IRE1 (ERN2) (NM_033266) Human Recombinant Protein

CAT#: TP762684

Purified recombinant protein of Human endoplasmic reticulum to nucleus signaling 2 (ERN2)

Product Images

Purified recombinant protein ERN2 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of ERN2
• Tag: N-GST and C-HIS
• Predicted MW: 135.2 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_150296
• Locus ID: 10595
• UniProt ID: Q76MJ5, A5YM46, A5YM65
• Cytogenetics: 16p12.2
• Refseq Size: 3549
• Refseq ORF: 2922
• Synonyms: hIRE2p; IRE1-BETA; IRE1b; IRE2p
• Summary: Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.[UniProtKB/Swiss-Prot Function]
• Protein Families: Druggable Genome, Protein Kinase