C14orf172 (TRMT61A) (NM_152307) Human Recombinant Protein

CAT#: TP761479

Purified recombinant protein of Human tRNA methyltransferase 61 homolog A (S. cerevisiae) (TRMT61A), full length, with N-terminal HIS tag, expressed in E.coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length TRMT61A
• Tag: N-His
• Predicted MW: 31.2 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_689520
• Locus ID: 115708
• UniProt ID: Q96FX7, A0A024R6Q2
• Cytogenetics: 14q32.33
• Refseq Size: 3257
• Refseq ORF: 867
• Synonyms: C14orf172; GCD14; Gcd14p; hTRM61; TRM61
• Summary: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA (PubMed:16043508). Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries (PubMed:29107537, PubMed:29072297).[UniProtKB/Swiss-Prot Function]
• Protein Families: Druggable Genome