sequence according to NP_005429.1.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 33037 Da
• Gene Name: FOS like 1, AP-1 transcription factor subunit
• Database Link:
  NP_005429
  Entrez Gene 14283 MouseEntrez Gene 25445 RatEntrez Gene 483724 DogEntrez Gene 8061 Human
  UniProt ID P15407
• Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
• Synonyms: FRA; fra-1; FRA1

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Wnt signaling pathway