HIV Recombinant Protein

CAT#: TP727570

Recombinant HIV gp120 (C-8His)

Specifications

Product Data

• Species: HIV
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Glu498
• Tag: C-8His
• Buffer: Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
• Note: Recombinant HIV 1 Envelope glycoprotein gp120 is produced by our Mammalian expression system and the target gene encoding Met1-Glu498 is expressed with a 8His tag at the C-terminus.
• Stability: 12 months from date of despatch

Reference Data

• Summary: Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequence inhibit immune function in vitro and in vivo.