Glutathione Transferase zeta 1 (GSTZ1) (NM_145871) Human Recombinant Protein
Purified recombinant protein of Human glutathione transferase zeta 1 (GSTZ1), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.coli, 50ug
Specifications
Product Data | |
Description | Purified recombinant protein of Human glutathione transferase zeta 1 (GSTZ1), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.coli, 50ug |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence | A DNA sequence encoding human full-length GSTZ1 |
Tag | N-His |
Predicted MW | 19.2 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_665878 |
Locus ID | 2954 |
Refseq Size | 1145 |
Cytogenetics | 14q24.3 |
Refseq ORF | 522 |
Synonyms | GSTZ1-1; MAAI; MAAID; MAI |
Summary | This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme catalyzes the conversion of maleylacetoacetate to fumarylacetoacatate, which is one of the steps in the phenylalanine/tyrosine degradation pathway. Deficiency of a similar gene in mouse causes oxidative stress. Several transcript variants of this gene encode multiple protein isoforms. [provided by RefSeq, Jul 2015] |
Protein Families | Druggable Genome |
Protein Pathways | Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Tyrosine metabolism |
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