Pcsk9 Mouse Recombinant Protein

CAT#: TP727008

Recombinant Mouse Proprotein Convertase Subtilisin/Kexin Type 9/PCSK9 (C-6His)

Specifications

Product Data

• Species: Mouse
• Protein Source: Human
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Gln35-Gln692
• Tag: C-His
• Buffer: Supplied as a 0.2 um filtered solution of 50mM HEPES, 150mM NaCl, 20% Glycerol, pH 7.4.
• Note: Recombinant Mouse Proprotein Convertase Subtilisin/Kexin Type 9 is produced by our Mammalian expression system and the target gene encoding Gln35-Gln155&Ser156-Gln694 is expressed with a 6His tag at the C-terminus.
• Stability: 12 months from date of despatch

Reference Data

• Locus ID: 100102
• UniProt ID: Q80W65
• Summary: Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis.PCSK9 also plays a role in neural development.