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GFAP (Glial Fibrillary Acidic Protein) is a type III intermediate filament protein expressed by numerous cell types in the central nervous system (CNS), including astrocytes and ependymal cells, during development. GFAP is important in Alexander's disease's pathogenesis and repair after CNS injury. Read the blog to learn more »

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ST2: A potential biomarker for cardiovascular disease

The ST2 gene is a potential biomarker of poor prognosis in cardiovascular diseases. ST2 is present in two critical isoforms: Membrane-bound ST2 (ST2L) and soluble ST2 (sST2). ST2L binds with IL33 and has cardioprotective effects like decreased cardiac damage, prevention of apoptosis, lowered inflammatory effect. However, binding of sST2 to IL33 causes the protective effect to disappear Learn more »

IL6: A Pleiotropic Inflammatory Cytokine

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